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5,586 result(s) for "Technology Humor."
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How to win friends and influence fungi : collected quirks of science, tech, engineering, and math from nerd nite
\"In the vein of acclaimed popular-science bestsellers such as Atlas Obscura, Astrophysics for Young People in a Hurry, The Way Things Work, What If?, and Undeniable, the co-founders of the global science organization Nerd Nite bring readers a collection of wacky, yet fascinating STEM topics. For 20 years, Nerd Nite has delivered to live audiences around the world, the most interesting, fun, and informative presentations about science, history, the arts, pop culture, you name it. There hasn't been a rabbit hole that their army of presenters hasn't been afraid to explore. Finally, after countless requests to bring Nerd Nite to more fans across the globe, co-founders and college pals Matt Wasowski and Chris Balakrishnan are bringing readers the quirky and accessible science content that they crave in book form, focused on STEM and paired with detailed illustrations that make the content pop. The resulting range of topics is quirky and vast, from kinky, spring-loaded spiders to the Webb telescope's influence on movie special effects. Hilariously named after Dale Carnegie's iconic book, How to Win Friends and Influence Fungi features narratives, bursts, and infographics on all things STEM from scientists around the world. Chapters are sure to make you laugh-out-loud, with titles such as \"The Science of the Hangover,\" \"What Birds Can Teach Us About the Impending Zombie Apocalypse,\" and \"Lessons from the Oregon Trail.\" With fascinating details, facts, and illustrations, combined with Chris and Matt's incredible connections to organizations such as the Discovery Network and the Smithsonian Institution, How to Win Friends and Influence Fungi is sure to reach joyful STEM enthusiasts of all ages around the world. About Nerd Nite: Started in 2003, Nerd Nite is a monthly event held in 100+ cities worldwide during which folks give 20-minute fun-yet-informative presentations across all disciplines, while the audience drinks along!\"-- Provided by publisher.
The future and why we should avoid it : killer robots, the apocalypse and other topics of mild concern
\"The future holds many unknowns: advances in medical technology, increased airport security and critical new inventions like sentient, polygraph-enabled, wireless toasters. Luckily, Maclean's columnist Scott Feschuk has written a survival guide--part how-to manual, part product guide, part apocalypse analysis and part sardonic observation--to help us navigate these troubled times. Or at least make us laugh while we try. The Future and Why We Should Avoid It envisions the daunting, depressing era we have to look forward to with the best of Feschuk's musings on aging, death, technology, inventions, health and leisure. Combining quizzes, voiceovers and speeches, and employing snark, innuendo, toilet humor and shameless mockery--because how else do you cope with the fact that one day you will die?--Feschuk contemplates the fate of humanity and the planet in the upcoming years, poking fun, provoking thought and dredging up silver linings in even the darkest forecasts\"--From publisher.
Goodnight iPad : a parody for the next generation
In the bright buzzing room, it is time to power down. Here is a modern bedtime story about bidding our gadgets goodnight. Don't worry, though. They'll be waiting for us, fully charged, in the morning.
If you give a mouse an iPhone
From the New York Times-bestselling author of Goodnight iPad comes a new commentary on the perils of our tech-obsessed lives and a fully charged romp for readers of all ages.
Appreciation of different styles of humor: An fMRI study
Humor styles are important in facilitating social relationships. Following humor styles theory, this functional magnetic resonance imaging (fMRI) study is the first to use “one-liner” humor to investigate the neural correlates involved in appreciating humor styles that differ in terms of target (self or other) and motivation (benign or detrimental). Interestingly, we observed greater activation in response to humor that facilitates relationships with others (self-defeating and affiliative humor) than to humor that enhances the self (self-enhancing and aggressive humor). Self-defeating humor may play an important role in Chinese culture in facilitating social relationships at one’s own expense. Psychophysiological interaction (PPI) analysis revealed temporal pole (TP)-frontal functional connectivity underlying the appreciation of self-directed humor, and temporo-parietal junction (TPJ)-frontal connectivity underlying the appreciation of other-directed humor. Amygdala-frontal coupling was observed during the appreciation of detrimental humor, while nucleus accumbens (NAc)-temporal coupling and midbrain-frontal coupling appear to play a role in the affective experience of amusement in response to benign humor. This study contributes to our understanding of the neural correlates of appreciating different humor styles, including humor that facilitates social relationships.
Ultraviolet A light induces DNA damage and estrogen-DNA adducts in Fuchs endothelial corneal dystrophy causing females to be more affected
Fuchs endothelial corneal dystrophy (FECD) is a leading cause of corneal endothelial (CE) degeneration resulting in impaired visual acuity. It is a genetically complex and age-related disorder, with higher incidence in females. In this study, we established a nongenetic FECD animal model based on the physiologic outcome of CE susceptibility to oxidative stress by demonstrating that corneal exposure to ultraviolet A (UVA) recapitulates the morphological and molecular changes of FECD. Targeted irradiation of mouse corneas with UVA induced reactive oxygen species (ROS) production in the aqueous humor, and caused greater CE cell loss, including loss of ZO-1 junctional contacts and corneal edema, in female than male mice, characteristic of late-onset FECD. UVA irradiation caused greater mitochondrial DNA (mtDNA) and nuclear DNA (nDNA) damage in female mice, indicative of the sex-driven differential response of the CE to UVA, thus accounting for more severe phenotype in females. The sex-dependent effect of UVA was driven by the activation of estrogen-metabolizing enzyme CYP1B1 and formation of reactive estrogen metabolites and estrogen-DNA adducts in female but not male mice. Supplementation of N-acetylcysteine (NAC), a scavenger of reactive oxygen species (ROS), diminished the morphological and molecular changes induced by UVA in vivo. This study investigates the molecular mechanisms of environmental factors in FECD pathogenesis and demonstrates a strong link between UVA-induced estrogen metabolism and increased susceptibility of females for FECD development.