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نتائج ل
"Metastases"
صنف حسب:
Publisher Correction: Bach's symphony for metastasis
بواسطة
Dart, Anna
في
Metastases
2019
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Journal Article
Author Correction: A hypoxia-responsive TRAF6-ATM-H2AX signalling axis promotes HIF1alpha activation, tumorigenesis and metastasis
2020
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Journal Article
Enhanced axillary assessment using intradermally injected microbubbles and contrast-enhanced ultrasound identifies axillary disease missed by conventional B-mode ultrasound that may be clinically relevant
2020
Purpose The purpose of this study is to measure pre-treatment diagnostic yield of malignant lymph nodes (LN) using contrast-enhanced ultrasound (CEUS) in addition to B-mode axillary ultrasound and compare clinicopathological features, response to NACT and long-term outcomes of patients with malignant LN detected with B-mode ultrasound versus CEUS. Methods Between August 2009 and October 2016, NACT patients were identified from a prospective database. Follow-up data were collected until May 2019. Results 288 consecutive NACT patients were identified; 77 were excluded, 110 had malignant LN identified by B-mode ultrasound (Group A) and 101 patients with negative B-mode axillary ultrasound had CEUS with biopsy of sentinel lymph nodes (SLN). In two cases CEUS failed. Malignant SLN were identified in 35/99 (35%) of B-mode ultrasound-negative cases (Group B). Patients in Group A were similar to those in Group B in age, mean diagnostic tumour size, grade and oestrogen receptor status. More Group A patients had a ductal phenotype. In the breast, 34 (31%) Group A patients and 8 (23%) Group B patients achieved a pathological complete response (PCR). In the axilla, 41 (37%) and 13 (37%) Groups A and B patients, respectively, had LN PCR. The systemic relapse rate was not statistically different (5% and 16% for Groups A and B, respectively). Conclusions Enhanced assessment with CEUS before NACT identifies patients with axillary metastases missed by conventional B-mode ultrasound. Without CEUS, 22 (63%) of cases in Group B (negative B-mode ultrasound) may have been erroneously classed as progressive disease by surgical SLN excision after NACT.
Journal Article
Rare axillary cancer of unknown primary originating from the breast of a 64-year-old male patient: A case report and literature review
2024
Cancers of unknown primary (CUPs) are a heterogeneous group of tumors characterized by a difficult diagnosis. The primitive tumor remains unknown, whereas metastases are the most common manifestation. Occult male breast cancers are very rare types of CUPs. The present study describes the case of a 64-year-old man affected by a CUP of presumed mammary origin. The aim of the article and the present review was to focus on their management. To the best of our knowledge, only thirteen cases have been reported in the literature. Because no specific guidelines are available, various approaches have been applied, influencing the treatment and the prognosis of patients with CUP. Key words: male breast cancer, occult male breast cancer, male breast cancer of unknown primary
Journal Article