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1,538 result(s) for "Transvestism"
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Trapped in the Wrong Theory: Rethinking Trans Oppression and Resistance
In this essay, I defend an account of trans oppression and resistance that departs from the prevailing transgender model. While I show why both the “trapped in the wrong body” model and the transgender model are problematic, I also illuminate how the former can be seen as a resistant narrative. The new account has two key ideas. First, I draw from María Lugones’s work to defend a model of multiple meanings, arguing that the traditional accounts assume dominant meanings while foreclosing resistant ones. Second, I draw from the recent literature on the transphobic representation of trans people as deceivers to argue that reality enforcement is an important consequence of dominant ways of doing gender. The traditional wrong-body narrative can be seen as resisting reality enforcement.
Sexual Arousal Patterns of Autogynephilic Male Cross-Dressers
Men’s sexual arousal patterns have been an important window into the nature of their erotic interests. Autogynephilia is a natal male’s paraphilic tendency to be sexually aroused by the thought or image of being a woman. Autogynephilic arousal per se is difficult to assess objectively, because it is inwardly focused. However, assessing sexual arousal patterns of autogynephilic males in response to external stimuli is also potentially useful. For example, there is substantial association between autogynephilia and gynandromorphophilia (GAMP), or sexual attraction to gynandromorphs (GAMs), colloquially “she-males.” GAMP men’s sexual arousal patterns in response to GAM, female, and male stimuli have recently been characterized. In the present study, we extended this understanding by comparing the sexual arousal patterns of autogynephilic male cross-dressers, GAMP men, heterosexual men, and homosexual men. Erotic stimuli included sexually explicit videos of men, women, and GAMs. Autogynephilic men were much more similar in their arousal patterns to heterosexual and GAMP men than to homosexual men. However, similar to GAMP men, autogynephilic men showed increased arousal by GAM stimuli relative to female stimuli compared with heterosexual men.
Cross-dressed dendritic cells sustain effector T cell responses in islet and kidney allografts
Activation of host T cells that mediate allograft rejection is a 2-step process. The first occurs in secondary lymphoid organs where T cells encounter alloantigens presented by host DCs and differentiate to effectors. Antigen presentation at these sites occurs principally via transfer of intact, donor MHC-peptide complexes from graft cells to host DCs (cross-dressing) or by uptake and processing of donor antigens into allopeptides bound to self-MHC molecules (indirect presentation). The second step takes place in the graft, where effector T cells reengage with host DCs before causing rejection. How host DCs present alloantigens to T cells in the graft is not known. Using mouse islet and kidney transplantation models, imaging cytometry, and 2-photon intravital microscopy, we demonstrate extensive cross-dressing of intragraft host DCs with donor MHC-peptide complexes that occurred early after transplantation, whereas host DCs presenting donor antigen via the indirect pathway were rare. Cross-dressed DCs stably engaged TCR-transgenic effector CD8+ T cells that recognized donor antigen and were sufficient for sustaining acute rejection. In the chronic kidney rejection model, cross-dressing declined over time but was still conspicuous 8 weeks after transplantation. We conclude that cross-dressing of host DCs with donor MHC molecules is a major antigen presentation pathway driving effector T cell responses within allografts.
Police violence and sexual risk among female and transvestite sex workers in Serbia: qualitative study
Objective To explore female and transvestite sex workers’ perceptions of risk in the sex work environment in Serbia.Design Qualitative interview study.Setting Street based locations for sex work in Belgrade and Pancevo, Serbia.Participants 31 female and transvestite sex workers.Results Violence, including police violence, was reported as a primary concern in relation to risk. Violence was linked to unprotected sex and the reduced capacity for avoiding sexual risk. Participants reported that coerced sex was routinely provided to the police in exchange for freedom from detainment, arrest, or fine, and was enforced by the perceived threat of violence, sometimes realised. Accounts contained multiple instances of physical and sexual assault, presented as abuses of police authority, and described policing as a form of moral punishment. This was largely through non-physical means but was also enforced through physical violence, especially towards transvestite and Roma sex workers, whose experience of police violence was reported as relentless and brutal and connected with broader social forces of discrimination in this setting, especially towards Roma.Conclusion Preventing violence towards sex workers, which can link with vulnerability to sexually transmitted infections, is a priority in Serbia. This requires monitoring perpetrators of violence, providing legal support to sex workers, and creating safer environments for sex work.
CD47 cross-dressing by extracellular vesicles expressing CD47 inhibits phagocytosis without transmitting cell death signals
Transgenic CD47 overexpression is an encouraging approach to ameliorating xenograft rejection and alloresponses to pluripotent stem cells, and the efficacy correlates with the level of CD47 expression. However, CD47, upon ligation, also transmits signals leading to cell dysfunction or death, raising a concern that overexpressing CD47 could be harmful. Here, we unveiled an alternative source of cell surface CD47. We showed that extracellular vesicles, including exosomes, released from normal or tumor cells overexpressing CD47 (transgenic or native) can induce efficient CD47 cross-dressing on pig or human cells. Like the autogenous CD47, CD47 cross-dressed on cell surfaces is capable of interacting with SIRPα to inhibit phagocytosis. However, ligation of the autogenous, but not cross-dressed, CD47 induced cell death. Thus, CD47 cross-dressing provides an alternative source of cell surface CD47 that may elicit its anti-phagocytic function without transmitting harmful signals to the cells. CD47 cross-dressing also suggests a previously unidentified mechanism for tumor-induced immunosuppression. Our findings should help to further optimize the CD47 transgenic approach that may improve outcomes by minimizing the harmful effects of CD47 overexpression.
Queer Embodiment
Merging critical theory, autobiography, and sexological archival research, Queer Embodiment provides insight into what it means, and has meant, to have a legible body in the West. Hilary Malatino explores how and why intersexuality became an anomalous embodiment requiring correction and how contesting this pathologization can promote medical reform and human rights for intersex and trans persons. Malatino traces both institutional and interpersonal failures to dignify non-sexually dimorphic bodies and examines the ways in which the ontology of gender difference developed by modern sexologists conflicts with embodied experience. Malatino comprehensively shows how gender-normalizing practices begin at the clinic but are then amplified over time at both intimate and systemic levels, through mechanisms of institutional exclusion and through contemporary Eurocentric cultures' cis-centric and bio-normative understanding of sexuality, reproductive capacity, romantic partnership, and kinship. Combining personal accounts with archival evidence, Malatino presents intersexuality as the conceptual shibboleth of queerness, the figure through which nonnormative genders and desires are, and have been historically, understood. The medical, scientific, and philosophical discourse on intersexuality underlying our contemporary understanding of sexed selfhood requires theoretical and ethical reconsideration in order to facilitate understanding gender anew as an intra-active and continually differentiating process of becoming that exceeds and undoes restrictive binary logic.
Perceived Risks and Benefits of Sex Work among Transgender Women of Color in San Francisco
Prior research has shown that male-to-female (MTF) transgender women of color in the United States have a high rate of HIV infection and often engage in sex work for economic survival. With the exception of studies on HIV prevalence and behavioral risk, little research exists to elucidate the social context and determinants of sex work and related health risks among these women. Through a qualitative analysis of seven focus groups with 48 transgender women of color, we examined why and how participants became involved in sex work, documented risks associated with sex work, and explored what motivated participants to remain in sex work. Participants reported on how social networks and cultural norms, immigration issues, and experiences of racism, sexism, and transphobia influenced their decisions to enter and the risks encountered in sex work. Findings revealed that transgender women of color who engage in sex work have unique needs and experiences that must be addressed through structural and social network-based interventions to minimize their vulnerability to social and public health harms.
Boyish Mannerisms and Womanly Coquetry: Patients with the Diagnosis of Transvestitismus in the Helsinki Psychiatric Clinic in Finland, 1954–68
This article examines the case files of patients diagnosed with Transvestitismus [transvestism] in the Psychiatric Clinic of the Helsinki University Central Hospital in the years 1954–68. These individuals did not only want to cross-dress, but also had a strong feeling of being of a different sex from their assigned one. The scientific concept of transsexuality had begun to take form, and this knowledge reached Finland in phases. The case files of the transvestism patients show that they were highly aware of their condition and were very capable of describing it, even if they had no medical name for it. Psychiatrists were willing to engage in dialogue with the patients, and did not treat them as passive objects of study. Although some patients felt that they had been helped, many left the institution as frustrated, angered or desperate as before. They had sought medical help in the hope of having their bodies altered to correspond to their identity, but the Clinic psychiatrists insisted on seeing the problem in psychiatric terms and did not recommend surgical or hormonal treatments in most cases. This attitude would gradually change over the course of the 1970s and 1980s.