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"Research Highlight"
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Fructose takes a detour to feed cancer
The mechanisms by which dietary fructose promotes tumour progression have remained poorly understood. A recent study published in
Nature
reveals that dietary fructose is metabolized in the liver, resulting in elevated circulating lipid levels that can serve as building blocks for cancer cells outside the liver.
Journal Article
Omicron, the great escape artist
Less than a month after the sequence of the SARS-CoV-2 Omicron variant was first announced, a number of articles in Nature and Cell examine its immune evasion characteristics.
Journal Article
Aspirin helps T cells to stop cancer spread
Drugs like aspirin can enhance the anti-metastatic activity of T cells by blocking a platelet-mediated pathway of suppression.
Journal Article
HDAC9 association with heart disease linked to NLRP3 inflammasome activation
Loss of a conserved
cis
-regulatory element at
HDAC9
increases NLRP3 inflammasome activation and may explain why
HDAC9
is a major risk locus for cardiovascular disease.
Journal Article
Transposon-derived decoy fine-tunes IFN responses
A transposon-derived isoform of the type I interferon (IFN) receptor IFNAR2 can serve as a decoy receptor to regulate IFN signalling.
Journal Article