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Raspberry Pi For Dummies, 4th Edition
A recipe for having fun and getting things done with the Raspberry Pi The Raspberry Pi makes it easy to learn about computers and computer programming, and Raspberry Pi For Dummies makes it even easier! Using this extremely affordable and compact computer, you can learn to code in languages like Scratch and Python, explore how electronics work, create computer-generated buildings in Minecraft and music in Sonic Pic, become Linux-savvy, make Internet-of-Things devices, or just play around! This book gets you up and running on your Raspberry Pi, starting with setting it up, downloading the operating system, and using the desktop environment. Then, the only limit is your imagination! It doesn’t matter whether you have a Raspberry Pi 4, Raspberry Pi 400, Raspberry Pi Zero W or an older model: we’ve got you covered. Raspberry Pi For Dummies explores the latest technology—the Raspberry Pi 4 and 400, Scratch 3 programming language, new games bundled with the Raspberry Pi, and the hottest Add-Ons out there. This introductory guide is the perfect place to start if you want to get a taste of everything the Raspberry Pi can do! Set up your Raspberry Pi, install the operating system, and connect to the Internet Learn the basics of the Linux desktop and Linux shell so you can program, work, and play Use Python, Scratch, and Sonic Pi to write your first programs and make games and digital music Discover how circuits work hand-in-hand with your Pi If you want to make the most of the Raspberry Pi for school, work, or play, you’ll love this easy-to-read reference.
eBook
Raspberry Pi for dummies
In Raspberry Pi For Dummies, 3rd Edition veteran tech authors Sean McManus and Mike Cook make it easier than ever to get you up and running on your Raspberry Pi, from setting it up, downloading the operating system, and using the desktop environment to editing photos, playing music and videos, and programming with Scratch--and everything in between.
Book
GSTP1 and cancer: Expression, methylation, polymorphisms and signaling (Review)
Glutathione S-transferase Pi (GSTP1) is an isozyme encoded by the GST pi gene that plays an important regulatory role in detoxification, anti-oxidative damage, and the occurrence of various diseases. The aim of the present study was to review the association between the expression of GSTP1 and the development and treatment of various cancers, and discuss GSTP1 methylation in several malignant tumors, such as prostate, breast and lung cancer, as well as hepatocellular carcinoma; to review the association between polymorphism of the GSTP1 gene and various diseases; and to review the effects of GSTP1 on electrophilic oxidative stress, cell signal transduction, and the regulation of carcinogenic factors. Collectively, GSTP1 plays a major role in the development of various diseases.
Journal Article
Learn electronics with Raspberry Pi : physical computing with circuits, sensors, outputs, and projects
Learning electronics can be tremendous fun -- your first flashing LED circuit is a reason to celebrate! But where do you go from there, and how can you move into more challenging projects without spending a lot of money on proprietary kits? One excellent answer is Raspberry Pi. Raspberry Pi is everywhere, it's inexpensive, and it's a wonderful tool for teaching about electronics and programming. Learn Electronics with Raspberry Pi shows you how to make a variety of cool projects using the Pi with programming languages like Scratch and Python, with no experience necessary. You'll learn how the Pi works, how to work with Raspbian Linux on the Pi, and how to design and create electronic circuits. You'll then create projects like an arcade game, disco lights, and infrared transmitter, and an LCD display. You'll also learn how to control Minecraft's Steve with a joystick and how to build a Minecraft house with a Pi, and even how to control a LEGO train with a Pi. You'll even learn how to create your own robot, including how to solder and even design a printed circuit board! Learn how to design and build electronic circuits, and even how to make a PCB Learn how to make fun projects like an arcade game, a robot, and a Minecraft controller while learning about sensors and how devices talk to each other Get started programming the Pi with Scratch and Python.
Book
Pentagamavunon-1 (PGV-1) inhibits ROS metabolic enzymes and suppresses tumor cell growth by inducing M phase (prometaphase) arrest and cell senescence
We previously showed that curcumin, a phytopolyphenol found in turmeric (
Curcuma longa
), targets a series of enzymes in the ROS metabolic pathway, induces irreversible growth arrest, and causes apoptosis. In this study, we tested Pentagamavunon-1 (PGV-1), a molecule related to curcumin, for its inhibitory activity on tumor cells
in vitro
and
in vivo
. PGV-1 exhibited 60 times lower GI
50
compared to that of curcumin in K562 cells, and inhibited the proliferation of cell lines derived from leukemia, breast adenocarcinoma, cervical cancer, uterine cancer, and pancreatic cancer. The inhibition of growth by PGV-1 remained after its removal from the medium, which suggests that PGV-1 irreversibly prevents proliferation. PGV-1 specifically induced prometaphase arrest in the M phase of the cell cycle, and efficiently induced cell senescence and cell death by increasing intracellular ROS levels through inhibition of ROS-metabolic enzymes. In a xenograft mouse model, PGV-1 had marked anti-tumor activity with little side effects by oral administration, whereas curcumin rarely inhibited tumor formation by this administration. Therefore, PGV-1 is a potential therapeutic to induce tumor cell apoptosis with few side effects and low risk of relapse.
Journal Article
Targeting GSTP1 as Therapeutic Strategy against Lung Adenocarcinoma Stemness and Resistance to Tyrosine Kinase Inhibitors
Glutathione S‐transferase pi (GSTP1), a phase II detoxification enzyme, is known to be overexpressed and mediates chemotherapeutic resistance in lung cancer. However, whether GSTP1 supports cancer stem cells (CSCs) and the underlying mechanisms in lung adenocarcinoma (LUAD) remain largely unknown. This study unveiled that GSTP1 is upregulated in lung CSCs and supports tumor self‐renewal, metastasis, and resistance to targeted tyrosine kinase inhibitors of LUAD both in vitro and in vivo. Mechanistically, CaMK2A (calcium/calmodulin‐dependent protein kinase 2 isoform A)/NRF2 (nuclear factor erythroid 2‐related factor 2)/GSTP1 is uncovered as a regulatory axis under hypoxia. CaMK2A increased GSTP1 expression through phosphorylating the Sersine558 residue of NRF2 and promoting its nuclear translocation, a novel mechanism for NRF2 activation apart from conventional oxidization‐dependent activation. Upregulation of GSTP1 in turn suppressed reactive oxygen species levels and supported CSC phenotypes. Clinically, GSTP1 analyzed by immunohistochemistry is upregulated in a proportion of LUAD and serves as a prognostic marker for survival. Using patient‐derived organoids from an ALK‐translocated LUAD, the therapeutic potential of a specific GSTP1 inhibitor ezatiostat in combination treatment with the ALK inhibitor crizotinib is demonstrated. This study demonstrates GSTP1 to be a promising therapeutic target for long‐term control of LUAD through targeting CSCs. This study unveils the role of calcium/calmodulin‐‐depdendent protein kinase 2 isoform A (CaMK2A)/nuclear factor erythroid 2‐related factor (NRF2)/glutathione S‐transferase pi (GSTP1) axis under hypoxia in lung cancer stem cell maintenance. GSTP1 inhibitor Ezastiostat exhibits the potential as a combined treatment with tyrosine kinase inhibitor (TKI) to reverse TKI resistance, illustrating GSTP1 as promising therapeutic target for lung adenocarcinoma.
Journal Article
Learn robotics with Raspberry Pi : build and code your own moving, sensing, thinking robots
\"A beginner's guide to building and coding robots with the Raspberry Pi microcomputer. Each chapter teaches progressively complex lessons, from wireless control to line following, through detailed instructions and projects\"-- Provided by publisher.
Book
Raspberry Pi 3 Cookbook for Python Programmers
Raspberry Pi 3 is a tiny affordable chip used to learn and program through interactive projects. It has gained a lot of traction as the first choice in single-board computers due to its versatility. It extends a wide range of support to Python programming. This recipe-based guide will allow you to showcase the capabilities of Raspberry Pi 3.
eBook