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Iodine is a trace element that is required to produce thyroid hormone. Some preoperative skin antiseptics and contrast media that are used in a variety of specialties (eg, cardiovascular, urology) contain iodine. Clinicians and patients may believe that a history of a reaction to shellfish, povidone‐iodine, or radiopaque contrast media is an allergy requiring avoidance of all three substances. Because iodine is required for life and does not stimulate an immune response, there is no relationship between iodine and adverse reactions to iodine‐containing products. Perioperative nurses should have knowledge of allergies associated with iodine‐containing substances and should assess patients for allergies. During the assessment process, they can seek input on the cause of any previous reactions and share information on allergies with the patient. They also can collaborate with leaders and information technology personnel to update the electronic health record to avoid documentation of iodine as an allergen.

The unprecedented availability of 6-hourly data from a multi-model GCM ensemble in the CMIP5 data archive presents the new opportunity to dynamically downscale multiple GCMs to develop high-resolution climate projections relevant to detailed assessment of climate vulnerability and climate change impacts. This enables the development of high resolution projections derived from the same set of models that are used to characterise the range of future climate changes at the global and large-scale, and as assessed in the IPCC AR5. However, the technical and human resource required to dynamically-downscale the full CMIP5 ensemble are significant and not necessary if the aim is to develop scenarios covering a representative range of future climate conditions relevant to a climate change risk assessment. This paper illustrates a methodology for selecting from the available CMIP5 models in order to identify a set of 8–10 GCMs for use in regional climate change assessments. The selection focuses on their suitability across multiple regions—Southeast Asia, Europe and Africa. The selection (a) avoids the inclusion of the least realistic models for each region and (b) simultaneously captures the maximum possible range of changes in surface temperature and precipitation for three continental-scale regions. We find that, of the CMIP5 GCMs with 6-hourly fields available, three simulate the key regional aspects of climate sufficiently poorly that we consider the projections from those models ‘implausible’ ( MIROC - ESM, MIROC - ESM - CHEM, and IPSL - CM5B - LR ). From the remaining models, we demonstrate a selection methodology which avoids the poorest models by including them in the set only if their exclusion would significantly reduce the range of projections sampled. The result of this process is a set of models suitable for using to generate downscaled climate change information for a consistent multi-regional assessment of climate change impacts and adaptation.

The CORDEX-CORE initiative was developed with the aim of producing homogeneous regional climate model (RCM) projections over domains world wide. In its first phase, two RCMs were run at 0.22° resolution downscaling 3 global climate models (GCMs) from the CMIP5 program for 9 CORDEX domains and two climate scenarios, the RCP2.6 and RCP8.5. The CORDEX-CORE simulations along with the CMIP5 GCM ensemble and the most recently produced CMIP6 GCM ensemble are analyzed, with focus on several temperature, heat, wet and dry hazard indicators for present day and mid-century and far future time slices. The CORDEX-CORE ensemble shows a better performance than the driving GCMs for several hazard indices due to its higher spatial resolution. For the far future time slice the 3 ensembles project an increase in all temperature and heat indices analyzed under the RCP8.5 scenario. The largest increases are always shown by the CMIP6 ensemble, except for Tx > 35 °C, for which the CORDEX-CORE projects higher warming. Extreme wet and flood prone maxima are projected to increase by the RCM ensemble over the la Plata basin in South America, the Congo basin in Africa, east North America, north east Europe, India and Indochina, regions where a better performance is obtained, whereas the GCM ensembles show small or negligible signals. Compound hazard hotspots based on heat, drought and wet indicators are detected in each continent worldwide in region like Central America, the Amazon, the Mediterranean, South Africa and Australia, where a linear relation is shown between the heatwave and drought change signal, and region like Arabian peninsula, the central and south east Africa region (SEAF), the north west America (NWN), south east Asia, India, China and central and northern European regions (WCE, NEU) where the same linear relation is found for extreme precipitation and HW increases. Although still limited, the CORDEX-CORE initiative was able to produce high resolution climate projections with almost global coverage and can provide an important resource for impact assessment and climate service activities.

Six bias correction (BC) methods; delta-method (DT), linear scaling (LS), power transformation of precipitation (PTR), empirical quantile mapping (EQM), gamma quantile mapping (GQM) and gamma-pareto quantile mapping (GPQM) were applied to adjust the biases of historical monthly precipitation outputs from five General Circulation Models (GCMs) dynamically downscaled by two Regional Climate Models (RCMs) for a total of seven different GCM-RCM pairs over Costa Rica. High-resolution gridded precipitation observations were used for the control period 1951–1980 and validated over the period 1981–1995. Results show that considerable biases exist between uncorrected GCM-RCM outputs and observations, which largely depend on GCM-RCM pair, seasonality, climatic region and spatial resolution. After the application of bias correction, substantial biases reductions and comparable performances among most BC methods were observed for most GCM-RCM pairs; with EQM and DT marginally outperforming the remaining methods. Consequently, EQM and DT were selectively applied to correct the biases of precipitation projections from each individual GCM-RCM pair for a near-future (2011–2040), mid-future (2041–2070) and far-future (2071–2100) period under Representative Concentration Pathways (RCPs) 2.6, 4.5 and 8.5 using the control period 1961–1990. Results from the bias-corrected future ensemble-mean anticipate a marked decreasing trend in precipitation from near to far-future periods during the dry season (December, January, February (DJF) and March, April, May (MAM)) for RCP4.5 and 8.5; with pronounced drier conditions for those climatic regions draining towards the Pacific Ocean. In contrast, mostly wetter conditions are expected during the dry season under RCP2.6, particularly for the Caribbean region. In most of the country, the greatest decrease in precipitation is projected at the beginning of the rainy season (June, July, August (JJA)) for the far-future period under RCP8.5, except for the Caribbean region where mostly wetter conditions are anticipated. Regardless of future period, slight increases in precipitation with higher radiative forcing are expected for SON excluding the Caribbean region, where precipitation is likely to increase with increasing radiative forcing and future period. This study demonstrates that bias correction should be considered before direct application of GCM-RCM precipitation projections over complex territories such as Costa Rica.

This study aims to conduct a thorough investigation to compare the abilities of quantile mapping (QM) techniques as a bias correction method for the raw outputs from general circulation model (GCM)/regional climate model (RCM) combinations. The Karkheh River basin in Iran was selected as a case study, due to its diverse topographic features, to test the performances of the bias correction methods under different conditions. The outputs of two GCM/RCM combinations (ICHEC and NOAA-ESM) were acquired from the coordinated regional climate downscaling experiment (CORDEX) dataset for this study. The results indicated that the performances of the QMs varied, depending on the transformation functions, parameter sets, and topographic conditions. In some cases, the QMs' adjustments even made the GCM/RCM combinations' raw outputs worse. The result of this study suggested that apart from DIST, PTF:scale, and SSPLIN, the rest of the considered QM methods can provide relatively improved results for both rainfall and temperature variables. It should be noted that, according to the results obtained from the diverse topographic conditions of the sub-basins, the empirical quantiles (QUANT) and robust empirical quantiles (RQUANT) methods proved to be excellent options to correct the bias of rainfall data, while all bias correction methods, with the notable exceptions of performed PTF:scale and SSPLIN, performed relatively well for the temperature variable.

In hydrological climate-change impact studies, regional climate models (RCMs) are commonly used to transfer large-scale global climate model (GCM) data to smaller scales and to provide more detailed regional information. Due to systematic and random model errors, however, RCM simulations often show considerable deviations from observations. This has led to the development of a number of correction approaches that rely on the assumption that RCM errors do not change over time. It is in principle not possible to test whether this underlying assumption of error stationarity is actually fulfilled for future climate conditions. In this study, however, we demonstrate that it is possible to evaluate how well correction methods perform for conditions different from those used for calibration with the relatively simple differential split-sample test. For five Swedish catchments, precipitation and temperature simulations from 15 different RCMs driven by ERA40 (the 40 yr reanalysis product of the European Centre for Medium-Range Weather Forecasts (ECMWF)) were corrected with different commonly used bias correction methods. We then performed differential split-sample tests by dividing the data series into cold and warm respective dry and wet years. This enabled us to cross-evaluate the performance of different correction procedures under systematically varying climate conditions. The differential split-sample test identified major differences in the ability of the applied correction methods to reduce model errors and to cope with non-stationary biases. More advanced correction methods performed better, whereas large deviations remained for climate model simulations corrected with simpler approaches. Therefore, we question the use of simple correction methods such as the widely used delta-change approach and linear transformation for RCM-based climate-change impact studies. Instead, we recommend using higher-skill correction methods such as distribution mapping.

Science education researchers have developed a refined understanding of the structure of science teachers’ pedagogical content knowledge (PCK), but how to develop applicable and situation-adequate PCK remains largely unclear. A potential problem lies in the diverse conceptualisations of the PCK used in PCK research. This study sought to systematize existing science education research on PCK through the lens of the recently proposed refined consensus model (RCM) of PCK. In this review, the studies’ approaches to investigating PCK and selected findings were characterised and synthesised as an overview comparing research before and after the publication of the RCM. We found that the studies largely employed a qualitative case-study methodology that included specific PCK models and tools. However, in recent years, the studies focused increasingly on quantitative aspects. Furthermore, results of the reviewed studies can mostly be integrated into the RCM. We argue that the RCM can function as a meaningful theoretical lens for conceptualizing links between teaching practice and PCK development by proposing pedagogical reasoning as a mechanism and/or explanation for PCK development in the context of teaching practice.

The objective of this study was to evaluate the best performed bias correction methods to simulate the regional climate models for future climate change projections in Muger Subbasin. Delta change methods perform very well with a coefficient of correlation of 0.99 and a percent of bias –3. When we compare its corrected simulation result with observed data, the delta change method seems to have with no biases for maximum temperature, but increases by 1.67 °C from the mean for minimum temperature of 0.39 and 38.41 mm for monthly and annual precipitation, respectively. Delta change methods underestimate the model result for both temperature and precipitation. Linear scaling and variance scaling methods overestimate the maximum temperature of the simulation by 0.002 and 0.004 °C from the mean of the observed data, but it underestimates 1.59 and 1.56 °C the minimum temperature, respectively. The long-term temperature projection values (2060–2090) are higher than the near-term projections (2030–2060) for both RCP2.6 and RCP8.5 scenarios. Similarly, the change in annual precipitation for the long-term is higher than the near-term projections. As a conclusion, the results draw attention to the fact that bias-adjusted regional climate models data are crucial for the provision of local climate change impact studies in the Muger Subbasin.

Many studies bias correct daily precipitation from climate models to match the observed precipitation statistics, and the bias corrected data are then used for various modelling applications. This paper presents a review of recent methods used to bias correct precipitation from regional climate models (RCMs). The paper then assesses four bias correction methods applied to the weather research and forecasting (WRF) model simulated precipitation, and the follow-on impact on modelled runoff for eight catchments in southeast Australia. Overall, the best results are produced by either quantile mapping or a newly proposed two-state gamma distribution mapping method. However, the differences between the methods are small in the modelling experiments here (and as reported in the literature), mainly due to the substantial corrections required and inconsistent errors over time (non-stationarity). The errors in bias corrected precipitation are typically amplified in modelled runoff. The tested methods cannot overcome limitations of the RCM in simulating precipitation sequence, which affects runoff generation. Results further show that whereas bias correction does not seem to alter change signals in precipitation means, it can introduce additional uncertainty to change signals in high precipitation amounts and, consequently, in runoff. Future climate change impact studies need to take this into account when deciding whether to use raw or bias corrected RCM results. Nevertheless, RCMs will continue to improve and will become increasingly useful for hydrological applications as the bias in RCM simulations reduces.

This study examines the projected changes in the characteristics of the El Niño Southern Oscillation (ENSO) and Indian Ocean Dipole (IOD) in terms of mean state, intensity and frequency, and associated rainfall anomalies over eastern Africa. Two regional climate models driven by the same four global climate models (GCMs) and the corresponding GCM simulations are used to investigate projected changes in teleconnection patterns and East African rainfall. The period 1976–2005 is taken as the reference for present climate and the far-future climate (2070–2099) under Representative Concentration Pathway 8.5 (RCP8.5) is analyzed for projected change. Analyses of projections based on GCMs indicate an El Niño-like (positive IOD-like) warming pattern over the tropical Pacific (Indian) Ocean. However, large uncertainties remain in the projected future changes in ENSO/IOD frequency and intensity with some GCMs show increase of ENSO/IOD frequency and intensity, and others a decrease or no/small change. Projected changes in mean rainfall over eastern Africa based on the GCM and RCM data indicate a decrease in rainfall over most parts of the region during JJAS and MAM seasons, and an increase in rainfall over equatorial and southern part of the region during OND, with the greatest changes in equatorial region. During ENSO and IOD years, important changes in the strength of the teleconnections are found. During JJAS, when ENSO is an important driver of rainfall variability over the region, both GCM and RCM projections show an enhanced La Niña-related rainfall anomaly compared to the present period. Although the long rains (MAM) have little association with ENSO in the reference period, both GCMs and RCMs project stronger ENSO teleconnections in the future. On the other hand, during the short rains (OND), a dipole future change in rainfall teleconnection associated with ENSO and IOD is found, with a stronger ENSO/IOD related rainfall anomaly over the eastern part of the domain, but a weaker ENSO/IOD signal over the southern part of the region. This signal is consistent and robust in all global and regional model simulations. The projected increase in OND rainfall over the eastern horn of Africa might be linked with the mean changes in SST over Indian and Pacific Ocean basins and the associated Walker circulations.