Catalogue Search | MBRL
Are you sure you want to remove the book from the shelf?
{{itemTitle}}
836
result(s) for
"Small groups Case studies."
Sort by:
The lost boys : inside Muzafer Sherif's Robbers Cave experiment
\"Competition. Prejudice. Discrimination. Conflict. In 1954, a group of American boys attended a remote summer camp where they were split into two groups, and encouraged to bully, harass, and demonize each other. The results would make history as one of social psychology's classic studies, and most controversial, studies: the Robbers Cave experiment. Conducted at the height of the Cold War, officially the experiment had a happy ending: the boys reconciled, and psychologist Muzafer Sherif demonstrated that while hatred and violence are powerful forces, so too are cooperation and harmony. Today it is proffered as proof that under the right conditions warring groups can make peace. Yet the true story of the experiments is far more complex, and more chilling. In The Lost Boys, Gina Perry explores the experiment and its consequences, tracing the story of Sherif, a troubled outsider who struggled to craft an experiment that would vanquish his personal demons. Drawing on archival material and new interviews, Perry pieces together a story of drama, mutiny, and intrigue that has never been told before\"-- Provided by publisher.
Book
The Robbers Cave experiment : intergroup conflict and cooperation
Originally issued in 1954 and updated in 1961 and 1987, this pioneering study of small group conflict and cooperation has long been out-of-print. It is now available, in cloth and paper, with a new introduction by Donald Campbell, and a new postscript by O.J. Harvey.
In this famous experiment, one of the earliest in inter-group relationships, two dozen twelve-year-old boys in summer camp were formed into two groups, the Rattlers and the Eagles, and induced first to become militantly ethnocentric, then intensely cooperative. Friction and stereotyping were stimulated by a tug-of-war, by frustrations perceived to be caused by the out group, and by separation from the others. Harmony was stimulated by close contact between previously hostile groups and by the introduction of goals that neither group could meet alone. The experiment demonstrated that conflict and enmity between groups can be transformed into cooperation and vice versa and that circumstances, goals, and external manipulation can alter behavior.
Some have seen the findings of the experiment as having implications for reduction of hostility among racial and ethnic groups and among nations, while recognizing the difficulty of control of larger groups.
eBook
Robbers Cave Experiment: Intergroup Conflict and Cooperation. Orig. pub. as Intergroup Conflict and Group Relations
Originally issued in 1954 and updated in 1961 and 1987, this pioneering study of \"small group\" conflict and cooperation has long been out-of-print. It is now available, in cloth and paper, with a new introduction by Donald Campbell, and a new postscript by O.J. Harvey.In this famous experiment, one of the earliest in inter-group relationships, two dozen twelve-year-old boys in summer camp were formed into two groups, the Rattlers and the Eagles, and induced first to become militantly ethnocentric, then intensely cooperative. Friction and stereotyping were stimulated by a tug-of-war, by frustrations perceived to be caused by the \"out\" group, and by separation from the others. Harmony was stimulated by close contact between previously hostile groups and by the introduction of goals that neither group could meet alone. The experiment demonstrated that conflict and enmity between groups can be transformed into cooperation and vice versa and that circumstances, goals, and external manipulation can alter behavior.Some have seen the findings of the experiment as having implications for reduction of hostility among racial and ethnic groups and among nations, while recognizing the difficulty of control of larger groups.
eBook
Gene Expression-Based Classification of Non-Small Cell Lung Carcinomas and Survival Prediction
Current clinical therapy of non-small cell lung cancer depends on histo-pathological classification. This approach poorly predicts clinical outcome for individual patients. Gene expression profiling holds promise to improve clinical stratification, thus paving the way for individualized therapy.
A genome-wide gene expression analysis was performed on a cohort of 91 patients. We used 91 tumor- and 65 adjacent normal lung tissue samples. We defined sets of predictor genes (probe sets) with the expression profiles. The power of predictor genes was evaluated using an independent cohort of 96 non-small cell lung cancer- and 6 normal lung samples. We identified a tumor signature of 5 genes that aggregates the 156 tumor and normal samples into the expected groups. We also identified a histology signature of 75 genes, which classifies the samples in the major histological subtypes of non-small cell lung cancer. Correlation analysis identified 17 genes which showed the best association with post-surgery survival time. This signature was used for stratification of all patients in two risk groups. Kaplan-Meier survival curves show that the two groups display a significant difference in post-surgery survival time (p = 5.6E-6). The performance of the signatures was validated using a patient cohort of similar size (Duke University, n = 96). Compared to previously published prognostic signatures for NSCLC, the 17 gene signature performed well on these two cohorts.
The gene signatures identified are promising tools for histo-pathological classification of non-small cell lung cancer, and may improve the prediction of clinical outcome.
Journal Article
Structure, function and regulation of the hsp90 machinery
Heat shock protein 90 (Hsp90) is an ATP-dependent molecular chaperone which is essential in eukaryotes. It is required for the activation and stabilization of a wide variety of client proteins and many of them are involved in important cellular pathways. Since Hsp90 affects numerous physiological processes such as signal transduction, intracellular transport, and protein degradation, it became an interesting target for cancer therapy. Structurally, Hsp90 is a flexible dimeric protein composed of three different domains which adopt structurally distinct conformations. ATP binding triggers directionality in these conformational changes and leads to a more compact state. To achieve its function, Hsp90 works together with a large group of cofactors, termed co-chaperones. Co-chaperones form defined binary or ternary complexes with Hsp90, which facilitate the maturation of client proteins. In addition, posttranslational modifications of Hsp90, such as phosphorylation and acetylation, provide another level of regulation. They influence the conformational cycle, co-chaperone interaction, and inter-domain communications. In this review, we discuss the recent progress made in understanding the Hsp90 machinery.
Journal Article
Vaccine Effectiveness of JYNNEOS against Mpox Disease in the United States
In the United States, more than 30,000 cases of mpox (formerly known as monkeypox) had occurred as of March 1, 2023, in an outbreak disproportionately affecting transgender persons and gay, bisexual, and other men who have sex with men. In 2019, the JYNNEOS vaccine was approved for subcutaneous administration (0.5 ml per dose) to prevent mpox infection. On August 9, 2022, an emergency use authorization was issued for intradermal administration (0.1 ml per dose); however, real-world effectiveness data are limited for either route.
We conducted a case-control study based on data from Cosmos, a nationwide Epic electronic health record (EHR) database, to assess the effectiveness of JYNNEOS vaccination in preventing medically attended mpox disease among adults. Case patients had an mpox diagnosis code or positive orthopoxvirus or mpox virus laboratory result, and control patients had an incident diagnosis of human immunodeficiency virus (HIV) infection or a new or refill order for preexposure prophylaxis against HIV infection between August 15, 2022, and November 19, 2022. Odds ratios and 95% confidence intervals were estimated from conditional logistic-regression models, adjusted for confounders; vaccine effectiveness was calculated as (1 - odds ratio for vaccination in case patients vs. controls) × 100.
Among 2193 case patients and 8319 control patients, 25 case patients and 335 control patients received two doses (full vaccination), among whom the estimated adjusted vaccine effectiveness was 66.0% (95% confidence interval [CI], 47.4 to 78.1), and 146 case patients and 1000 control patients received one dose (partial vaccination), among whom the estimated adjusted vaccine effectiveness was 35.8% (95% CI, 22.1 to 47.1).
In this study using nationwide EHR data, patients with mpox were less likely to have received one or two doses of JYNNEOS vaccine than control patients. The findings suggest that JYNNEOS vaccine was effective in preventing mpox disease, and a two-dose series appeared to provide better protection. (Funded by the Centers for Disease Control and Prevention and Epic Research.).
Journal Article
Unveiling the influence of social network characteristics on sustainable performance in small and medium-sized enterprises: A dynamic capabilities perspective
Gaining a deeper understanding of the mechanism through which social networks influence sustainable performance and exploring the role of resource bricolage in enhancing competitiveness are valuable. These insights can help small and medium-sized enterprises (SMEs) better adapt to market changes in the digital age and ultimately, this can enable SMEs to achieve sustainable development. In the context of accelerated technological change and resource scarcity, the question of how SMEs can leverage network resources to achieve sustainable growth has become a pressing issue. This study, grounded in social network theory and resource-based theory, develops a theoretical model exploring the relationships between social network characteristics, resource bricolage, and SME sustainable performance. Using survey data from 230 SMEs, the study empirically demonstrates that both social network scale and social network strength have significant positive impacts on sustainable performance. Additionally, resource bricolage mediates the effects of social network scale and strength on SME performance. Moreover, opportunity identification and opportunity exploitation-key dimensions of dynamic capabilities—moderate the relationship between resource bricolage and sustainable performance. This study highlights the mechanisms through which SMEs can leverage social networks to enhance their sustainable performance, offering theoretical guidance for effectively identifying and utilizing network resources in uncertain and dynamic environments.
Journal Article
Evaluating the integrated reporting journey: insights, gaps and agendas for future research
PurposeThe purpose of this paper is to identify key challenges, opportunities, strengths and weaknesses experienced by the integrated reporting (IR) idea since the International Integrated Reporting Council (IIRC)’s Discussion Paper was published in late 2011. It provides insights into the phases of the IR journey as investigated by accounting researchers, identifies important gaps in the literature and sketches an agenda for future research.Design/methodology/approachThe paper develops a theoretically informed analysis of published IR research articles using the idea journey theoretical framework. The paper draws upon academic analysis and insights published in 65 IR-related articles across 83 accounting journals listed in the Scopus database.FindingsA key insight of the paper is that the academic literature has not yet covered all stages of the IR idea journey. The highest proportion of articles provide insights in the generation and production phases of this journey, while there is relatively little research into the impact phase of the IR idea. Furthermore, the locus of research covered by the current IR literature is situated at macro- and meso-levels. This reveals opportunities for future research to explore, at a more detailed level, interactions between single individuals or small groups in implementing or understanding the IR idea.Research limitations/implicationsThis paper focuses on the idea journey of the IIRC’s version of IR. It identifies gaps regarding the stages of the IR idea journey that have not been covered by the extant academic literature and suggests some research areas that need to be addressed to help inform improvements in policy and practice. A key limitation is that it draws on a single communication channel, namely, academic articles published in accounting journals, but it provides opportunities for considerable further developments.Originality/valueThe paper extends IR research by reconciling insights from an understandably fragmented emerging literature. It provides a multi-dimensional perspective on IR, highlighting the dynamics and interrelationships in the literature. It also helps inform improvements in research, policy and practice by identifying gaps regarding the stages of the IR idea journey that have not been covered by the extant academic literature. Lastly, the paper builds on the work of innovation and creativity scholars showing how the idea journey framework can be used to shape and add coherence to accounting research.
Journal Article
BRAPH: A graph theory software for the analysis of brain connectivity
The brain is a large-scale complex network whose workings rely on the interaction between its various regions. In the past few years, the organization of the human brain network has been studied extensively using concepts from graph theory, where the brain is represented as a set of nodes connected by edges. This representation of the brain as a connectome can be used to assess important measures that reflect its topological architecture. We have developed a freeware MatLab-based software (BRAPH-BRain Analysis using graPH theory) for connectivity analysis of brain networks derived from structural magnetic resonance imaging (MRI), functional MRI (fMRI), positron emission tomography (PET) and electroencephalogram (EEG) data. BRAPH allows building connectivity matrices, calculating global and local network measures, performing non-parametric permutations for group comparisons, assessing the modules in the network, and comparing the results to random networks. By contrast to other toolboxes, it allows performing longitudinal comparisons of the same patients across different points in time. Furthermore, even though a user-friendly interface is provided, the architecture of the program is modular (object-oriented) so that it can be easily expanded and customized. To demonstrate the abilities of BRAPH, we performed structural and functional graph theory analyses in two separate studies. In the first study, using MRI data, we assessed the differences in global and nodal network topology in healthy controls, patients with amnestic mild cognitive impairment, and patients with Alzheimer's disease. In the second study, using resting-state fMRI data, we compared healthy controls and Parkinson's patients with mild cognitive impairment.
Journal Article
Climate change adaptation strategies of small-scale farmers in Ngamiland East, Botswana
Climate change and variability threaten the sustainability of agricultural and food production, especially in agrarian communities. In Southern Africa, rainfall is expected to decline by almost 10% by the year 2050 and the largest increase in temperature can be experienced. Despite the potential risks of climate change on agricultural productivity, Botswana does not have a dedicated policy to respond to climate change. Furthermore, there is a dearth of research done in Botswana to provide an understanding of factors that shape farmers’ adaptation to climate change and institutional link to the adaptive capacity of farming households. Therefore, the aim of this article is to analyse institutions that influence farmers’ adaptation strategies of farmers in Botswana, using Ngamiland East as a case study. The paper relies on empirical data collected from purposively selected key informants and 300 households. The results show that the majority of farmers who have climate variability adaptation strategies in place are largely influenced by indigenous knowledge. Women and low-income earners are less likely to employ climate change adaptation strategies in order to improve their agricultural productivity. This article gives a better perspective of the strengths, weaknesses, opportunities and threats facing institutions designed to enable agricultural productivity. It recommends that macro-level and local government institutions should acknowledge the indigenous knowledge, community-level institutions and farmers’ adaptive capacity in policy formulation processes.
Journal Article