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result(s) for
"Terence."
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What kind of God? : collected essays of Terence E. Fretheim
by
Fretheim, Terence E.
,
Chan, Michael J.
,
Strawn, Brent A.
in
Bible
,
Bible. Old Testament -- Criticism, interpretation, etc
,
Biblical teaching
2015,2021
Terence E. Fretheim has long been a leading voice in Old Testament theology. In this volume, thirty of his classic studies have been gathered together for the first time under the rubrics \"God and the World\", \"God and Suffering\", \"God, Wrath, and Divine Violence\", \"God and the Pentateuch\", \"God and the Prophets\", and \"God and the Church's Book\". Here readers can find a compelling answer to the question that has motivated Fretheim's work for more than forty years—namely, what kind of God is the God of Scripture? The studies are introduced by a critical overview of Fretheim's career and theology by the editors and a retrospective by Fretheim himself.
Unveiling the mechanisms and challenges of cancer drug resistance
by
Fatima, Kaneez
,
Aisha, Shariqa
,
Khan, Sameer Ullah
in
Antineoplastic Agents - pharmacology
,
Antineoplastic Agents - therapeutic use
,
Apoptosis
2024
Cancer treatment faces many hurdles and resistance is one among them. Anti-cancer treatment strategies are evolving due to innate and acquired resistance capacity, governed by genetic, epigenetic, proteomic, metabolic, or microenvironmental cues that ultimately enable selected cancer cells to survive and progress under unfavorable conditions. Although the mechanism of drug resistance is being widely studied to generate new target-based drugs with better potency than existing ones. However, due to the broader flexibility in acquired drug resistance, advanced therapeutic options with better efficacy need to be explored. Combination therapy is an alternative with a better success rate though the risk of amplified side effects is commonplace. Moreover, recent groundbreaking precision immune therapy is one of the ways to overcome drug resistance and has revolutionized anticancer therapy to a greater extent with the only limitation of being individual-specific and needs further attention. This review will focus on the challenges and strategies opted by cancer cells to withstand the current therapies at the molecular level and also highlights the emerging therapeutic options -like immunological, and stem cell-based options that may prove to have better potential to challenge the existing problem of therapy resistance.
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Video Abstract
Journal Article
Structural Racism and Supporting Black Lives — The Role of Health Professionals
by
Medina, Eduardo M
,
Hardeman, Rachel R
,
Kozhimannil, Katy B
in
African Americans
,
Biomedical Research - standards
,
Castile, Philando
2016
Structural racism leads to increased rates of premature death and reduced levels of overall health and well-being — an epidemic affecting our whole society. As clinicians and researchers, we wield power, privilege, and responsibility for dismantling structural racism.
On July 7, 2016, in our Minneapolis community, Philando Castile was shot and killed by a police officer in the presence of his girlfriend and her 4-year-old daughter. Acknowledging the role of racism in Castile’s death, Minnesota Governor Mark Dayton asked rhetorically, “Would this have happened if those passengers [and] the driver were white? I don’t think it would have.” Such incidents are tragic — and disturbingly common. Indeed, in recent weeks, our country has witnessed the well-publicized deaths of at least three more black men at the hands of police: Terence Crutcher, Keith Scott, and Alfred Olango.
Disproportionate use . . .
Journal Article