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"Snipers."
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Reaper : ghost target
\"The explosive new thriller series written by Nicholas Irving, the New York Times bestselling author of The Reaper and star of Fox's American Grit. American hero, or unhinged vigilante? In Reaper: Ghost Target, Vick \"The Reaper\" Harwood is an esteemed sniper with a record kill count--33 kills in 90 days--when he is knocked out under mortar attack in Afghanistan. He wakes up back in the United States with little memory of what happened, his spotter and gun both unrecovered from the battlefield. Harwood has resigned himself to slowly picking up the pieces of his life, training Special Forces snipers in Fort Bragg, North Carolina, and starting a promising relationship with an Olympic medalist named Jackie. But when a series of assassinations start occurring in the area, Harwood can't explain why he just happens to be nearby for each killing--or how a sniper rifle that matches the description of the one he lost seems to be involved. His memory of the past few days is hazy and full of blackouts, and even he has to wonder, is he being framed? Or is he the killer? As Harwood runs from the authorities, his girlfriend falls off the radar, his missing spotter resurfaces, and the assassinated men are outed as drug and sex traffickers. Nothing is adding up. Harwood realizes he has to unravel this mystery, and fast, or find himself paying the ultimate price for crimes he may not have committed\"-- Provided by publisher.
Book
Billy Summers : a novel
\"Billy Summers is a killer for hire. He's among the best snipers in the world, a decorated Iraq war vet who can blend into any neighbourhood and vanish after the shot is taken. But he will only agree to the contract if the target is a truly bad guy. And now Billy wants out. But first he's offered one final job - an offer which is just too big to refuse. Billy is given a fake identity as a writer, and a high-rise office from which to make the kill. But as the days count down to the hit, Billy becomes convinced that something about the job is wrong. He does not yet know just how wrong, or about the woman who will help him try to set things right.\" -- Back cover.
WHO DO OUR METHODS SERVE AND PROTECT?
Introductory courses in Christian ethics ordinarily survey deontological, teleological, and virtue ethics, testing each against case studies. In spring 2021, this author followed the customary approach, but our case was a claim made by Sgt. John Mattingly of Louisville Metro Police Department, who was involved in the killing of Breonna Taylor. In an e-mail to over 1,000 LMPD colleagues, Mattingly claimed, \"I know we did the legal, moral and ethical thing that night.\" Mattingly's striking assertion raises epistemological and meta-ethical questions. In what sense was killing Ms. Taylor the right thing to do? Was this action virtuous? Did it proceed from a worthy intention toward a valid goal? Was it done in accordance with duty/ies? Did it produce good consequences? Was it conducive toward liberation? While the methods are necessary, none is fully adequate; the article argues that they should be supplemented by responsibilist ethical lenses adapted from Darryl Trimiew and Iris Marion Young.
Journal Article
Game of snipers
\"When Bob Lee Swagger is approached by a woman who lost a son to war and has spent the years since risking all that she has to find the sniper who pulled the trigger, he knows right away he'll do everything in his power to help her. But what begins as a favor becomes an obsession, and soon Swagger is back in the action, teaming up with the Mossad, the FBI, and local American law enforcement as he tracks a sniper who is his own equal ... and attempts to decipher that assassin's ultimate target before it's too late.\"-- Provided by publisher.
Book
Target: Alex Cross
\"A leader has fallen, and the procession route from Capitol Hill to the White House is lined with hundreds of thousands of mourners. None feel the loss of a President more keenly than Alex Cross, who has devoted his life to the public good. A sniper's bullet strikes a target in the heart of DC. Alex Cross's wife, Bree Stone, newly elevated chief of DC detectives, faces an ultimatum: solve the case, or lose the position for which she's worked her entire career for. The Secret Service and the FBI deploy as well in the race to find the shooter. Cross is tasked by the new President to take a personal role with the FBI, leading an investigation unprecedented in scale and scope. Cross has a horrible premonition that the sniper's strike is only the beginning of a larger attack\"-- Provided by publisher.
Book
Recent Advances in Genome-Editing Technology with CRISPR/Cas9 Variants and Stimuli-Responsive Targeting Approaches within Tumor Cells: A Future Perspective of Cancer Management
The innovative advances in transforming clustered regularly interspaced short palindromic repeats-associated protein 9 (CRISPR/Cas9) into different variants have taken the art of genome-editing specificity to new heights. Allosteric modulation of Cas9-targeting specificity by sgRNA sequence alterations and protospacer adjacent motif (PAM) modifications have been a good lesson to learn about specificity and activity scores in different Cas9 variants. Some of the high-fidelity Cas9 variants have been ranked as Sniper-Cas9, eSpCas9 (1.1), SpCas9-HF1, HypaCas9, xCas9, and evoCas9. However, the selection of an ideal Cas9 variant for a given target sequence remains a challenging task. A safe and efficient delivery system for the CRISPR/Cas9 complex at tumor target sites faces considerable challenges, and nanotechnology-based stimuli-responsive delivery approaches have significantly contributed to cancer management. Recent innovations in nanoformulation design, such as pH, glutathione (GSH), photo, thermal, and magnetic responsive systems, have modernized the art of CRISPR/Cas9 delivery approaches. These nanoformulations possess enhanced cellular internalization, endosomal membrane disruption/bypass, and controlled release. In this review, we aim to elaborate on different CRISPR/Cas9 variants and advances in stimuli-responsive nanoformulations for the specific delivery of this endonuclease system. Furthermore, the critical constraints of this endonuclease system on clinical translations towards the management of cancer and prospects are described.
Journal Article