Explore the vast range of titles available.

Lung cancer continues to pose a serious global public health challenge. Timely evidence on the global epidemiological profile of the disease is crucial to facilitate the implementation to lung cancer control efforts. This study provides updated global estimates for lung cancer incidence and mortality in 2022, along with projections for new cases and deaths up to 2050. In the population-based study, we extracted data about lung cancer new cases and deaths from GLOBOCAN 2022 database across 185 countries or territories. We analyzed age-standardized rates by sex, country, region, and human development index (HDI). Projected new cases and deaths for 2050 were estimated using global demographic projections. In 2022, lung cancer stood as the most frequently diagnosed cancer and the primary cause of cancer-related deaths on a global scale with approximately 2.48 million new cases and 1.8 million deaths, respectively. The incidence and mortality rates of lung cancer exhibited disparities in sex and world regions. Furthermore, incidence and mortality rates increasing as HDI increased. If the incidence and mortality rates remain stable as in 2022, the burden of lung cancer is projected to increase to 4·62 million new cases and 3·55 million deaths by 2050. Lung cancer is the predominant form of cancer and the foremost contributor to cancer-related mortality in 2022 with notable geographical, sex, and socioeconomic disparities. •Lung cancer is the leading global cause of cancer incidence and mortality, with a strong link to HDI.•Significant sex disparity exists, with higher rates in males.•Urgent, customized strategies are needed to counteract the escalating lung cancer burden and health inequities worldwide.

Background The impact of delayed discharge on patients, health‐care staff and hospital costs has been incompletely characterized. Aim To systematically review experiences of delay from the perspectives of patients, health professionals and hospitals, and its impact on patients’ outcomes and costs. Methods Four of the main biomedical databases were searched for the period 2000‐2016 (February). Quantitative, qualitative and health economic studies conducted in OECD countries were included. Results Thirty‐seven papers reporting data on 35 studies were identified: 10 quantitative, 8 qualitative and 19 exploring costs. Seven of ten quantitative studies were at moderate/low methodological quality; 6 qualitative studies were deemed reliable; and the 19 studies on costs were of moderate quality. Delayed discharge was associated with mortality, infections, depression, reductions in patients’ mobility and their daily activities. The qualitative studies highlighted the pressure to reduce discharge delays on staff stress and interprofessional relationships, with implications for patient care and well‐being. Extra bed‐days could account for up to 30.7% of total costs and cause cancellations of elective operations, treatment delay and repercussions for subsequent services, especially for elderly patients. Conclusions The poor quality of the majority of the research means that implications for practice should be cautiously made. However, the results suggest that the adverse effects of delayed discharge are both direct (through increased opportunities for patients to acquire avoidable ill health) and indirect, secondary to the pressures placed on staff. These findings provide impetus to take a more holistic perspective to addressing delayed discharge.

Background Timely initiation of breastfeeding is defined as putting the newborn to the breast within 1 h of birth. In Ethiopia, different studies have been conducted to assess the prevalence of timely initiation of breastfeeding and associated factors. The findings of these studies were inconsistent and characterized by great variability. Therefore, the aim of this systematic review and meta-analysis was to estimate the pooled prevalence of timely initiation of breastfeeding and its association with birth place in Ethiopia using the available studies. Methods Databases, including PubMed, Google scholar, Science direct and Cochrane library were systematically searched. All original studies reporting the prevalence of timely initiation of breastfeeding in Ethiopia were considered. Two authors independently extracted all necessary data using a standardized data extraction format. STATA 11 statistical software was used to analyze the data. The Cochrane Q test statistics and I 2 test were used to assess the heterogeneity between the studies. A random effect model was computed to estimate the pooled prevalence of timely initiation of breastfeeding. In addition, the associations between timely initiation of breastfeeding and place of birth were determined. Results Sixteen studies were finally included in the meta-analysis. The findings of this meta-analysis revealed that, the pooled prevalence of timely initiation of breastfeeding in Ethiopia was 61.4% (CI: 51.4, 71.5%). The study also indicated that rural mothers had lower rate of initiating breastfeeding within the first 1 h after delivery as compared to their urban counterparts. Additionally, mothers who gave birth at health institution were almost 2.11 times more likely to initiate breastfeeding within 1 h as compared to mothers who did not give birth at health institution. Conclusion In this study, timely initiation of breastfeeding in Ethiopia was significantly low compared to the current global recommendation on breastfeeding. Women from rural area were less likely to initiate breastfeeding within 1 h as compared with women from urban areas. Mothers who give birth at health institution were more likely to initiate breastfeeding timely.

Background Timely access in primary health care is one of the key issues facing health systems. Among many interventions developed around the world, advanced access is the most highly recommended intervention designed specifically to improve timely access in primary care settings. Based on greater accessibility linked with patients’ relational continuity and informational continuity with a primary care professional or team, this organizational model aims to ensure that patients obtain access to healthcare services at a time and date convenient for them when needed regardless of urgency of demand. Its implementation requires a major organizational change based on reorganizing the practices of all the administrative staff and health professionals. In recent years, advanced access has largely been implemented in primary care organizations. However, despite its wide dissemination, we observe considerable variation in the implementation of the five guiding principles of this model across organizations, as well as among professionals working within the same organization. The main objective of this study is to assess the variation in the implementation of the five guiding principles of advanced access in teaching primary healthcare clinics across Quebec and to better understand the influence of the contextual factors on this variation and on outcomes. Methods This study will be based on an explanatory sequential design that includes 1) a quantitative survey conducted in 47 teaching primary healthcare clinics, and 2) a multiple case study using mixed data, contrasted cases (n = 4), representing various implementation profiles and geographical contexts. For each case, semi-structured interviews and focus group will be conducted with professionals and patients. Impact analyses will also be conducted in the four selected clinics using data retrieved from the electronic medical records. Discussion This study is important in social and political context marked by accessibility issues to primary care services. This research is highly relevant in a context of massive media coverage on timely access to primary healthcare and a large-scale implementation of advanced access across Quebec. This study will likely generate useful lessons and support evidence-based practices to refine and adapt the advanced access model to ensure successful implementation in various clinical contexts facing different challenges.

Events that occur after the balance sheet date but before the audit report is signed and dated (subsequent events) may have a material effect on the financial statements and their users. New SEC reporting requirements reduce the time between the balance sheet and report dates, limiting the availability of subsequent event evidence. Professional groups, including the Canadian Institute of Chartered Accountants (CICA) and the American Institute of Certified Public Accountants (AICPA), question whether sufficient evidence will exist if subsequent event information is not available. They fear that decreased availability of subsequent event evidence may lower the quality of both audit judgments and financial reporting. Scant prior research examines auditors' perceptions about subsequent events. Our study examines how auditors search for and discover subsequent event evidence and factors that influence this process. Responses from auditors representing all Big 4 firms and one national firm suggest that subsequent event evidence is important. Auditors generally follow procedures recommended by audit standards; however, recommended procedures uncover subsequent event evidence with low frequency. Implications for future research are discussed.

Purpose - This research seeks to examine whether two relevant characteristics, source objectivity and internal control effectiveness, influence how auditors evaluate evidence items supporting accounting estimates.Design methodology approach - A controlled experiment approach with a sample of 24 auditors from one large international firm.Findings - Results indicate that effective internal controls reduce the impact of relying on internal as opposed to external evidence items. Results also suggest that auditors place reliance on internal control effectiveness when they evaluate external evidence items.Practical implications - Recent professional trends, such as the demand for faster financial reporting, put pressure on auditors to rely on internal rather than more persuasive external evidence items. Relying on less persuasive evidence items reduces audit effectiveness. Auditors may respond by examining a second evidence characteristic; US audit standards suggest evaluating internal control effectiveness if evidence was generated from internal (i.e. client) sources. Thus, this study explores whether internal control effectiveness reduces the impact of relying on evidence items with lower source objectivity.Originality value - Prior research has concentrated on examining the impact of a change in one evidence characteristic on audit judgment; this study expands the understanding of the evidence evaluation process by exploring how auditors evaluate multiple evidence characteristics. Furthermore, as suggested by Bonner, this research identifies an audit judgment deficiency (i.e. reliance on less persuasive internal evidence due to the demand for faster financial reporting) and examines one potential remedy (i.e. consideration of internal control effectiveness).

This chapter contains sections titled: Introduction General forensics Criminalistics Forensic pathology Forensic anthropology Forensic toxicology Odontology Forensic psychiatry and forensic psychology Forensic document examination Digital and multimedia sciences Engineering sciences Jurisprudence International humanitarian applications International forensic systems and forensic research History Training Evidence issues in forensic science Technology Scientific working groups Research Awards Global forensic science References

This chapter contains sections titled: Introduction Instrumentation Applications Conclusion Acknowledgements References