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Preterm infants in the neonatal intensive care unit are exposed to various painful procedures; thus, different non-pharmacological pain control techniques are used to alleviate pain. The aim of this study is to determine the effect of Yakson and Gentle Human Touch (GHT) methods during endotracheal suctioning on pain, comfort, and physiological parameters response in preterm infants. A randomised controlled crossover trial. This study was conducted in the neonatal intensive care unit between July 2022 and June 2023. Thirty infants were included in this study based on inclusion criteria. The samples randomly received a sequence of suctioning with Yakson and GHT and routine care. Neonatal Pain Agitation and Sedation Scale (N-PASS) and COMFORTneo were used to collect the data. The pain and comfort scores of preterm infants who received GHT and Yakson touch during and after endotracheal suctioning were statistically significantly lower than the infants in the routine care (p < 0.001). It was determined that the difference was in favour of the Yakson group (p < 0.001). The infants who received GHT and Yakson application had lower heart rates and higher oxygen saturation levels after the application compared to the control group (p < 0.001). The application of Yakson and GHT during endotracheal aspiration in preterm infants has been found to be effective in pain and comfort management, as well as in the regulation of physiological parameters.

As part of preventive health services, infants are exposed to painful procedures, such as venous interventions, injections, and heel blood collection. Infants, in particular, are sensitive and vulnerable to untreated pain. This study aims to evaluate the effect of Yakson touch and white noise on pain in newborn heel blood collection. Yakson touch include the interaction between the caregiver and the care recipient. The study was conducted using a parallel randomized controlled experimental design. The research was conducted during the Guthrie screening test routinely performed on newborns. The study was carried out at the Family Health Center, which has the highest number of patients in a province in the Eastern Anatolia Region of Turkey between May 1st and August 30th, 2022. A total of 66 babies with a gestational age of 37-40 weeks were included in the study. In the study, infant participants were randomly assigned to one of three groups: the Yakson Touch Group (n=22), the White Noise Group (n=22), and the Control Group (n=22). Infants in the Yakson Touch Group received the Yakson touch from the same researcher. Infants in the White Noise Group listened to a song \"Don't Let Your Baby Cry 2\" from the album \"Colic\". Infants in the Control Group received routine intervention procedures. The study data were collected using the Introductory Information Form and the Newborn Infant Pain Scale (NIPS). After the procedure, the mean Yakson Touch Group of the NIPS score was 2.04±1.17, the mean White Noise Group of the NIPS score was 2.80±1.47, and the mean Control Group of the NIPS score was 3.72±1.07. There was a significant difference between the groups after the procedure (P < .001; ηp2=0.248 ). The Yakson touch procedure was found to be the most effective at decreasing the pain score, and white noise was the second most effective. Yakson touch is more effective than white noise in controlling pain due to invasive procedures in babies.

Biofield therapies like Reiki, blessing, and healing touch are non-invasive techniques that aim to enhance well-being-mental, emotional, and physical. They can be conducted both in-person and remotely. However, a literature review found no evidence of distant/remote blessing therapy's effectiveness in improving mental health symptoms in adults. To evaluate the safety and effectiveness of non-pharmacological distant blessing (biofield energy healing) therapy for psychological and mental health management. One hundred seventeen participants with psychological symptoms were studied. On days 0 and 90, the biofield (blessing) therapy group (n = 38) received two sessions of distant blessing energy therapy, each lasting about 5 minutes. A sham control group (n = 40) received similar treatment from a sham practitioner to nullify the baseline responses, while a control group (n = 39) received no intervention. Participants were assessed using a standard psychological questionnaire and safety parameters. A placebo-controlled, three parallel groups, single-center, double-blinded, and randomized controlled trial. Adult human subjects (male and female) with one or more psychological symptoms. Distant (remote) biofield energy healing/blessing therapy. Psychological questionnaires scoring. Perceived psychological symptoms/scores (fatigue/tiredness, sleep disturbances, stress, cognitive impairment, loss of memory, mental restlessness, emotional trauma, anxiety, depression, confusion, lack of relationships, and social behaviors) were significantly improved in the blessing group compared to control and sham control groups (P < .0001). Study intervention did not show any study-related adverse effects in all three groups throughout the trial. The findings from this study suggest that distant (remote) blessing therapy/biofield energy healing session(s) significantly improved psychological and mental health-related symptoms without affecting safety concerns and improved overall health and quality of life. Therefore, the present study recommends a larger-scale intervention study to further investigate various health outcomes and this therapy's underlying mechanisms of action. The trial was registered in the Clinical Trials Registry - India (Reg. no. CTRI/2022/07/043736) dated 05/07/2022.

Background Preterm neonates undergo many painful procedures as part of their standard care in the neonatal intensive care unit. However, pain treatment is inadequate in many of these routine procedures. In the present study, we investigated the impact and mechanism of combined music and touch intervention (CMT) on the pain response in premature infants. Methods Sixty-two preterm neonates (gestational age of <37 weeks) were randomly assigned to either the experimental or control group. Infants in the experimental group underwent painful procedures with CMT, and those in the control group underwent painful procedures without CMT. Blood samples were collected from all infants at the beginning of hospitalization and 2 weeks later to assess the cortisol and β-endorphin concentrations. Differences in the levels of cortisol and β-endorphin between two groups were examined using analysis of covariance (ANCOVA). Results In total, 3707 painful procedures were performed on 62 neonates during their hospitalization. The average number of painful procedures in the control group ( n  = 35.5) was higher than that in the experimental group ( n  = 29.0) during hospitalization, although no significant difference was reached ( P  > 0.05). After 2 weeks, the Premature Infant Pain Profile scores were significantly higher in the control group than experimental group (13.000 ± 0.461 vs 10.500 ± 0.850, respectively; P  < 0.05). The cortisol concentration was not significantly different between the control and experimental groups either at the beginning of hospitalization (131.000 ± 18.190 vs 237.200 ± 43.860, respectively; P  > 0.05) or 2 weeks later (162.400 ± 23.580 vs 184.600 ± 21.170, respectively; P  > 0.05). However, the serum β-endorphin concentration was higher in the experimental group than in the control group both at the beginning of hospitalization (1.640 ± 0.390 vs 1.179 ± 0.090, respectively; P  < 0.05) and 2 weeks later (2.290 ± 0.740 vs 1.390 ± 0.410, respectively; P  < 0.05). Conclusions CMT might decrease the pain response of preterm neonates by significantly improving the β-endorphin concentration, but not the blood cortisol concentration. Trial registration Current Controlled Trials ISRCTN14131492 . Registered on 01 Aug 2016.

Introduction: Cancer treatment with chemotherapy frequently leads to side effects such as fatigue, pain, nausea, and anxiety. Healing Touch is a non-invasive complementary therapy often used by cancer patients to address side effects of treatment. To better inform the use of complementary therapies, there is a need to understand the biological mechanisms underlying the effects of such treatments. Methods: This study included 44 patients with cervical cancer undergoing chemoradiation randomized into a Healing Touch (HT), a relaxation training (RT) and a usual care (UC) group. An exploratory metabolomics analysis was conducted on plasma samples taken at baseline, 4, and 6 weeks of ongoing treatment (4 sessions per week). Results: A multivariate data analysis revealed no significant separation in metabolites between the 3 groups. Univariate data analysis revealed changes in metabolites between baseline and week 6 within each group. The main findings were lower levels of acylcarnitines, bile acids and proline in the HT group, higher levels of fatty acids in the HT and RT groups, and lower levels of kynurenine and quinolate in the UC group. The network of correlations between metabolites shows clear differences in correlations between steroids, fatty acids, sphyngomyelins, amino acids, and γ glutamyl peptides between the 3 groups, suggesting a more flexible and resilient metabolism in the HT and RT groups compared with UC. Conclusion: This first exploratory study investigating metabolic effects of Healing Touch in cancer patients indicated suggestive differences in metabolic signatures which need further investigation in a larger study.

Background Intrauterine insemination (IUI) also found that this experience was associated with anxiety. Therefore, measures must be taken to reduce or eliminate the pain and anxiety associated with it. Objectives This study investigated the effect of virtual reality glasses (VRG) and therapeutic touch (TT) on pain, anxiety and satisfaction during intrauterine insemination. Methods A single blind randomized controlled trial design was used. Patients were randomized into three groups: the virtual reality group (VRG, n  = 32), the therapeutic touch group (TT, n  = 32), and the control group (CG, n  = 32). The study was conducted between January and June 2022 in the obstetric outpatient clinics of a public hospital in northern Türkiye. Anxiety was evaluated using the State Anxiety Inventory. Pain, and satisfaction were evaluated using the Visual Analogue Scale [VAS]. “The study used non-parametric tests for its statistics.” Results There was a significant difference in the pain level of the VRG group during IUI was lower than those of CG 3.7 ± 2.7 and TT 3.6 ± 2.9 ( p  = 0.01). Women were most satisfied with the TT application 9.2 ± 1.1 in the IUI procedure ( p  = 0.000). Anxiety levels after IUI were lower in the TT 43.0 ± 4.2 and VRG 43.9 ± 4.4 than in CG 49.9 ± 4.0 ( p  = 0.000). Conclusion VRG application was effective in reducing pain associated with IUI procedure in women. Although the use of VRG with music reduced the pain associated with IUI more than the TT application, the women left the TT application satisfied. Trial registration The study was registered at the Clinical Trials.gov website under the code NCT05192330. The first trial registration date was (12/01/2022).

I am writing to express concern with the paper \"The impact of Reiki practice on episiotomy recovery and perineal pain: A randomized controlled study.\"1 In this paper, a researcher employed reiki to purportedly bring about beneficial effects. Proponents of reiki claim that in reiki, some form of “universal life energy\" flows from the practitioner to the patient to bring about healing. However, this claim is not recognized by science. Physics knows of no such \"energy,\" nor have proponents been able to demonstrate its existence. Reiki is considered utter pseudoscience by the scientific community.

IntroductionImproving the quality of life for preterm children is a global health priority, given their vulnerability to neurocognitive impairments and adverse health consequences. Lack of posthospital care further exacerbates these risks, necessitating effective interventions during the neonatal period. This protocol for a pilot study aims to investigate the effects of touch interventions, including physiotherapy and osteopathic manipulative treatment, on brain activity in moderately preterm infants using brain functional MRI (fMRI), computerised EEG and metabolomics.Methods and analysisA 3-arm randomised sham-controlled trial will be conducted with 15 infants per experimental group. The study will include stable preterm infants born between 32.0 and 33.6 weeks of gestational age who do not require any intensive care treatments.The study aims to assess the impact of touch interventions on brain activity and metabolic sequelae. Using fMRI will primarily examine the pre-post changes between groups in blood oxygenation level dependent levels among different brain areas, specifically the anterior insula and the medial prefrontal cortex. Secondarily, we will explore the preterm brain’s neural effects on EEG slow delta wave band. Metabolomics will provide data on the effects among the three groups on metabolic changes associated with touch interventions.Ethics and disseminationEthical approval has been obtained from the Ethics Committee of the local health agency in Milan (CET 449-2024). Understanding the effects of touch interventions on brain activity in moderately preterm infants, without needs of intensive care, can contribute to improving their clinical outcomes and promoting their growth, development and social behaviour. Findings from this pilot study will pave the way for future research, enabling the development of evidence-based interventions to enhance preterm infants’ well-being and long-term outcomes.Trial registration numberNCT05853991.

Energy therapies are complementary methods focused on revealing the existing energy and restoring the individual's (recipient's) energy. The aim of this study was to investigate the impact of Reiki practice applied to postpartum women who had spontaneous childbirth without instrumental delivery on postpartum episiotomy recovery and perineal pain. The research was randomized controlled at a hospital in pre-test post-test design. 86 postpartum women in total were included in the research, (n=40) in intervention group and (n=46) in control group. On the postpartum 1st day, 2nd day, 7th day and 14th day, episiotomy recovery of the intervention and control group was assessed with REEDA Scale and perineal pain was assessed with Short Form McGill Pain Questionnaire. The tree sessions of Reiki for 35-40 minutes were applied to intervention group on the postpartum 1st day, 2nd day and 7th day. (Clinical Trial Registry and Registration Number: NCT05486624). The REEDA Scale average oedema scores of the control group postpartum women were higher than intervention group. The control group had higher pain average than the intervention group. The Reiki applied to postpartum women who had spontaneous childbirth without instrumental delivery had a positive impact on episiotomy recovery due to its impact on oedema and it reduced perineal pain. Les thérapies énergétiques sont des méthodes complémentaires axées sur la révélation de l'énergie existante et la restauration de l'énergie de l'individu (du destinataire). Le but de cette étude était d'étudier l'impact de la pratique du Reiki appliquée aux femmes en post-partum ayant eu un accouchement spontané sans accouchement instrumental sur la récupération par épisiotomie postpartum et les douleurs périnéales. La recherche a été randomisée et contrôlée dans un hôpital selon une conception pré-test et posttest. Au total, 86 femmes en post-partum ont été incluses dans la recherche, (n = 40) dans le groupe d'intervention et (n = 46) dans le groupe témoin. Les 1er, 2e, 7e et 14e jours post-partum, la récupération par épisiotomie du groupe d'intervention et du groupe témoin a été évaluée avec l'échelle REEDA et la douleur périnéale a été évaluée avec le questionnaire abrégé sur la douleur de McGill. Les séances d'arbres de Reiki pendant 35 à 40 minutes ont été appliquées au groupe d'intervention les 1er, 2e et 7e jours post-partum. (Registre des essais cliniques et numéro d'enregistrement : NCT05486624). Les scores moyens d'œdème sur l'échelle REEDA des femmes en post-partum du groupe témoin étaient plus élevés que ceux du groupe d'intervention. Le groupe témoin présentait une douleur moyenne plus élevée que le groupe d'intervention. Le Reiki appliqué aux femmes en post-partum ayant eu un accouchement spontané sans accouchement instrumental a eu un impact positif sur la récupération par épisiotomie en raison de son impact sur l'œdème et de la réduction des douleurs périnéales.