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Strain hardening, elongation, and shearing speed effects of flow behaviors on coil-rod shearing during automatic multi-stage cold forging (AMSCF) are experimentally investigated. AMSCF machines and an experimental apparatus with a universal testing machine are utilized. Various coil materials are tested, including A6061-T6, SWCH10A, SCM435, and SCM415. The former is used to investigate the elongation and shearing speed effects on the sheared surface features. The latter is used to reveal the dependence of shearing phenomena on strain hardening and elongation. The new findings show the strong dependence of coil-rod shearing phenomena and surface features on flow behaviors and shearing speed. They will lead the engineers to the optimized shearing process design.

Nanometric probes based on surface-enhanced Raman scattering (SERS) are promising candidates for all-optical environmental, biological and technological sensing applications with intrinsic quantitative molecular specificity. However, the effectiveness of SERS probes depends on a delicate trade-off between particle size, stability and brightness that has so far hindered their wide application in SERS imaging methodologies. In this Article, we introduce holographic Raman microscopy, which allows single-shot three-dimensional single-particle localization. We validate our approach by simultaneously performing Fourier transform Raman spectroscopy of individual SERS nanoparticles and Raman holography, using shearing interferometry to extract both the phase and the amplitude of wide-field Raman images and ultimately localize and track single SERS nanoparticles inside living cells in three dimensions. Our results represent a step towards multiplexed single-shot three-dimensional concentration mapping in many different scenarios, including live cell and tissue interrogation and complex anti-counterfeiting applications.Holography of incoherent emission from SERS probes allows multiplexed single-particle localization in three dimensions in one shot using a wide-field microscope.

The increasing demand for sustainable and cost-effective manufacturing solutions has led to the development of innovative approaches to enhance the durability and reliability of cutting tools. This study presents a novel method for manufacturing shearing tools utilizing interchangeable modular elements loaded by deposition welding with covered electrodes. Using Weibull distribution modeling, a comparative reliability analysis between conventionally manufactured shear tools and the proposed modular design demonstrates a significant increase in the mean time to failure (MTTF). The least squares method (LSM) estimation was used in order to determine the shearing tools’ lifetime, expressed by reliability indices. Experimental results confirm that the modular tools achieve more than double the lifetime of traditional counterparts, with improved resistance to wear and mechanical stress. These findings highlight the potential for widespread industrial application, optimizing tool performance and sustainability in manufacturing processes.

Despite decades of technological advancements in blood-contacting medical devices, complications related to shear flow-induced blood trauma are still frequently observed in clinic. Blood trauma includes haemolysis, platelet activation, and degradation of High Molecular Weight von Willebrand Factor (HMW vWF) multimers, all of which are dependent on the exposure time and magnitude of shear stress. Specifically, accumulating evidence supports that when blood is exposed to shear stresses above a certain threshold, blood trauma ensues; however, it remains unclear how various constituents of blood are affected by discrete shears experimentally. The aim of this study was to expose blood to discrete shear stresses and evaluate blood trauma indices that reflect red cell, platelet, and vWF structure. Citrated human whole blood (n = 6) was collected and its haematocrit was adjusted to 30 ± 2% by adding either phosphate buffered saline (PBS) or polyvinylpyrrolidone (PVP). Viscosity of whole blood was adjusted to 3.0, 12.5, 22.5 and 37.5 mPa·s to yield stresses of 3, 6, 9, 12, 50, 90 and 150 Pa in a custom-developed shearing system. Blood samples were exposed to shear for 0, 300, 600 and 900 s. Haemolysis was measured using spectrophotometry, platelet activation using flow cytometry, and HMW vWF multimer degradation was quantified with gel electrophoresis and immunoblotting. For tolerance to 300, 600 and 900 s of exposure time, the critical threshold of haemolysis was reached after blood was exposed to 90 Pa for 600 s (P < 0.05), platelet activation and HMW vWF multimer degradation were 50 Pa for 600 s and 12 Pa for 300 s respectively (P < 0.05). Our experimental results provide simultaneous comparison of blood trauma indices and thus also the relation between shear duration and magnitude required to induce damage to red cells, platelets, and vWF. Our results also demonstrate that near-physiological shear stress (<12 Pa) is needed in order to completely avoid any form of blood trauma. Therefore, there is an urgent need to design low shear-flow medical devices in order to avoid blood trauma in this blood-contacting medical device field.

When granular assemblies are subject to external loads or displacements, particles interact with each other through contact and may exhibit translations and rotations. From a micromechanical perspective, particle rotations are an essential mechanism influencing the macroscopic behavior of granular materials. In this study, biaxial shearing tests were conducted on assemblies of dual-sized circular particles at different confining pressures. A high-precision image analysis method was developed to extract the particle-level motion of all the particles, including the rotational behavior. Experimental results showed that most of the particles exhibited rotations. Particles within the shear band exhibited more significant rotations and were characterized by low connectivity (number of contacts per particle). In contrast, the particles outside the shear band rotated lesser, only in the beginning stage of shearing. Every rotation in either direction is accompanied by an opposite rotation of almost the same magnitude in the neighboring region, and rotation clusters have been observed. Rotations in both directions are normally distributed within the assembly, and the average particle rotation is zero. The average rotations in both directions evolve symmetrically with major principal strain. Generally, the rotation rate (degrees per incremental strain) is observed to be maximum at the start of the shearing, and gradually it becomes constant toward the end of the shearing. The average value of the absolute cumulative rotation observed for whole particles is 18.6° at the end of shearing, i.e., 20% deviatoric strain. Smaller size particles tend to exhibit 67% higher rotations than bigger particles. Confining pressures have no significant effect on the rotational behavior of circular particles.

Zwitterionic hydrogels exhibit eminent nonfouling and hemocompatibility. Several key challenges hinder their application as coating materials for blood-contacting biomedical devices, including weak mechanical strength and low adhesion to the substrate. Here, we report a poly(carboxybetaine) microgel reinforced poly(sulfobetaine) (pCBM/pSB) pure zwitterionic hydrogel with excellent mechanical robustness and anti-swelling properties. The pCBM/pSB hydrogel coating was bonded to the PVC substrate via the entanglement network between the pSB and PVC chain. Moreover, the pCBM/pSB hydrogel coating can maintain favorable stability even after 21 d PBS shearing, 0.5 h strong water flushing, 1000 underwater bends, and 100 sandpaper abrasions. Notably, the pCBM/pSB hydrogel coated PVC tubing can not only mitigate the foreign body response but also prevent thrombus formation ex vivo in rats and rabbits blood circulation without anticoagulants. This work provides new insights to guide the design of pure zwitterionic hydrogel coatings for biomedical devices. Zwitterionic hydrogels are nonfouling and hemocompatibility but several key challenges such as weak mechanical strength and low adhesion hamper their application as coating materials for devices. Here, the authors report a microgel reinforced zwitterionic hydrogel with excellent mechanical robustness and anti-swelling properties.

With consumer electronics transitioning toward flexible products, there is a growing need for high-performance, mechanically robust, and inexpensive transparent conductors (TCs) for optoelectronic device integration. Herein, we report the scalable fabrication of highly conductive poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) thin films via solution shearing. Specific control over deposition conditions allows for tunable phase separation and preferential PEDOT backbone alignment, resulting in record-high electrical conductivities of 4,600 ± 100 S/cm while maintaining high optical transparency. High-performance solution-sheared TC PEDOT:PSS films were used as patterned electrodes in capacitive touch sensors and organic photovoltaics to demonstrate practical viability in optoelectronic applications.

Microturbulence can produce stationary fine-scale radial corrugations on the plasma density and temperature gradients in magnetic confinement fusion devices. We study the effect of these corrugations, focusing on electron temperature gradient (ETG) transport in the tokamak pedestal, and report three main findings. 1) In the presence of a sinusoidal background temperature gradient corrugation, each ETG mode splits into three distinct eigenvalues, with one being the original, one being more unstable and one being less unstable. 2) Despite the presence of more unstable linear modes, nonlinear gyrokinetic simulations show a significant reduction in fluxes. 3) Profile shearing associated with the fine-scale background corrugations is identified as the saturation mechanism explaining the reduction in fluxes. It originates from the radial variation of the mode’s own phase velocity (proportional to the local diamagnetic drift velocity and the pressure gradient), and not from externally generated flows or E × B zonal flows. Fine-scale profile shearing could be a ubiquitous turbulence saturation mechanism in fusion plasmas.

The streaming instability (SI) is a leading candidate for planetesimal formation, which can concentrate solids through two-way aerodynamic interactions with the gas. The resulting concentrations can become sufficiently dense to collapse under particle self-gravity, forming planetesimals. Previous studies have carried out large parameter surveys to establish the critical particle to gas surface density ratio (Z), above which SI-induced concentration triggers planetesimal formation. The threshold Z depends on the dimensionless stopping time (τ s , a proxy for dust size). However, these studies neglected both particle self-gravity and external turbulence. Here, we perform 3D stratified shearing box simulations with both particle self-gravity and turbulent forcing, which we characterize via a turbulent diffusion parameter, α D. We find that forced turbulence, at amplitudes plausibly present in some protoplanetary disks, can increase the threshold Z by up to an order of magnitude. For example, for τ s = 0.01, planetesimal formation occurs when Z ≳ 0.06, ≳0.1, and ≳0.2 at α D = 10−4, 10−3.5, and 10−3, respectively. We provide a single fit to the critical Z required for the SI to work as a function of α D and τ s (although limited to the range τ s = 0.01–0.1). Our simulations also show that planetesimal formation requires a mid-plane particle-to-gas density ratio that exceeds unity, with the critical value being largely insensitive to α D. Finally, we provide an estimation of particle scale height that accounts for both particle feedback and external turbulence.

Holding a shell in their hands, one can apply six loads: three by pulling and shearing, and three by bending and twisting. Here, it is shown that the shell will resist exactly three load cases and comply with the other three, provided the shell is simply connected, meaning it has no holes and no handles.