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"Neoteny."
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Cuteness engineering : designing adorable products and services
This state of the art monograph presents a unique introduction to thinking about cuteness and its incorporation into modern, especially computer-based, products and services. Cuteness is defined and explored in relation to user-centered design concepts and methods, in addition to considering the history of cuteness and cuteness in other cultures, especially in relation to eastern Asia. The authors provide detailed analyses and histories of cuteness in Japan and in China, the rise of Kawaii and Moe culture artifacts, and their relation to social, psychological, and design issues. They also attempt an initial taxonomy of cuteness. Finally, detailed interviews with leading designers of cute products and services, such as Hello Kitty, provide an understanding of the philosophy and decision-making process of designers of cuteness. \"Cuteness Engineering: Designing Adorable Products and Services\" will be of interest and use to a wide range of professionals, researchers, academics, and students who are interested in exploring the world of cuteness in fresh new ways and gaining insights useful for their work and studies.
Book
Description of Ceratogeusis thamiresae new genus and species from Panama, the first Telegeusinae (Coleoptera, Elateroidea, Omethidae) with flabellate antennae
Ceratogeusis thamiresae Ferreira, gen. et sp. nov. , the first Telegeusinae with flabellate antennae, is described from Panama. The new genus and species is diagnosed and illustrated, and an updated key for the genera of Telegeusinae is given. The Telegeusinae genus Platydrilus López-Pérez & Zaragoza-Caballero, 2021, was discovered to be a junior homonym of Platydrilus Michaelsen, 1891 (Annelida, Oligochaeta, Eudrilidae), and therefore a pre-occupied name.
Journal Article
The restless brain: how intrinsic activity organizes brain function
Traditionally studies of brain function have focused on task-evoked responses. By their very nature such experiments tacitly encourage a reflexive view of brain function. While such an approach has been remarkably productive at all levels of neuroscience, it ignores the alternative possibility that brain functions are mainly intrinsic and ongoing, involving information processing for interpreting, responding to and predicting environmental demands. I suggest that the latter view best captures the essence of brain function, a position that accords well with the allocation of the brain's energy resources, its limited access to sensory information and a dynamic, intrinsic functional organization. The nature of this intrinsic activity, which exhibits a surprising level of organization with dimensions of both space and time, is revealed in the ongoing activity of the brain and its metabolism. As we look to the future, understanding the nature of this intrinsic activity will require integrating knowledge from cognitive and systems neuroscience with cellular and molecular neuroscience where ion channels, receptors, components of signal transduction and metabolic pathways are all in a constant state of flux. The reward for doing so will be a much better understanding of human behaviour in health and disease.
Journal Article
This book is cute
\"Information about why certain people, animals and things are considered \"cute\" and the scientific background, for children\"-- Provided by publisher.
Book
Types and Fecundity of Neotenic Reproductives Produced in 5-Year-Old Orphaned Colonies of the Drywood Termite, ICryptotermes domesticus/I
Orphaned colonies of Cryptotermes domesticus readily produce replacement reproductives and continue propagation. In this study, we aimed to investigate the production and fecundity of neotenic reproductives in 5-year-old colonies of C. domesticus after orphaning. All 15 experimental colonies were successfully re-established by the neotenic reproductive pair. Three types of neotenic reproductives with various wing-bud lengths were observed: type I with micro wing buds, type II with short wing buds, and type III with long wing buds. Four patterns of pairs made up of these neotenics, namely, type I + type II, type I + type III, type II + type II, and type II + type III, exhibited reproductive capacities similar to those of the primary reproductive pair. We speculated that these neotenic reproductives were derived from various nymphal instars. The 5-year-old colonies had three instars of nymphs, with the majority being in the second instar, followed by the first. Thus, the combination of neotenic reproductives with short wing buds and micro wing buds was the dominant differentiation pathway of the orphaned colonies. After the removal of the original primary reproductive pair, the nymphs matured into neotenic reproductives and took over reproduction in the colony in 107.40 ± 15.18 days. This study highlights the importance of quarantine and routine inspection of wood, as well as the significance of early prevention and control of C. domesticus infestation in wood. Moreover, this study confirms the high differentiation and reproductive capacities of C. domesticus.
Journal Article
Persistent metabolic youth in the aging female brain
Sex differences influence brain morphology and physiology during both development and aging. Here we apply a machine learning algorithm to a multiparametric brain PET imaging dataset acquired in a cohort of 20- to 82-year-old, cognitively normal adults (n = 205) to define their metabolic brain age. We find that throughout the adult life span the female brain has a persistently lower metabolic brain age—relative to their chronological age—compared with the male brain. The persistence of relatively younger metabolic brain age in females throughout adulthood suggests that development might in part influence sex differences in brain aging. Our results also demonstrate that trajectories of natural brain aging vary significantly among individuals and provide a method to measure this.
Journal Article
A cross-species proteomic map reveals neoteny of human synapse development
The molecular mechanisms and evolutionary changes accompanying synapse development are still poorly understood1,2. Here we generate a cross-species proteomic map of synapse development in the human, macaque and mouse neocortex. By tracking the changes of more than 1,000 postsynaptic density (PSD) proteins from midgestation to young adulthood, we find that PSD maturation in humans separates into three major phases that are dominated by distinct pathways. Cross-species comparisons reveal that human PSDs mature about two to three times slower than those of other species and contain higher levels of Rho guanine nucleotide exchange factors (RhoGEFs) in the perinatal period. Enhancement of RhoGEF signalling in human neurons delays morphological maturation of dendritic spines and functional maturation of synapses, potentially contributing to the neotenic traits of human brain development. In addition, PSD proteins can be divided into four modules that exert stage- and cell-type-specific functions, possibly explaining their differential associations with cognitive functions and diseases. Our proteomic map of synapse development provides a blueprint for studying the molecular basis and evolutionary changes of synapse maturation.
Journal Article
Extraordinary neoteny of synaptic spines in the human prefrontal cortex
The major mechanism for generating diversity of neuronal connections beyond their genetic determination is the activity-dependent stabilization and selective elimination of the initially overproduced synapses [Changeux JP, Danchin A (1976) Nature 264:705–712]. The largest number of supranumerary synapses has been recorded in the cerebral cortex of human and nonhuman primates. It is generally accepted that synaptic pruning in the cerebral cortex, including prefrontal areas, occurs at puberty and is completed during early adolescence [Huttenlocher PR, et al. (1979) Brain Res 163:195–205]. In the present study we analyzed synaptic spine density on the dendrites of layer IIIC cortico–cortical and layer V cortico–subcortical projecting pyramidal neurons in a large sample of human prefrontal cortices in subjects ranging in age from newborn to 91 y. We confirm that dendritic spine density in childhood exceeds adult values by two- to threefold and begins to decrease during puberty. However, we also obtained evidence that overproduction and developmental remodeling, including substantial elimination of synaptic spines, continues beyond adolescence and throughout the third decade of life before stabilizing at the adult level. Such an extraordinarily long phase of developmental reorganization of cortical neuronal circuitry has implications for understanding the effect of environmental impact on the development of human cognitive and emotional capacities as well as the late onset of human-specific neuropsychiatric disorders.
Journal Article
Reflections on the Role of Differentiation Processes in Forming Behavioral Phenotypes: Can These Processes Replace the Concepts of Plastic Phenotype and Reversible Plastic Phenotype?
This essay presents two lines of argument to suggest that the extension into adulthood of specific phenotypic differentiation processes, typical of early development, is fundamental to the evolution of cognition. The first of these two lines of argument is organized in three steps. The first step reviews various studies of human development, highlighting that it has slowed down throughout evolution compared to that of great apes. The second step explores the relationship between this slowed development and human cognition. The third step discusses evolutionary comparative analyses that show a correlation between the evolution of cognitive processes and developmental changes. The second line of argument examines concepts of phenotype. First, the concepts of phenotype are reviewed in correspondence to the two meanings of the word plasticity (i.e., as the ability to alternate or as the ability to shape), and it is concluded that all phenotypes —rigid, plastic, and reversible—fit the meaning of shaping. It is proposed that a phenotypical process can be seen as a continuous series of functional differentiations that occur at different times during the life of the organism and at different contextual points, both inside and outside the organism. Finally, a brief recapitulation is presented that is focused on supporting the formation of behavioral phenotypes as a sequence of differentiation processes shaping the environmental interactions from the most general to the most particular.
Journal Article