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Social distancing is an effective preventative policy for the coronavirus disease (COVID-19) that is enforced by governments worldwide. However, significant variations are observed in following the policy across individuals and countries. Arguably, differences in citizens' adherence actions will be influenced by their perceptions about government's plans and the information available to guide their behaviors-more so in the digital age in the realm of mass influence of social media on citizens. Insights into the underlying factors and dynamics involved with citizens' adherence process will inform the policy makers to follow appropriate communication and messaging approaches to influence citizens' willingness to adhere to the recommendations. The aim of this study is a comparative evaluation of citizens' adherence process to COVID-19-relevant recommendations by the government. The focus is on how three different countries' (United States, Kuwait, and South Korea) citizens, randomly sampled, respond to governments' pandemic guidance efforts. We draw insights into two categories of perceived government roles in managing the pandemic: (1) citizens' perceptions of government's role in responding to the pandemic and (2) citizens' perceptions of government's business reopening efforts. Undoubtedly, the internet and social media have burgeoned, with differing effects on shaping individuals' views and assessments of the COVID-19 situation; we argue and test for the effects of information sources, social media use, and knowledge on the adherence actions. We randomly sampled web-based survey data collected by a global firm in May 2020 from citizens of the United States, Kuwait, and South Korea. A nonlinear ordered probit regression, controlling for several counterfactuals, was used for analysis. The focal estimated effects of the study were compared across countries using the weighted distance between the parameter estimates. The total sample size was 482 respondents, of which 207 (43%) lived in the United States, 181 (38%) lived in Kuwait, and 94 (20%) lived in South Korea. The ordered probit estimation results suggest that overall, perception of government response efforts positively influenced self-adherence (P<.001) and others' adherence (P<.001) to social distancing and sheltering. Perception of government business reopening efforts positively influenced others' adherence (P<.001). A higher intensity of general health information source for COVID-19 had a positive effect on self-adherence (P=.003). A higher intensity of social media source use for COVID-19 positively influenced others' adherence (P=.002). A higher intensity of knowledge on COVID-19 positively influenced self-adherence (P=.008) and negatively influenced others' adherence (P<.001). There were country-level variations-broadly, the United States and Kuwait had better effects than South Korea. As the COVID-19 global pandemic continues to grow and governmental restrictions are ongoing, it is critical to understand people's frustration to reduce panic and promote social distancing to facilitate the control of the pandemic. This study finds that the government plays a central role in terms of adherence to restrictions. Governments need to enhance their efforts on publicizing information on the pandemic, as well as employ strategies for improved communication management to citizens through social media as well as mainstream information sources.

Water reuse is gaining momentum as a beneficial practice to address the water crisis, especially in the agricultural sector as the largest water consumer worldwide. With recent advancements in wastewater treatment technologies, it is possible to produce almost any water quality. However, the main human and environmental concerns are still to determine what constituents must be removed and to what extent. The main objectives of this study were to compile, evaluate, and compare the current agricultural water reuse regulations and guidelines worldwide, and identify the gaps. In total, 70 regulations and guidelines, including Environmental Protection Agency (EPA), International Organization for Standardization (ISO), Food and Agriculture Organization of the United Nations (FAO), World Health Organization (WHO), the United States (state by state), European Commission, Canada (all provinces), Australia, Mexico, Iran, Egypt, Tunisia, Jordan, Palestine, Oman, China, Kuwait, Israel, Saudi Arabia, France, Cyprus, Spain, Greece, Portugal, and Italy were investigated in this study. These regulations and guidelines were examined to compile a comprehensive database, including all of the water quality monitoring parameters, and necessary treatment processes. In summary, results showed that the regulations and guidelines are mainly human-health centered, insufficient regarding some of the potentially dangerous pollutants such as emerging constituents, and with large discrepancies when compared with each other. In addition, some of the important water quality parameters such as some of the pathogens, heavy metals, and salinity are only included in a small group of regulations and guidelines investigated in this study. Finally, specific treatment processes have been only mentioned in some of the regulations and guidelines, and with high levels of discrepancy.

Continuous surveillance is critical for early intervention against emerging novel SARS-CoV-2 variants. Therefore, we investigated and compared the variant-specific evolutionary epidemiology of all the Delta and Omicron sequences collected between 2021 and 2023 in Kuwait. We used Bayesian phylodynamic models to reconstruct, trace, and compare the two variants’ demographics, phylogeographic, and host characteristics in shaping their evolutionary epidemiology. The Omicron had a higher evolutionary rate than the Delta. Both variants underwent periods of sequential growth and decline in their effective population sizes, likely linked to intervention measures and environmental and host characteristics. We found that the Delta strains were frequently introduced into Kuwait from East Asian countries between late 2020 and early 2021, while those of the Omicron strains were most likely from Africa and North America between late 2021 and early 2022. For both variants, our analyses revealed significant transmission routes from patients aged between 20 and 50 years on one side and other age groups, refuting the notion that children are superspreaders for the disease. In contrast, we found that sex has no significant role in the evolutionary history of both variants. We uncovered deeper variant-specific epidemiological insights using phylodynamic models and highlighted the need to integrate such models into current and future genomic surveillance programs.

Sustainable construction is fundamentally different than traditional construction because it requires whole systems thinking, early collaboration across stakeholders, and core principles like reducing resource consumption, eliminating toxins, and applying life cycle costing. Construction professionals unfamiliar with this mindset and approach may perceive sustainable construction as risky. One of the global regions in need of more sustainable construction is the Middle Eastern and North African (MENA) region. The MENA region is one of the fastest developing in the world. However, it is the slowest one in implementing sustainable construction practices. Kuwait, in particular, contributes 53% more carbon emissions per capita than the United States. To understand how the Kuwaiti construction industry perceives risks associated with more sustainable construction, a survey was developed with 52 risk elements in which 131 industry professionals responded. The results indicate that industry professionals perceive a lack of public awareness as the risk element with the highest probability of occurrence. The risk element with the highest possible negative impact on future projects is designers’ and contractors’ inexperience with sustainable construction. Other risks were found to include a high initial cost for materials and overall project costs. Educational interventions, changes in risk allocation, and behavioral science to reframe upfront costs as long-term savings are offered as possible solutions.

Background and Objective of the review There is limited literature on the emergency medicine (EM) specialty in Kuwait, and this paper evaluated the development status of the specialty under Arnold’s classification. Discussion In Kuwait, the EM specialty is recognized with an existing professional society and structured residency training program with post post-board-certification exam. The emergency departments are directed by board-certified emergency physicians with existing emergency medical services and transfer systems. However, there is still a huge demand for trained emergency physicians and a further need to advance the existing trauma system. The academic EM in the country needs further progress in research and developing a specialty journal, databases, and subspecialty training. The management systems within the emergency departments are well developed. Conclusion The EM status is its way to reaching maturity if we overcome a few deficits and challenges in the system. Lastly, two great achievements were made through the establishment of ‘the Kuwait Poison Control Center’ and the simulation training in EM.

Background Prediabetes, a high‐risk state for developing diabetes, has become more prevalent among children and adolescents in recent decades. This study sought to estimate the prevalence of prediabetes and assess its association with adiposity among adolescents in Kuwait. Also, to determine whether maternal and paternal history of diabetes associate with offspring prediabetes in a sex‐specific manner. Methods A cross‐sectional study was conducted by enrolling students (n = 1959; aged 14‐19 years) attending high schools across Kuwait. Body mass index‐for‐age z‐scores were estimated using the World Health Organization growth reference. Glycated hemoglobin A1c (HbA1c) was measured in capillary blood using point‐of‐care testing. Prediabetes was defined according to the diagnostic criteria of the American Diabetes Association (ADA; 5.7 ≤ HbA1c% ≤ 6.4) and the International Expert Committee (IEC; 6.0 ≤ HbA1c% ≤ 6.4). Adjusted prevalence ratios (aPR) and 95% confidence intervals (CI) were estimated using Poisson regression with robust variance estimation. Results According to the ADA criteria, 33.3% (620/1845) of participants had prediabetes; whereas, 8.5% (157/1845) met the IEC definition for prediabetes. Subjects classified as obese had higher prevalence of prediabetes compared to children in the thinness/normal group (aPR = 1.68, 95% CI: 1.44‐1.95). Analysis stratified by offspring sex showed that maternal history of diabetes is associated with prediabetes among male offspring (aPR = 1.29, 95% CI: 1.02‐1.63). In contrast, paternal history of diabetes showed an association with prediabetes among female offspring (aPR = 1.22, 95% CI: 1.01‐1.48). Conclusions Prediabetes affects a substantial proportion of adolescents in Kuwait and adiposity and parental diabetes being the main associated factors with prediabetes.

Cool roofs are roofing systems designed to reflect significant solar radiation, reducing heat absorption and subsequent cooling energy demands in buildings. This paper provides a comprehensive review of cool roof technologies, covering performance standards, material options, energy-saving potential, and hygrothermal considerations. The review examines provisions in current codes and standards, which specify minimum requirements for solar reflectance, thermal emittance, and solar reflectance index (SRI) values. These criteria often vary based on factors like roof slope, climate zone, and building type. Different cool roof materials are explored, including reflective paints and coatings that can be applied to existing roofs as cost-effective solutions. Several studies have demonstrated the energy performance benefits of cool roofs, showing significant reductions in cooling loads, indoor air temperatures, peak cooling demand, and overall cooling energy consumption compared to traditional roofs. However, hygrothermal performance must be evaluated, especially in cold climates, to optimize insulation levels and avoid moisture accumulation risks, as reduced heat absorption can alter moisture migration patterns within the building envelope. While cool roofs provide substantial energy savings in hot climates, further research is needed to validate modeling approaches against real-world studies, investigate the impact of seasonality and green spaces on cool roof efficacy and urban heat island mitigation, and explore energy-saving potential, moisture control, and condensation risks in cold and humid environments.

Alzheimer’s disease (AD), the leading cause of dementia worldwide, remains a challenge due to its complex origin and degenerative character. The need for accurate biomarkers and treatment targets hinders early identification and intervention. To fill this gap, we used a novel longitudinal proteome methodology to examine the temporal development of molecular alterations in the cortex of an intracerebroventricular streptozotocin (ICV-STZ)-induced AD mouse model for disease initiation and progression at one, three-, and six-weeks post-treatment. Week 1 revealed metabolic protein downregulation, such as Aldoa and Pgk1. Week 3 showed increased Synapsin-1, and week 6 showed cytoskeletal protein alterations like Vimentin. The biological pathways, upstream regulators, and functional effects of proteome alterations were dissected using advanced bioinformatics methods, including Ingenuity Pathway Analysis (IPA) and machine learning algorithms. We identified Mitochondrial Dysfunction, Synaptic Vesicle Pathway, and Neuroinflammation Signaling as disease-causing pathways. Huntington’s Disease Signaling and Synaptogenesis Signaling were stimulated while Glutamate Receptor and Calcium Signaling were repressed. IPA also found molecular connections between PPARGC1B and AGT, which are involved in myelination and possible neoplastic processes, and MTOR and AR, which imply mechanistic involvements beyond neurodegeneration. These results help us comprehend AD’s molecular foundation and demonstrate the promise of focused proteomic techniques to uncover new biomarkers and therapeutic targets for AD, enabling personalized medicine.

Climate change in Kuwait has resulted in temperature fluctuations, frequent dust storms, and noticeable changes in the amount of precipitation. Pollutants released into the atmosphere from various sources affect the chemical composition of rainwater and impact its usability. The present study on rainwater focused on the determination of trace elements, sources, and their variation with respect to change in temperature and pH. The samples were collected from 12 different locations in both industrial and urban regions during significant rain events (n = 31) from November 2018 to March 2019 and samples were analyzed for trace elements in ICP-OES using standard USEPA 200.7 method. The mean concentration of the 16 elements analyzed followed the trend: Co < Cd < Cr < Mo < V

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