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The injuries suffered by soldiers during WWI were as varied as they were brutal. How could the human body suffer and often absorb such disparate traumas? Why might the same wound lead one soldier to die but allow another to recover? In The Human Body in the Age of Catastrophe, Stefanos Geroulanos and Todd Meyers uncover a fascinating story of how medical scientists came to conceptualize the body as an integrated yet brittle whole. Responding to the harrowing experience of the Great War, the medical community sought conceptual frameworks to understand bodily shock, brain injury, and the vast differences in patient responses they occasioned. Geroulanos and Meyers carefully trace how this emerging constellation of ideas became essential for thinking about integration, individuality, fragility, and collapse far beyond medicine: in fields as diverse as anthropology, political economy, psychoanalysis, and cybernetics. Moving effortlessly between the history of medicine and intellectual history, The Human Body in the Age of Catastrophe is an intriguing look into the conceptual underpinnings of the world the Great War ushered in.

This is the first comprehensive account of \"Anatomy in National Socialism\". Traces the gradual escalation of ethical transgressions in anatomy during National Socialism from the traditional anatomical work with the dead to human experimentation, and points to the need for vigilance against similar gradual ethical compromise in contemporary medical ethics. Demonstrates the manner in which anatomists became complicit in the complete annihilation of the perceived \"enemies\" of the Nazi-government. Demands the full reconstruction of the biographies and memorialization of Nazi-victims, whose bodies were used for anatomical purposes.

The diet and weight-loss industry is worth $66 billion – billion!! The estimated annual health care costs of obesity-related illness are 190 billion or nearly 21% of annual medical spending in the United States. But how did we get here? Is this a battle we can't win? What changes need to be made in order to scale back the incidence of obesity in the US, and, indeed, around the world? Here, Jonathan Engel reviews the sources of the problem and offers the science behind our modern propensity toward obesity. He offers a plan for helping address the problem, but admits that it is, indeed, an uphill battle. Nevertheless, given the magnitude of the costs in years of life and vigor lost, it is a battle worth fighting. Fat Nation is a social history of obesity in the United States since the second World War. In confronting this familiar topic from a historical perspective, Jonathan Engel attempts to show that obesity is a symptom of complex changes that have transpired over the past half century to our food, our living habits, our life patterns, our built environments, and our social interactions. He offers readers solid grounding in the known science underlying obesity (genetic set points, complex endocrine feedback loops, neurochemical messengering) but then makes the novel argument that obesity is a result of the interaction of our genes with our environment. That is, our bodies have always been programmed to become obese, but until recently never had the opportunity to do so. Now, with cheap calories ubiquitous (particularly in the form of sucrose), unwalkable physical spaces, deteriorating rituals and norms surrounding eating, and the withering of cooking skills, nearly every American daily confronts the challenge of not putting on weight. Given the outcomes, though, for those who are obese, Engel encourages us to address the problems and offers suggestions to help remedy the problem.

In the nineteenth century, infants were commonly breast-fed; by the middle of the twentieth century, women typically bottle-fed their babies on the advice of their doctors. In this book, Rima D. Apple discloses and analyzes the complex interactions of science, medicine, economics, and culture that underlie this dramatic shift in infant-care practices and women's lives. As infant feeding became the keystone of the emerging specialty of pediatrics in the twentieth century, the manufacture of infant food became a lucrative industry. More and more mothers reported difficulty in nursing their babies. While physicians were establishing themselves and the scientific experts and the infant-food industry was hawking the scientific bases of their products, women embraced \"scientific motherhood,\" believing that science could shape child care practices. The commercialization and medicalization of infant care established an environment that made bottle feeding not only less feared by many mothers, but indeed \"natural\" and \"necessary.\" Focusing on the history of infant feeding, this book clarifies the major elements involved in the complex and sometimes contradictory interaction between women and the medical profession, revealing much about the changing roles of mothers and physicians in American society. \"The strength of Apple's book is her ability to indicate how the mutual interests of mothers, doctors, and manufacturers led to the transformation of infant feeding. . . . Historians of science will be impressed with the way she probes the connections between the medical profession and the manufacturers and with her ability to demonstrate how medical theories were translated into medical practice.\"—Janet Golden, Isis

For modern scientists, history often starts with last week's journals and is regarded as largely a quaint interest compared with the advances of today. However, this book makes the case that, measured by major advances, the greatest decade in the history of brain studies was mid-twentieth century, especially the 1950s. The first to focus on worldwide contributions in this period, this book ranges through dozens of astonishing discoveries at all levels of the brain, from DNA (Watson and Crick), through growth factors (Hamburger and Levi-Montalcini), excitability (Hodgkin and Huxley), synapses (Katz and Eccles), dopamine and Parkinson's (Carlsson), visual processing (Hartline and Kuffler), the cortical column (Mountcastle), reticular activating system (Morruzzi and Magoun) and REM sleep (Aserinsky), to stress (Selye), learning (Hebb) and memory (HM and Milner). The clinical fields are also covered — from Cushing and Penfield, psychosurgery, and brain energy metabolism (Kety), to most of the major psychoactive drugs in use today (beginning with Delay and Deniker) — and much more. There is a focus on the creative process itself; on understanding how the combination of unique personalities, innovative hypotheses, and new methods led to the advances. Insight is given into this process through describing the struggles between male and female, student and mentor, academic and private sector, and the roles of chance and persistence. The book thus provides a multidisciplinary understanding of the revolution that created the modern field of neuroscience, and which set the bar for judging current and future advances.

Each year the Nobel Prizes in the natural sciences reveal amazing discoveries. New milestones in the relentless advance of science are identified. The growth of knowledge and its evolution can be researched in the Nobel archives where nominations are kept secret for 50 years after the awards have been made. They represent a treasure for real-time assessment of science. Norrby's earlier book, examined the unique archival records until 1959. The present book takes us up to 1962, surveying a range of dazzling discoveries. All prizes in immunology are reviewed. Their impact on our capacity to control infectious diseases and transplant organs are highlighted. The Nobel year 1962 is exceptional in recognizing the most major advance in biology since Darwin in 1859 presented his theory of evolution. This was the dramatic discovery of the double-helix structure of DNA by Watson and Crick in 1953. The era of molecular biology had begun. Its explosive development continues into the present.

With wit, insight, and earthy wisdom, a book that explores the nature of the self, the relationship between the brain and the heart, the gendering of our physical and emotional selves, and the struggle to accommodate mind and body, emotions and experience.

The anatomy of language has been investigated with PET or fMRI for more than 20 years. Here I attempt to provide an overview of the brain areas associated with heard speech, speech production and reading. The conclusions of many hundreds of studies were considered, grouped according to the type of processing, and reported in the order that they were published. Many findings have been replicated time and time again leading to some consistent and undisputable conclusions. These are summarised in an anatomical model that indicates the location of the language areas and the most consistent functions that have been assigned to them. The implications for cognitive models of language processing are also considered. In particular, a distinction can be made between processes that are localized to specific structures (e.g. sensory and motor processing) and processes where specialisation arises in the distributed pattern of activation over many different areas that each participate in multiple functions. For example, phonological processing of heard speech is supported by the functional integration of auditory processing and articulation; and orthographic processing is supported by the functional integration of visual processing, articulation and semantics. Future studies will undoubtedly be able to improve the spatial precision with which functional regions can be dissociated but the greatest challenge will be to understand how different brain regions interact with one another in their attempts to comprehend and produce language.

Early in the twentieth century, Walter B. Cannon (1871–1945) introduced his overarching hypothesis of “homeostasis” (Cannon 1932)—the ability to sustain physiological values within a narrow range necessary for life during periods of stress. Physical exercise represents a stress in which motor, respiratory and cardiovascular systems must be integrated across a range of metabolic stress to match oxygen delivery to oxygen need at the cellular level, together with appropriate thermoregulatory control, blood pressure adjustments and energy provision. Of these, blood pressure regulation is a complex but controlled variable, being the function of cardiac output and vascular resistance (or conductance). Key in understanding blood pressure control during exercise is the coordinating role of the autonomic nervous system. A long history outlines the development of these concepts and how they are integrated within the exercise context. This review focuses on the renaissance observations and thinking generated in the first three decades of the twentieth century that opened the doorway to new concepts of inquiry in cardiovascular regulation during exercise. The concepts addressed here include the following: (1) exercise and blood pressure, (2) central command, (3) neurovascular transduction with emphasis on the sympathetic nerve activity and the vascular end organ response, and (4) tonic neurovascular integration.