Catalogue Search | MBRL
Are you sure you want to remove the book from the shelf?
{{itemTitle}}
8,959
result(s) for
"Pathogenic microorganisms"
Sort by:
Microbial Resolution
Why the global health project to avert emerging microbes
continually fails
In 1989, a group of U.S. government scientists met to discuss
some surprising findings: new diseases were appearing around the
world, and viruses that they thought long vanquished were
resurfacing. Their appearance heralded a future perpetually
threatened by unforeseeable biological risks, sparking a new
concept of disease: the \"emerging microbe.\" With the Cold War
nearing its end, American scientists and security experts turned to
confront this new \"enemy,\" redirecting national security against
its risky horizons. In order to be fought, emerging microbes first
needed to be made perceptible; but how could something immaterial,
unknowable, and ever mutating be coaxed into visibility,
knowability, and operability?
Microbial Resolution charts the U.S.-led war on the
emerging microbe to show how their uncertain futures were
transformed into objects of global science and security. Moving
beyond familiar accounts that link scientific knowledge production
to optical practices of visualizing the invisible, Gloria Chan-Sook
Kim develops a theory of \"microbial resolution\" to analyze the
complex problematic that arises when dealing with these entities:
what can be seen when there is nothing to see? Through a syncretic
analysis of data mining, animal-tracking technologies, media
networks, computer-modeled futures, and global ecologies and
infrastructures, she shows how a visual impasse-the impossibility
of seeing microbial futures-forms the basis for new modes of
perceiving, knowing, and governing in the present.
Timely and thought provoking, Microbial Resolution
opens up the rich paradoxes, irreconcilabilities, and failures
inherent in this project and demonstrates how these tensions
profoundly animate twenty-first-century epistemologies, aesthetics,
affects, and ecologies.
eBook
I'm trying to love germs
Entertaining, eye-opening and educational, this deep dive into the microscopic world of germs discusses the microbes in and on our bodies that help us survive, the ones that don't and everything in between.
Book
BSL3 and BSL4 Agents: Epidemiology, Microbiology, and Practical Guidelines
In one handy book, this reference gathers all the necessary information on 14 of the most commonly used dangerous groups of pathogens in biosafety level 3 and 4 laboratories. All the chapters are uniformly structured, with a brief overview of the microbiology, pathology, epidemiology and detection methods for each group. In addition, a whole chapter is devoted to the special biosafety requirements, disinfection, decontamination protocols, accident literature and accident procedures, as well as treatment options for all the organisms. This chapter is clearly marked and easy to find when opening the book. Essential literature for the increasing number of BSL3 or BSL4 labs worldwide and for medical facilities intervening in the case of an incident.
eBook
Disposal and management of solid waste : pathogens and diseases
\"In developed countries wastewater and sewage sludge are disposed by means that reduce or minimize exposure by humans to disease organisms. Most municipal solid waste goes to landfills which have liners to protect ground water. Humans are often exposed to pathogens, resulting in serious diseases from the disposal of human and animal wastes. This book describes the various pathogens and diseases that can be found in solid waste and describes the means and opportunities for disposal and management of various solid waste materials\"-- Provided by publisher.
Book
Deadly companions : how microbes shaped our history
The story of human history has been inextricably entwined with the story of microbes. Combining tales of devastating epidemics with accessible science and fascinating history, Deadly Companions reveals how closely microbes have evolved with us over the millennia, shaping human culture through infection, disease, and deadly pandemic.
eBook
Clinical Predictors of Nontuberculous Mycobacteria Lung Disease and Coisolates of Potential Pathogenic Microorganisms in Noncystic Fibrosis Bronchiectasis
Abstract
Background
In bronchiectasis, nontuberculous mycobacteria (NTM) lung disease (NTM-LD) is a well-known coexisting infection. However, microorganism coisolates and clinical NTM-LD predictors are poorly studied.
Methods
Patients with bronchiectasis diagnosed by means of computed tomography between January 2017 and June 2020 were screened, using the date of computed tomography as the index date. Those with a major bronchiectasis diagnosis in ≥2 follow-up visits after the index date were enrolled in the study, and NTM-LD occurrence and its association with pneumonia and hospitalization within 1 year were analyzed.
Results
Of the 2717 participants, 79 (2.9%) had NTM-LD diagnosed. The factors associated with NTM-LD included hemoptysis, postinfectious bronchiectasis, a tree-in-bud score ≥2, a modified Reiff score ≥4, and chronic obstructive pulmonary disease (adjusted odds ratios, 1.80, 2.36, 1.78, 2.95, and 0.51, respectively). Compared with patients in the non-NTM group, those with NTM-LD had higher rates of hospitalization (15.9% vs 32.9%; P < .001) and pneumonia (9.8% vs 20.3%; P = .003). Pseudomonas aeruginosa was the most common microorganism in those with NTM-LD and those in the non-NTM group (10.1% vs 7.8%; P = .40). However, compared with those in the non-NTM group, Acinetobacter baumannii and Escherichia coli were more prevalent in patients with NTM-LD (0.7% vs 3.8% [P = .03%] and 1.0% vs 3.8% [P = .05], respectively).
Conclusions
Postinfectious bronchiectasis with hemoptysis, higher radiological involvement, and a tree-in-bud pattern were associated with NTM-LD risk. The rate of A baumannii and E coli coisolation was higher in bronchiectasis populations with NTM-LD.
Factors associated with nontuberculous mycobacteria lung disease (NTM-LD) included hemoptysis, postinfectious bronchiectasis, a greater radiological extent of bronchiectasis, and tree-in-bud. Acinetobacter baumannii and Escherichia coli were more prevalent in the NTM-LD than in the non-NTM group.
Journal Article
BioWatch PCR Assays
BioWatch is an air monitoring system deployed in jurisdictions around the country with the goal of detecting the presence of certain high risk pathogenic microorganisms. It relies on a network of federal and nonfederal collaborative relationships to be successful, and is one part of a larger array of disease surveillance, intelligence-gathering, and biomonitoring activities in support of public safety and health. The assays used in the BioWatch system to detect the presence of pathogens in collected samples rely on the technique of polymerase chain reaction (PCR) to sensitively and specifically amplify target nucleic acid sequences.
BioWatch PCR Assays evaluates and provides guidance on appropriate standards for the validation and verification of PCR tests and assays in order to ensure that adequate performance data are available to public health and other key decision makers with a sufficient confidence level to facilitate the public health response to a BioWatch Actionable Response. This report discusses principles of performance standards, reviews information from several existing guidance documents and standards that might be applicable to BioWatch, and discusses assay testing efforts that have occurred or are ongoing. BioWatch PCR Assays provides recommendations on general principles and approaches for a performance standard and validation framework to meet BioWatch's mission. The report also considers how developments in technology, particularly in multiplex PCR and next-generation sequencing, can contribute to the ability of the BioWatch program to meet current and future challenges.
This report has been determined to contain information exempt from disclosure under 5 U.S.C. 552(b). Section 15 of the Federal Advisory Committee Act provides that the National Academies shall make its final report available to the public unless the National Academies determines that the report would disclose matters described in one or more of the exemption provisions under the Freedom of Information Act (FOIA). In such case, the National Academies \"shall make public an abbreviated version of the report that does not disclose those matters.\" This unrestricted, abbreviated version of the report represents, in so far as possible, the committee's findings, recommendations, and other substantive material without disclosing materials described in 5 U.S.C. 552(b).
eBook
Gain-of-Function Research
On March 10-11, 2016, the National Academies of Sciences, Engineering, and Medicine held a public symposium on potential U.S. government policies for the oversight of gain-of- function (GOF) research. This was the Academies' second meeting held at the request of the U.S. government to provide a mechanism to engage the life sciences community and the broader public and solicit feedback on optimal approaches to ensure effective federal oversight of GOF research as part of a broader U.S. government deliberative process.
The first symposium, held in December 2014, examined the underlying scientific and technical questions surrounding the potential risks and benefits of GOF research involving pathogens with pandemic potential. The second symposium focused on discussion of the draft recommendations regarding GOF research of a Working Group of the National Science Advisory Board for Biosecurity. This report summarizes the key issues and ideas identified during the second symposium.
eBook