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This superb guide brings the work of Filippo Coarelli, one of the most widely published and well-known scholars of Roman topography, archeology and art, to a broad English-language audience. Conveniently organized by walking tours and illustrated throughout with clear maps, drawings, and plans,'Rome and environs: an archaeological guide' covers all of the major, and an unparalleled number of minor, ancient sites in the city, and, unlike most other guides of Rome, includes major and many minor sites within easy reach of the city, such as Ostia Antica, Palestrina, Tivoli, and the many areas of interest along the ancient Roman roads.

The essay summarizes the data collected in a research, which is still in progress, conducted by the Tempi Moderni study centre on the condition of the Rom communities in Italy. It is based on two fundamental theses. First of all, on the fact that the system of inequalities experienced by Rom people is multidimensional. These dimensions influence each other on a material level and turn the relationship between cause and effect, legitimising widespread prejudice and discrimination against the Rom community. These prejudices are reconstructed also from a historical point of view, and the essay focuses mainly on employment and housing inequality. The second thesis analyzes the system of complex disparities affecting Rom communities within the system of inequalities and discriminations typical of Italian and global society. Inequality, poverty and work segregation are therefore the consequences of political choices aimed at marginalizing the numerous Rom communities and legitimizing widespread and dangerous commonplaces and prejudices.

Background Ginger contains gingerols, shogaols, paradols, gingerdiones, and terpenes which have shown to display anti-inflammatory properties and inhibit pain receptors. For this reason, ginger has been marketed as a natural ingredient for joint health.Purpose To determine whether ginger supplementation affects joint flexibility, health markers, and/or perceptions about quality of life (QOL) in individuals with mild-to-moderate joint pain.Methods Thirty men and women (56.0 ± 9.0 years, 164.4 ± 14 cm, 86.5 ± 20.9 kg, 31.0 ± 7.5 kg/m2) with a history of mild-to-severe joint and muscle pain and inflammation participated in a randomized, placebo-controlled, parallel-arm, intervention trial. Participants donated fasting blood, completed questionnaires, rated pain in the thighs to standardized pressure, and then completed 3 × 10 repetitions of squats/deep knee bends while holding 30% of body mass on days 0, 30, and 56 of supplementation. Participants repeated tests after 2 days of recovery following each testing session. Blood samples were evaluated for clinical markers of safety. Knee and hip range of motion (ROM) was assessed via goniometry, while low back flexibility was assessed via a sit-and-reach test. The short form health survey version 2 (SF-36) was administered to evaluate participant’s subjective perceptions of QOL. Participants were matched by age, sex, and body mass for double-blind and to ingest 125 mg/d of a placebo or ginger (GingerT3®, Specnova LLC, Tysons Corner, Virginia), standardized to contain 10% total gingerols and no more than 3% total shogaols for 58 days. Data were analyzed using the general linear model (GLM) analysis of variance with repeated measures, mean changes from baseline with 95% confidence intervals, and chi-squared analysis.Results Knee ROM tended to be higher in the ginger group (p = 0.063, ηp2 = 0.118) and at the end of the study (Day 56: 20.8 ° [−1.6, 43.2], p = 0.068; Day 58: 9.4 ° [−1.9, 20.7], p = 0.10). No significant interaction effects were observed in sit-and-reach results (p = 0.798, ηp2 = 0.013). Eosinophil values tended to increase over time in the ginger group (p = 0.009, ηp2 = 0.130), with significantly higher eosinophil levels observed after 58 days (p = 0.05), although still within normal ranges. The low-density lipoprotein (LDL) to high-density lipoprotein (HDL) ratio and total cholesterol:HDL ratio tended to increase over time in the ginger group after 56 days of supplementation with differences observed between groups in cholesterol (22.1 mg/dL [−4.3, 48.3], p = 0.096), LDL cholesterol (25.3 mg/dl [0.1, 50.6], p = 0.049), non-HDL cholesterol (26.5 mg/dL [−1.1, 53.7], p = 0.060), and the LDL:HDL ratio (0.64 [−.05, 1.3], p = 0.068), in part because baseline values were generally higher in the ginger group. However, values were well within normal limits for healthy individuals. When evaluating changes from baseline, the difference in the LDL:HDL ratio was the only significant difference between groups (0.37 [0.004, 0.73], p = 0.048), while the ratio of CHL:HDL tended to be higher (0.40 [−0.03, 0.83], p = 0.067) with ginger supplementation. Pairwise comparisons revealed that fasting blood glucose values were lower in the ginger group after 56 (−11.5 mg/dL [−25.1, 2.0], p = 0.092) and 58 (−13.8 mg/dL [−26.1, −1.6], p = 0.028) days. All blood values remained within normal clinical ranges. Chi-squared analysis of the SF-36 QOL responses revealed significant differences between group ratings of health compared to 1 year ago, including reducing the volume of time allocated to work and other activities, experiencing bodily pain over the last 4 weeks, feeling full of life, and anticipating their health to worsen. Perceptions tended to differ between groups when asked to rate whether health limits lifting of carrying of groceries, physical health results in accomplishing less than they would like, physical health limiting the kind of work/activities, cutting down on time spent on work or other activities, and feeling nervous, happy, tired, healthy as anybody, and that health was excellent. A total of 73.3% participants in the placebo group reported using rescue doses of analgesics, while 46.7% participants in the ginger group reported taking analgesics. However, the chi-squared analysis did not reveal significant differences in the number of participants reporting the use of rescue doses of analgesics during baseline testing (χ2 p = 0.195), after 4 weeks (χ2 p = 0.232), and after 8 weeks of supplementation (χ2 p = 0.713). Participants typically rated side effects as infrequent (1–2 times/week) and of minimal to slight severity. However, there was some evidence that participants in the ginger group reported more frequent and severe headaches, heart palpitations, and nervousness.Conclusion Ginger supplementation appears to be well tolerated and have some favorable effects on knee ROM, markers of health and perceptions about QOL and may reduce use of over-the-counter analgesics in individuals with mild-to-moderate joint pain. Registered clinical trial #ISRCTN74292348.

There is growing interest in the development of transient, multiphysics models for nuclear reactors and analysis of uncertainties in those models. Reduced-order models (ROMs) provide a computationally cheaper alternative to compute uncertainties. However, the application of ROMs to transient systems remains a challenging task. Here, a 1-D, twogroup, time-dependent, diffusion model was used to explore the potential of three different ROMs: the intrusive POD-Galerkin and DMD-Galerkin methods and the purely datadriven DMD. For the problem studied, POD-Galerkin exhibited by far the best accuracy and was selected for further application to uncertainty propagation. Perturbations were introduced to the initial condition and to the cross-section data. A greedy-POD sampling procedure was used to construct a reduced space that captured much of the variation in the uncertain these parameters. Results indicate that relatively few samples of the uncertain parameters are needed to produce a basis for POD-Galerkin that leads to distributions of the quantities of interest that match well with those obtained from the full-order model using brute-force, forward sampling.

This superb guide brings the work of Filippo Coarelli, one of the most widely published and well-known scholars of Roman topography, archeology and art, to a broad English-language audience. Conveniently organized by walking tours and illustrated throughout with clear maps, drawings, and plans, Rome and Environs: An Archaeological Guide covers all of the major, and an unparalleled number of minor, ancient sites in the city, and, unlike most other guides of Rome, includes major and many minor sites within easy reach of the city, such as Ostia Antica, Palestrina, Tivoli, and the many areas of interest along the ancient Roman roads. An essential resource for tourists interested in a deeper understanding of Rome's classical remains, it is also the ideal book for students and scholars approaching the ancient history of one of the world's most fascinating cities. • Covers all the major sites including the Capitoline, the Roman Forum, the Imperial Fora, the Palatine Hill, the Valley of the Colosseum, the Esquiline, the Caelian, the Quirinal, and the Campus Martius. • Discusses important clusters of sites-one on the area surrounding Circus Maximus and the other in the vicinity of the Trastevere, including the Aventine and the Vatican. • Covers the history and development of the city walls and aqueducts. • Follows major highways leading outside of the city to important and fascinating sites in the periphery of Rome. • Features 189 maps, drawings, and diagrams, and an appendix on building materials and techniques. • Includes an updated and expanded bibliography for students and scholars of Ancient Rome.

\"Humanist collaborators also contributed to the development of visual projects in many ways. That they served as advisors and propagandists is well known, but we have scant knowledge of exactly how they worked with artists, and especially with architects. How did their ideas make their way into form? The role of the humanist advisor has been studied primarily in respect to the representational media of painting and sculpture, focusing on so-called iconographic programs or inventions; but their role in architectural projects is much less understood\"-- Provided by publisher.

(1) Background: Measuring joint range of motion has traditionally occurred with a universal goniometer or expensive laboratory based kinematic analysis systems. Technological advances in wearable inertial measurement units (IMU) enables limb motion to be measured with a small portable electronic device. This paper aims to validate an IMU, the ‘Biokin’, for measuring shoulder range of motion in healthy adults; (2) Methods: Thirty participants completed four shoulder movements (forward flexion, abduction, and internal and external rotation) on each shoulder. Each movement was assessed with a goniometer and the IMU by two testers independently. The extent of agreement between each tester’s goniometer and IMU measurements was assessed with intra-class correlation coefficients (ICC) and Bland-Altman 95% limits of agreement (LOA). Secondary analysis compared agreement between tester’s goniometer or IMU measurements (inter-rater reliability) using ICC’s and LOA; (3) Results: Goniometer and IMU measurements for all movements showed high levels of agreement when taken by the same tester; ICCs > 0.90 and LOAs < ±5 degrees. Inter-rater reliability was lower; ICCs ranged between 0.71 to 0.89 and LOAs were outside a prior defined acceptable LOAs (i.e., > ±5 degrees); (4) Conclusions: The current study provides preliminary evidence of the concurrent validity of the Biokin IMU for assessing shoulder movements, but only when a single tester took measurements. Further testing of the Biokin’s psychometric properties is required before it can be confidently used in routine clinical practice and research settings.