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Today, medical education is anachronistic. It remains largely governed by the Flexner model. Yet medical practice itself is in the midst of a transformation as significant as the one that stimulated the Flexner revolution in 1910. All aspects of medical education, from premedical requirements to clinical training, must also transform. Otherwise, tomorrow’s physicians will be ill prepared to deliver high-quality care.

Today, 800 million people are chronically hungry and yet there are many countries where more than 70% of the adult population is obese or overweight.Over the past two centuries, dietary issues in developing countries focused on the health consequences of malnutrition, especially stunting and wasting in children and anemia in women of childbearing age.More recently, the world's nutrition profile has changed from a situation where the prevalence of underweight was more than double that of obesity to one where more people are obese than underweight.Once a symptom of affluence, obesity and overweight are rising in low- and middle-income countries, particularly in urban areas, where the increase is fastest.