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Axial flow pumps often experience uneven distribution of axial force on the blades when deviating from design conditions, which can easily lead to local damage to the pump blades. In response to this issue, this article conducts a detailed study on the hydraulic and axial force characteristics of large vertical axial flow pumping stations in China based on constant and non-constant numerical simulation research methods. Research has found that under biased operating conditions, due to the angle between the water flow direction inside the impeller and the impeller blades, the water body collides with the blades, resulting in concentrated pressure distribution on both sides of the inlet side of the impeller blades. Under low flow conditions, the high axial force area of the impeller blade is concentrated in the middle and rear position of the suction surface, while under high flow conditions, the high axial force area is widely distributed. Under the conditions of 0.8 Q to 1.4 Q , the fluctuation of axial force on the impeller blades is mainly affected by the rotation of the impeller blades. However, under low flow conditions, due to the turbulence of the flow state, there is no obvious pattern of axial force variation on the impeller blades. In addition, under different flow conditions, there is no obvious pattern in the fluctuation of axial force on the guide vanes. This also proves that there are problems such as uneven axial force distribution and no periodic changes in the impeller blades under low flow conditions, which can easily lead to damage to the impeller blades. The above analysis can provide some reference for the design of impeller blades.

For traction substation (TS), the harmonic current spectrum distribution of the left and right power supply sections has a large difference under different EMU operating conditions. This phenomenon will further affect the harmonic distribution of the entire traction power supply system and has the risk of harmonic distortion. At the same time, it may also cause interference to the communication line. In this paper, the transient direct current control technology is used to realize the converter of EMU, and then the TS side harmonic model under regenerative braking condition is realized. The harmonic problem, control process, and negative sequence problem caused by locomotive traction braking on the TS side under various working conditions are analyzed in detail. After connecting the C-type filter to the traction network side of the system, the THD (total harmonic distortion) is within the standard range, while the negative sequence problem of the system has worsened. Therefore, the parameters of the filter were optimized to improve both harmonics and negative sequence problems by combining the negative sequence characteristics under various operating conditions. The results show that the improved treatment can effectively control the harmonic problem.

Arctic and alpine tundra ecosystems are large reservoirs of organic carbon 1 , 2 . Climate warming may stimulate ecosystem respiration and release carbon into the atmosphere 3 , 4 . The magnitude and persistency of this stimulation and the environmental mechanisms that drive its variation remain uncertain 5 – 7 . This hampers the accuracy of global land carbon–climate feedback projections 7 , 8 . Here we synthesize 136 datasets from 56 open-top chamber in situ warming experiments located at 28 arctic and alpine tundra sites which have been running for less than 1 year up to 25 years. We show that a mean rise of 1.4 °C [confidence interval (CI) 0.9–2.0 °C] in air and 0.4 °C [CI 0.2–0.7 °C] in soil temperature results in an increase in growing season ecosystem respiration by 30% [CI 22–38%] ( n  = 136). Our findings indicate that the stimulation of ecosystem respiration was due to increases in both plant-related and microbial respiration ( n  = 9) and continued for at least 25 years ( n  = 136). The magnitude of the warming effects on respiration was driven by variation in warming-induced changes in local soil conditions, that is, changes in total nitrogen concentration and pH and by context-dependent spatial variation in these conditions, in particular total nitrogen concentration and the carbon:nitrogen ratio. Tundra sites with stronger nitrogen limitations and sites in which warming had stimulated plant and microbial nutrient turnover seemed particularly sensitive in their respiration response to warming. The results highlight the importance of local soil conditions and warming-induced changes therein for future climatic impacts on respiration. Datasets from in situ warming experiments across 28 arctic and alpine tundra sites covering  a span of less than 1 year up to 25 years show the importance of local soil conditions and warming-induced changes therein for future climatic impacts on ecosystem respiration.

Mitigating loss of genetic diversity is a major global biodiversity challenge 1 , 2 , 3 – 4 . To meet recent international commitments to maintain genetic diversity within species 5 , 6 , we need to understand relationships between threats, conservation management and genetic diversity change. Here we conduct a global analysis of genetic diversity change via meta-analysis of all available temporal measures of genetic diversity from more than three decades of research. We show that within-population genetic diversity is being lost over timescales likely to have been impacted by human activities, and that some conservation actions may mitigate this loss. Our dataset includes 628 species (animals, plants, fungi and chromists) across all terrestrial and most marine realms on Earth. Threats impacted two-thirds of the populations that we analysed, and less than half of the populations analysed received conservation management. Genetic diversity loss occurs globally and is a realistic prediction for many species, especially birds and mammals, in the face of threats such as land use change, disease, abiotic natural phenomena and harvesting or harassment. Conservation strategies designed to improve environmental conditions, increase population growth rates and introduce new individuals (for example, restoring connectivity or performing translocations) may maintain or even increase genetic diversity. Our findings underscore the urgent need for active, genetically informed conservation interventions to halt genetic diversity loss. A comprehensive meta-analysis of global terrestrial and marine genetic diversity covering more than three decades of research demonstrates rapid loss of genetic diversity and identifies conservation interventions that could mitigate this process.

Flue-cured tobacco ( Nicotiana tabacum L.) is a major cash crop in Yunnan, China, and the yield, chemical components, and their proportions decide the quality of tobacco leaves. To understand the effects of environmental factors (soil and climatic factors) on the yield and quality of flue-cured tobacco and determine the main regulating factors, we selected three flue-cured tobacco cultivars [K326, Yunyan87 (Yun87), and Honghuadajinyuan (Hongda)] grown in the Honghe Tobacco Zone. Indices related to yield and economic traits, chemical component properties, soil physical and chemical properties, and climatic factors at different planting sites, were evaluated. We used variance analysis, correlation analysis, and redundancy analysis (RDA) in this study. The results showed that the yield and chemical component properties of flue-cured tobacco, except for the number of left leaves and plant total sugar (PTS) content, were significantly correlated with climatic factors. Particularly, the yield increased in drier and sunnier weather. In terms of the carbon supply capacity, PTS, petroleum ether (PPE), and starch contents (PS) were higher under high-altitude and high-latitude climatic conditions, whereas for the nitrogen supply capacity, plant nitrogen (PTN) and nicotine (PN) contents improved under low-altitude and low-latitude climatic conditions. PTS, reducing sugar (PRS), potassium (PTK), chlorine (PCL), and PPE contents were negatively related to soil clay content, soil pH, and soil organic matter, whereas PRS and PTK contents were positively correlated with alkali-hydrolyzed nitrogen (AN). According to RDA, the soil clay, AN, available phosphorus (AP), and soil chlorine content (SCL) strongly affected the quality of flue-cured tobacco. The quality of the K326 and Yun87 cultivars was mostly influenced by moisture, whereas the quality of the Hongda cultivar was mostly affected by temperature. In conclusion, compared with soil properties, climatic factors more significantly affect the yield and quality of Honghe flue-cured tobacco leaves.

For over half a century, worldwide growth in affluence has continuously increased resource use and pollutant emissions far more rapidly than these have been reduced through better technology. The affluent citizens of the world are responsible for most environmental impacts and are central to any future prospect of retreating to safer environmental conditions. We summarise the evidence and present possible solution approaches. Any transition towards sustainability can only be effective if far-reaching lifestyle changes complement technological advancements. However, existing societies, economies and cultures incite consumption expansion and the structural imperative for growth in competitive market economies inhibits necessary societal change. Current environmental impact mitigation neglects over-consumption from affluent citizens as a primary driver. The authors highlight the role of bottom-up movements to overcome structural economic growth imperatives spurring consumption by changing structures and culture towards safe and just systems.

Genome-wide association studies (GWAS) have laid the foundation for investigations into the biology of complex traits, drug development and clinical guidelines. However, the majority of discovery efforts are based on data from populations of European ancestry 1 – 3 . In light of the differential genetic architecture that is known to exist between populations, bias in representation can exacerbate existing disease and healthcare disparities. Critical variants may be missed if they have a low frequency or are completely absent in European populations, especially as the field shifts its attention towards rare variants, which are more likely to be population-specific 4 – 10 . Additionally, effect sizes and their derived risk prediction scores derived in one population may not accurately extrapolate to other populations 11 , 12 . Here we demonstrate the value of diverse, multi-ethnic participants in large-scale genomic studies. The Population Architecture using Genomics and Epidemiology (PAGE) study conducted a GWAS of 26 clinical and behavioural phenotypes in 49,839 non-European individuals. Using strategies tailored for analysis of multi-ethnic and admixed populations, we describe a framework for analysing diverse populations, identify 27 novel loci and 38 secondary signals at known loci, as well as replicate 1,444 GWAS catalogue associations across these traits. Our data show evidence of effect-size heterogeneity across ancestries for published GWAS associations, substantial benefits for fine-mapping using diverse cohorts and insights into clinical implications. In the United States—where minority populations have a disproportionately higher burden of chronic conditions 13 —the lack of representation of diverse populations in genetic research will result in inequitable access to precision medicine for those with the highest burden of disease. We strongly advocate for continued, large genome-wide efforts in diverse populations to maximize genetic discovery and reduce health disparities. Genetic analyses of ancestrally diverse populations show evidence of heterogeneity across ancestries and provide insights into clinical implications, highlighting the importance of including ancestrally diverse populations to maximize genetic discovery and reduce health disparities.

Electrolysis that reduces carbon dioxide (CO 2 ) to useful chemicals can, in principle, contribute to a more sustainable and carbon-neutral future 1 – 6 . However, it remains challenging to develop this into a robust process because efficient conversion typically requires alkaline conditions in which CO 2 precipitates as carbonate, and this limits carbon utilization and the stability of the system 7 – 12 . Strategies such as physical washing, pulsed operation and the use of dipolar membranes can partially alleviate these problems but do not fully resolve them 11 , 13 – 15 . CO 2 electrolysis in acid electrolyte, where carbonate does not form, has therefore been explored as an ultimately more workable solution 16 – 18 . Herein we develop a proton-exchange membrane system that reduces CO 2 to formic acid at a catalyst that is derived from waste lead–acid batteries and in which a lattice carbon activation mechanism contributes. When coupling CO 2 reduction with hydrogen oxidation, formic acid is produced with over 93% Faradaic efficiency. The system is compatible with start-up/shut-down processes, achieves nearly 91% single-pass conversion efficiency for CO 2 at a current density of 600 mA cm −2 and cell voltage of 2.2 V and is shown to operate continuously for more than 5,200 h. We expect that this exceptional performance, enabled by the use of a robust and efficient catalyst, stable three-phase interface and durable membrane, will help advance the development of carbon-neutral technologies. We develop a proton-exchange membrane system that reduces CO 2 to formic acid at a catalyst that is derived from waste lead–acid batteries and in which a lattice carbon activation mechanism contributes.

The late Miocene offers the opportunity to assess the sensitivity of the Earth’s climate to orbital forcing and to changing boundary conditions, such as ice volume and greenhouse gas concentrations, on a warmer-than-modern Earth. Here we investigate the relationships between low- and high-latitude climate variability in an extended succession from the subtropical northwestern Pacific Ocean. Our high-resolution benthic isotope record in combination with paired mixed layer isotope and Mg/Ca-derived temperature data reveal that a long-term cooling trend was synchronous with intensification of the Asian winter monsoon and strengthening of the biological pump from ~7 Ma until ~5.5 Ma. The climate shift occurred at the end of a global δ 13 C decrease, suggesting that changes in the carbon cycle involving the terrestrial and deep ocean carbon reservoirs were instrumental in driving late Miocene climate cooling. The inception of cooler climate conditions culminated with ephemeral Northern Hemisphere glaciations between 6.0 and 5.5 Ma. The late Miocene period allows investigation of climate-carbon cycle dynamics on a warmer-than-modern Earth. Here, the authors show that changes in the global carbon cycle drove climate cooling, culminating in ephemeral Northern Hemisphere glaciations and intensification of the Asian winter monsoon from 7 to 5.5 Ma.

Low soil moisture and high vapour pressure deficit (VPD) cause plant water stress and lead to a variety of drought responses, including a reduction in transpiration and photosynthesis 1 , 2 . When soils dry below critical soil moisture thresholds, ecosystems transition from energy to water limitation as stomata close to alleviate water stress 3 , 4 . However, the mechanisms behind these thresholds remain poorly defined at the ecosystem scale. Here, by analysing observations of critical soil moisture thresholds globally, we show the prominent role of soil texture in modulating the onset of ecosystem water limitation through the soil hydraulic conductivity curve, whose steepness increases with sand fraction. This clarifies how ecosystem sensitivity to VPD versus soil moisture is shaped by soil texture, with ecosystems in sandy soils being relatively more sensitive to soil drying, whereas ecosystems in clayey soils are relatively more sensitive to VPD. For the same reason, plants in sandy soils have limited potential to adjust to water limitations, which has an impact on how climate change affects terrestrial ecosystems. In summary, although vegetation–atmosphere exchanges are driven by atmospheric conditions and mediated by plant adjustments, their fate is ultimately dependent on the soil. Through their effects on soil hydraulic properties, soil texture and sand content are shown to have broad implications for the terrestrial water cycle and carbon sink, and specific implications for vital ecosystems that are vulnerable to drought, especially with changing climate.