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22,708,764 result(s) for "Science"
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National Geographic science of everything : how things work in our world : from cell phones, soap bubbles & vaccines to GPS, x-rays & submarines
\"This book explains the science behind all the machines, gadgets, systems, and processes we take for granted. The perfect book for techies--young or old, male or female--who read Popular Science and Wired or watch \"How It Works\" and \"How It's Made.\"
Shaky Foundations
Numerous popular and scholarly accounts have exposed the deep impact of patrons on the production of scientific knowledge and its applications.Shaky Foundationsprovides the first extensive examination of a new patronage system for the social sciences that emerged in the early Cold War years and took more definite shape during the 1950s and early 1960s, a period of enormous expansion in American social science. By focusing on the military, the Ford Foundation, and the National Science Foundation, Mark Solovey shows how this patronage system presented social scientists and other interested parties, including natural scientists and politicians, with new opportunities to work out the scientific identity, social implications, and public policy uses of academic social research. Solovey also examines significant criticisms of the new patronage system, which contributed to widespread efforts to rethink and reshape the politics-patronage-social science nexus starting in the mid-1960s. Based on extensive archival research,Shaky Foundationsaddresses fundamental questions about the intellectual foundations of the social sciences, their relationships with the natural sciences and the humanities, and the political and ideological import of academic social inquiry.
Taking the metabolic pulse of the world’s coral reefs
Worldwide, coral reef ecosystems are experiencing increasing pressure from a variety of anthropogenic perturbations including ocean warming and acidification, increased sedimentation, eutrophication, and overfishing, which could shift reefs to a condition of net calcium carbonate (CaCO3) dissolution and erosion. Herein, we determine the net calcification potential and the relative balance of net organic carbon metabolism (net community production; NCP) and net inorganic carbon metabolism (net community calcification; NCC) within 23 coral reef locations across the globe. In light of these results, we consider the suitability of using these two metrics developed from total alkalinity (TA) and dissolved inorganic carbon (DIC) measurements collected on different spatiotemporal scales to monitor coral reef biogeochemistry under anthropogenic change. All reefs in this study were net calcifying for the majority of observations as inferred from alkalinity depletion relative to offshore, although occasional observations of net dissolution occurred at most locations. However, reefs with lower net calcification potential (i.e., lower TA depletion) could shift towards net dissolution sooner than reefs with a higher potential. The percent influence of organic carbon fluxes on total changes in dissolved inorganic carbon (DIC) (i.e., NCP compared to the sum of NCP and NCC) ranged from 32% to 88% and reflected inherent biogeochemical differences between reefs. Reefs with the largest relative percentage of NCP experienced the largest variability in seawater pH for a given change in DIC, which is directly related to the reefs ability to elevate or suppress local pH relative to the open ocean. This work highlights the value of measuring coral reef carbonate chemistry when evaluating their susceptibility to ongoing global environmental change and offers a baseline from which to guide future conservation efforts aimed at preserving these valuable ecosystems.
The tree of knowledge : the bright and the dark sides of science
This text traces the history of science and details two divergent futures: one in which science accelerates the downfall of Homo sapiens and another in which it helps our species engage in a new and positive adventure, whose outcome nobody can know.
Organic phosphorus in the terrestrial environment: a perspective on the state of the art and future priorities
Background The dynamics of phosphorus (P) in the environment is important for regulating nutrient cycles in natural and managed ecosystems and an integral part in assessing biological resilience against environmental change. Organic P (Po) compounds play key roles in biological and ecosystems function in the terrestrial environment being critical to cell function, growth and reproduction. Scope We asked a group of experts to consider the global issues associated with Po in the terrestrial environment, methodological strengths and weaknesses, benefits to be gained from understanding the Po cycle, and to set priorities for Po research. Conclusions We identified seven key opportunities for Po research including: the need for integrated, quality controlled and functionally based methodologies; assessment of stoichiometry with other elements in organic matter; understanding the dynamics of Po in natural and managed systems; the role of microorganisms in controlling Po cycles; the implications of nanoparticles in the environment and the need for better modelling and communication of the research. Each priority is discussed and a statement of intent for the Po research community is made that highlights there are key contributions to be made toward understanding biogeochemical cycles, dynamics and function of natural ecosystems and the management of agricultural systems.
Unbelievable science : stuff that will blow your mind
\"From space to technology, the natural world to health and well-being, this fascinating book introduces you to the science behind today's most interesting headlines\"--Back cover.
Long-term thermal sensitivity of Earth’s tropical forests
The sensitivity of tropical forest carbon to climate is a key uncertainty in predicting global climate change. Although short-term drying and warming are known to affect forests, it is unknown if such effects translate into long-term responses. Here, we analyze 590 permanent plots measured across the tropics to derive the equilibrium climate controls on forest carbon. Maximum temperature is the most important predictor of aboveground biomass (−9.1 megagrams of carbon per hectare per degree Celsius), primarily by reducing woody productivity, and has a greater impact per °C in the hottest forests (>32.2°C). Our results nevertheless reveal greater thermal resilience than observations of short-term variation imply. To realize the long-term climate adaptation potential of tropical forests requires both protecting them and stabilizing Earth’s climate.
Timelines of science
\"Follow the story of science year by year with [an] ... illustrated timeline with ... explanations of key scientific theories and concepts; identify the influential thinkers behind revolutionary breakthroughs and discover how they changed the world; trace the development of landmark innovations such as the measurement of time, computers, and mobile communication; see major advances and achievements in their broader context\"-- Provided by publisher.
Airway surface liquid acidification initiates host defense abnormalities in Cystic Fibrosis
Cystic fibrosis (CF) is caused by defective Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein. Morbidity is mainly due to early airway infection. We hypothesized that S. aureus clearance during the first hours of infection was impaired in CF human Airway Surface Liquid (ASL) because of a lowered pH. The ASL pH of human bronchial epithelial cell lines and primary respiratory cells from healthy controls (WT) and patients with CF was measured with a pH microelectrode. The antimicrobial capacity of airway cells was studied after S. aureus apical infection by counting surviving bacteria. ASL was significantly more acidic in CF than in WT respiratory cells. This was consistent with a defect in bicarbonate secretion involving CFTR and SLC26A4 (pendrin) and a persistent proton secretion by ATP12A. ASL demonstrated a defect in S. aureus clearance which was improved by pH normalization. Pendrin inhibition in WT airways recapitulated the CF airway defect and increased S. aureus proliferation. ATP12A inhibition by ouabain decreased bacterial proliferation. Antimicrobial peptides LL-37 and hBD1 demonstrated a pH-dependent activity. Normalizing ASL pH might improve innate airway defense in newborns with CF during onset of S. aureus infection. Pendrin activation and ATP12A inhibition could represent novel therapeutic strategies to normalize pH in CF airways.