Explore the vast range of titles available.

Recently, microalgal biotechnology has received increasing interests in producing valuable, sustainable and environmentally friendly bioproducts. The development of economically viable production processes entails resolving certain limitations of microalgal biotechnology, and fast evolving genetic engineering technologies have emerged as new tools to overcome these limitations. This review provides a synopsis of recent progress, current trends and emerging approaches of genetic engineering of microalgae for commercial applications, including production of pharmaceutical protein, lipid, carotenoids and biohydrogen, etc. Photochemistry improvement in microalgae and CO2 sequestration by microalgae via genetic engineering were also discussed since these subjects are closely entangled with commercial production of the above mentioned products. Although genetic engineering of microalgae is proved to be very effective in boosting performance of production in laboratory conditions, only limited success was achieved to be applicable to industry so far. With genetic engineering technologies advancing rapidly and intensive investigations going on, more bioproducts are expected to be produced by genetically modified microalgae and even much more to be prospected.

Aspergillosis complicating severe influenza infection has been increasingly detected worldwide. Recently, coronavirus disease-associated pulmonary aspergillosis (CAPA) has been detected through rapid reports, primarily from centers in Europe. We provide a case series of CAPA, adding 20 cases to the literature, with review of pathophysiology, diagnosis, and outcomes. The syndromes of pulmonary aspergillosis complicating severe viral infections are distinct from classic invasive aspergillosis, which is recognized most frequently in persons with neutropenia and in other immunocompromised persons. Combined with severe viral infection, aspergillosis comprises a constellation of airway-invasive and angio-invasive disease and results in risks associated with poor airway fungus clearance and killing, including virus- or inflammation-associated epithelial damage, systemic immunosuppression, and underlying lung disease. Radiologic abnormalities can vary, reflecting different pathologies. Prospective studies reporting poor outcomes in CAPA patients underscore the urgent need for strategies to improve diagnosis, prevention, and therapy.

Nitrogen heterocycles are essential parts of the chemical machinery of life and often reveal intriguing structures. They are not only widespread in terrestrial habitats but can also frequently be found as natural products in the marine environment. This review highlights the important class of marine pyrrole alkaloids, well-known for their diverse biological activities. A broad overview of the marine pyrrole alkaloids with a focus on their isolation, biological activities, chemical synthesis, and derivatization covering the decade from 2010 to 2020 is provided. With relevant structural subclasses categorized, this review shall provide a clear and timely synopsis of this area.

Cnidarians have been known since ancient times for the painful stings they induce to humans. The effects of the stings range from skin irritation to cardiotoxicity and can result in death of human beings. The noxious effects of cnidarian venoms have stimulated the definition of their composition and their activity. Despite this interest, only a limited number of compounds extracted from cnidarian venoms have been identified and defined in detail. Venoms extracted from Anthozoa are likely the most studied, while venoms from Cubozoa attract research interests due to their lethal effects on humans. The investigation of cnidarian venoms has benefited in very recent times by the application of omics approaches. In this review, we propose an updated synopsis of the toxins identified in the venoms of the main classes of Cnidaria (Hydrozoa, Scyphozoa, Cubozoa, Staurozoa and Anthozoa). We have attempted to consider most of the available information, including a summary of the most recent results from omics and biotechnological studies, with the aim to define the state of the art in the field and provide a background for future research.

Fisheries bycatch is one of the biggest threats to marine mammal populations. A literature review was undertaken to provide a comprehensive assessment and synopsis of gear modifications and technical devices to reduce marine mammal bycatch in commercial trawl, purse seine, longline, gillnet and pot/trap fisheries. Successfully implemented mitigation measures include acoustic deterrent devices (pingers) which reduced the bycatch of some small cetacean species in gillnets, appropriately designed exclusion devices which reduced pinniped bycatch in some trawl fisheries, and various pot/trap guard designs that reduced marine mammal entrapment. However, substantial development and research of mitigation options is required to address the bycatch of a range of species in many fisheries. No reliably effective technical solutions to reduce small cetacean bycatch in trawl nets are available, although loud pingers have shown potential. There are currently no technical options that effectively reduce marine mammal interactions in longline fisheries, although development of catch and hook protection devices is promising. Solutions are also needed for species, particularly pinnipeds and small cetaceans, that are not deterred by pingers and continue to be caught in static gillnets. Large whale entanglements in static gear, particularly buoy lines for pots/traps, needs urgent attention although there is encouraging research on rope-less pot/trap systems and identification of rope colours that are more detectable to whale species. Future mitigation development and deployment requires rigorous scientific testing to determine if significant bycatch reduction has been achieved, as well as consideration of potentially conflicting mitigation outcomes if multiple species are impacted by a fishery.

The southern part of the West African Craton includes the Baoulé-Mossi Domain, the world’s premier Paleoproterozoic gold province (~10,000 metric ton gold endowment). Structural, metamorphic, and geochronological data suggest gold mineralisation occurred during three episodes that span much of the Eoeburnean and Eburnean orogenic cycles. Eoeburnean orogenic and rare skarn-hosted gold deposits formed between ca. 2200 and 2135 Ma during repeated episodes of volcanism, plutonism, and shortening, which thickened the Paleoproterozoic crust. Early Eburnean orogenic and placer gold deposits formed between ca. 2110 and 2095 Ma during inversion, metamorphism, and subsequent oblique shortening of intra-orogenic basins filled after ca. 2135 Ma. This episode of mineralisation terminated when the Baoulé-Mossi Domain docked with the Archean Kénéma-Man Domain at ca. 2095 Ma. Late Eburnean orogenic and less common intrusion-related gold deposits formed between ca. 2095 and 2060 Ma during strike-slip to oblique-slip tectonics, post-collisional high-K plutonism and crustal reworking across the western and southern Baoulé-Mossi Domain. Eoeburnean gold deposits include ca. 10 % of the gold endowment of the Baoulé-Mossi Domain, whereas the Early Eburnean and Late Eburnean deposits include ca. 50–70% and 20–40%, respectively. Here, we highlight the favourable confluence of accretion-collision tectonics, involving juvenile crust formation as well as protracted magmatic, metamorphic, and deformation histories that resulted in diachronous gold events spread over at least 100 myr throughout the Baoulé-Mossi Domain.

With the increase in video surveillance data, techniques such as video synopsis are being used to construct small videos for analysis, thereby saving storage resources. The video synopsis framework applies in real-time environments, allowing for the creation of synopsis between multiple and single-view cameras; the same framework encompasses optimization, extraction, and object detection algorithms. Contemporary state-of-the-art synopsis frameworks are suitable only for particular scenarios. This paper aims to review the traditional state-of-the-art video synopsis techniques and understand the different methods incorporated in the methodology. A comprehensive review provides analysis of varying video synopsis frameworks and their components, along with insightful evidence for classifying these techniques. We primarily investigate studies based on single-view and multiview cameras, providing a synopsis and taxonomy based on their characteristics, then identifying and briefly discussing the most commonly used datasets and evaluation metrics. At each stage of the synopsis framework, we present new trends and open challenges based on the obtained insights. Finally, we evaluate the different components such as object detection, tracking, optimization, and stitching techniques on a publicly available dataset and identify the lacuna among the different algorithms based on experimental results.