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Damage detection of railway tracks is vital to ensure normal operation and safety of the rail transit system. Piezoelectric sensors, which are widely utilized to receive ultrasonic wave, may be disturbed in the railway system due to strong electromagnetic interference (EMI). In this work, a hybrid ultrasonic sensing system is proposed and validated by utilizing a lead-zirconate-titanate (PZT) actuator and a fiber Bragg grating (FBG) sensor to evaluate damage conditions of the railway tracks. The conventional ultrasonic guided wave-based method utilizing direct wave to detect damages is limited by the complex data analysis procedure and low sensitivity to incipient damage. Diffuse ultrasonic wave (DUW), referring to later arrival wave packets, is chosen in this study to evaluate structural conditions of railway tracks due to its high sensitivity, wider sensing range, and easy implementation. Damages with different sizes and locations are introduced on the railway track to validate the sensitivity and sensing range of the proposed method. Two damage indices are defined from the perspective of energy attenuation and waveform distortion. The experimental results demonstrate that the DUW signals received by the hybrid sensing system could be used for damage detection of the railway tracks and the waveform-distortion-based index is more efficient than the energy-based index.

Objective. Studies regarding the combination of ultrasound and transcutaneous electrical nerve stimulation (TENS) are rarely reported. In this study, we aimed to elucidate the efficacy and safety of a stimulator using low-intensity pulsed ultrasound (LIPUS) combined with TENS in patients with painful knee osteoarthritis (OA). We evaluated the effectiveness of this therapy against pain, physical function, and cartilage regeneration. Moreover, we aim to prove the superiority of the effects of LIPUS combined with TENS therapy compared with only TENS therapy. Methods. Of the 40 included patients, aged 45–85 years with painful knee OA, 20 patients received only TENS therapy and 20 patients received LIPUS combined with TENS therapy for 8 weeks (a total of more than 80 treatment sessions). We evaluated visual analogue scale (VAS), Western Ontario and McMaster Universities (WOMAC) osteoarthritis index, MOS 36-Item Short-Form Health Survey (SF-36), and femoral articular cartilage (FAC) thickness. The evaluation was performed at three visits: visit 1 (V1, pretreatment, within 28 days after screening), visit 2 (V2, posttreatment period 1, ±3 days after treatment), and visit 3 (V3, posttreatment period 2, 21 ± 3 days after treatment). Results. We expected that LIPUS combined with TENS therapy would be superior to only TENS therapy. However, there was no significant difference between the two therapies. In the within-group comparison, both treatments (only TENS therapy and LIPUS with TENS therapy) demonstrated statistical differences from baseline values for pain and physical function outcomes. FAC thickness showed no significant differences after treatment in both groups. Conclusion. The effects of a stimulator using LIPUS with TENS on pain relief and functional improvement were not superior to the only TENS therapy. Cartilage regeneration, which was expected as an additional benefit of LIPUS, was also not significantly evident. Therefore, further investigation is warranted to determine whether the combination therapy is beneficial. This trial is registered with KCT0003883.

Ultrasonic guided wave (UGW) is one of the most commonly used technologies for non-destructive evaluation (NDE) and structural health monitoring (SHM) of structural components. Because of its excellent long-range diagnostic capability, this method is effective in detecting cracks, material loss, and fatigue-based defects in isotropic and anisotropic structures. The shape and orientation of structural defects are critical parameters during the investigation of crack propagation, assessment of damage severity, and prediction of remaining useful life (RUL) of structures. These parameters become even more important in cases where the crack intensity is associated with the safety of men, environment, and material, such as ship’s hull, aero-structures, rail tracks and subsea pipelines. This paper reviews the research literature on UGWs and their application in defect diagnosis and health monitoring of metallic structures. It has been observed that no significant research work has been convened to identify the shape and orientation of defects in plate-like structures. We also propose an experimental research work assisted by numerical simulations to investigate the response of UGWs upon interaction with cracks in different shapes and orientations. A framework for an empirical model may be considered to determine these structural flaws.

Unidirectional ultrasonic guided waves (UGWs) play a crucial role in the nondestructive testing and evaluation (NDT&E) domains, offering unique advantages in detecting material defects, evaluating structural integrity, and improving the accuracy of thickness measurements. This review paper thoroughly studies the state of the art of unidirectional UGWs before presenting a comprehensive review of the foundational mathematical principles of unidirectional UGWs, focusing on the recent advancements in their methodologies and applications. This review introduces ultrasonic guided waves and their modes before looking at mode excitability and selectivity, signal excitation, and mechanisms used to generate and receive guided waves unidirectionally. This paper outlines the applications of unidirectional UGWs to reflect their effectiveness, for instance, in measuring thickness and in identifying defects such as cracks and corrosion in pipelines, etc. The paper also studies the challenges associated with unidirectional UGW generation and utilisation, such as multi-mode and side lobes. It includes a review of the literature to mitigate these challenges. Finally, this paper highlights promising future perspectives and develops directions for the technique. This review aims to create a useful resource for researchers and practitioners to comprehend unidirectional ultrasonic guided waves’ capabilities, challenges, and prospects in NDT&E applications.

Piezoelectric ultrasonic motors (USMs) are actuators that use ultrasonic frequency piezoelectric vibration-generated waves to transform electrical energy into rotary or translating motion. USMs receive more attention because they offer distinct qualities over traditional magnet-coil-based motors, such as miniaturization, great accuracy, speed, non-magnetic nature, silent operation, straightforward construction, broad temperature operations, and adaptability. This review study focuses on the principle of USMs and their classifications, characterization, fabrication methods, applications, and future challenges. Firstly, the classifications of USMs, especially, standing-wave, traveling-wave, hybrid-mode, and multi-degree-of-freedom USMs, are summarized, and their respective functioning principles are explained. Secondly, finite element modeling analysis for design and performance predictions, conventional and nano/micro-fabrication methods, and various characterization methods are presented. Thirdly, their advantages, such as high accuracy, small size, and silent operation, and their benefits over conventional motors for the different specific applications are examined. Fourthly, the advantages and disadvantages of USMs are highlighted. In addition, their substantial contributions to a variety of technical fields like surgical robots and industrial, aerospace, and biomedical applications are introduced. Finally, their future prospects and challenges, as well as research directions in USM development, are outlined, with an emphasis on downsizing, increasing efficiency, and new materials.

The water–cement ratio significantly affects the mechanical properties of concrete with changes in porosity serving as a key indicator of these properties, which are correlated with the ultrasonic wave velocity and energy evolution. This study conducts uniaxial compression tests on concrete with varying water–cement ratios, analyzing energy evolution and ultrasonic wave velocity variations during the pore compaction stage and comparing damage variables defined by dissipated energy and ultrasonic wave velocity. The results indicate the following findings. (1) Higher water–cement ratios lead to more complete hydration, lower initial porosity, and a less pronounced pore compaction stage, but they deteriorate mechanical properties. (2) In the pore compaction stage, damage variables defined by dissipated energy are more regular than those defined by ultrasonic wave velocity, showing a nearly linear increase with stress (D = 0~0.025); ultrasonic wave variables fluctuate within −0.06 to 0.04 due to diffraction caused by changes in the pore medium. (3) In the pre-peak stress stage, damage variables defined by ultrasonic wave velocity show a distinct threshold. When the stress ratio exceeds about 0.3, the damage variable curve’s growth shows clear regularity, significantly reflecting porosity changes. In conclusion, for studying porosity changes during the pore compaction stage, damage variables defined by dissipated energy are more effective.

Introduction Ultrasound waves can affect bone and bone marrow, and widespread medical and industrial use increases the likelihood of direct or indirect exposure. This systematic review summarizes current evidence on the biological and biomechanical effects of high- and low-intensity ultrasound on skeletal tissues, with emphasis on safety. Methods A systematic search was conducted across PubMed, ScienceDirect, Wiley Online Library, EMBASE, JSTOR, IEEE Xplore, Scopus, and Google Scholar (up to October 2024), guided by a PICO-based strategy. Studies were screened using predefined eligibility criteria, and 29 articles met the inclusion criteria for synthesis. Study quality was appraised using the Newcastle–Ottawa Scale (NOS) and the 2018 Mixed Methods Appraisal Tool (MMAT). The protocol was registered in PROSPERO (CRD42024620731). Results Ultrasound technology has significant implications for health and safety due to its medical and industrial applications. High-intensity ultrasound waves may cause tissue damage, reduce bone density, and even lead to necrosis. However, controlled low-intensity ultrasound can be beneficial in medical treatments and tissue healing. Conclusions To minimize potential risks, it is crucial to establish safety standards and enhance public awareness regarding the appropriate use of ultrasound technology. In summary, while prolonged exposure to ultrasound may adversely affect bone density and marrow integrity, the technology retains significant value in diagnostic and therapeutic applications.

Sonodynamic therapy (SDT) is a promising non-invasive adjuvant approach for treating accessible tumors, requiring ultrasound (US) waves, sonosensitizing molecules, and oxygen. However, sonosensitizers such as protoporphyrin IX (PpIX) face limitations, including poor water solubility, phototoxicity, and lack of targeting. To address these issues, we encapsulated PpIX in biocompatible nanomicelles to enhance solubility, reduce side effects, and improve tumor targeting. After synthesizing, characterizing, and assessing the cytotoxicity of PpIX-loaded nanomicelles, the optimal concentration was selected. The 4T1 cell line was used to create a breast tumor model in BALB/c mice. To investigate the effect of SDT mediated by PpIX-loaded nanomicelles, tumors were exposed to US at 800 and 2400 kHz simultaneously, 10 min after intratumoral injection of the drug. The tumors were measured with a digital calliper, and tumor volume was calculated at specific time intervals and compared. The tumor tissue necrosis percentage was determined by pathological examination, and the volume loss in different groups was quantified. SDT with PpIX nanomicelles significantly reduced tumor volume within 7 days compared with controls ( <0.05), with the greatest volume loss observed in this group. Pathological analysis confirmed extensive tumor necrosis. PpIX-loaded nanomicelles enhance SDT efficacy in breast tumors, demonstrating potential as a targeted delivery system. Repeated treatments may further inhibit tumor growth.

One of the methods used to discover the development of deterioration in bricks used as a construction material in a building is the monitoring of the bricks’ strength characteristics over time. However, measuring the strength characteristics of bricks used in a building requires sampling for performing laboratory tests, which is not possible in some cases. As an alternative, ultrasonic wave velocity can be a useful, nondestructive tool for the indirect assessment of the strength characteristics of the bricks. In the present study, six different samples of clay bricks before utilization as construction materials in buildings located in Khorramabad City (Lorestan Province, western Iran) were collected. The mineralogical composition of the samples was studied using X-ray diffraction (XRD) analysis. As one common physical characteristic of the construction materials, the porosity (n) of the samples was measured. Next, the strength characteristics, including uniaxial compressive strength (UCS), Brazilian tensile strength (BTS), and P-wave velocity (Vp), of the samples under dry and saturated conditions were determined. It was found that after the saturation of the samples, considerable decreases in the UCS and BTS and increases in the Vp occurred, respectively. By comparing the values of the UCS, BTS, and Vp of the samples under dry and saturated conditions, we found that the integrity loss for the UCS and BTS was higher than for the Vp. Results showed that the integrity loss of the UCS, BTS, and Vp was significantly affected by the n and clay mineral (CM) content of the samples. Considering the dry or saturated condition of the samples, there are good correlations with acceptable accuracy levels between the Vp and the UCS and BTS, with coefficients of determination (R2) varying from 0.95 to 0.98. Consequently, our findings showed that establishing UCS and BTS predictive equations for bricks before their use as a construction material can be a worthy, practical tool for monitoring the deterioration of bricks over time after their utilization in a building.

Ultrasound-(US) emitting sources are highly present in modern human environments (e.g., movement sensors, electric transformers). US affecting humans or even posing a health hazard remains understudied. Hence, ultrasonic (22.4 kHz) vs. sham devices were installed in participants’ bedrooms, and active for 28 nights. Somatic and psychiatric symptoms, sound-sensitivity, sleep quality, executive function, and structural MRI were assessed pre-post. Somatization (possible nocebo) and phasic alertness increased significantly in sham, accuracy in a flexibility task decreased significantly in the verum condition (indicating hastier responses). Effects were not sustained after p -level adjustment. Exploratory voxel-based morphometry (VBM) revealed regional grey matter (rGMV) but no regional white matter volume changes in verum (relative to placebo). rGMV increased in bilateral cerebellum VIIb/Crus II and anterior cingulate (BA24). There were rGMV decreases in two bilateral frontal clusters: in the middle frontal gyri/opercular part of inferior frontal gyrus (BA46, 44), and the superior frontal gyri (BA4 ,6, 8). No brain-behavior-links were identified. Given the overall pattern of results, it is suggested that ultrasound may particularly induce regional gray matter decline in frontal areas, however with yet unclear behavioral consequences. Given the localization of clusters, candidate behavioral variables for follow-up investigation are complex motor control/coordination, stress regulation, speech processing, and inhibition tasks. Trial registration : The trial was registered at NIH www.clinicaltrials.gov , trial identifier: NCT03459183, trial name: SonicBrain01, full trial protocol available here: https://clinicaltrials.gov/ct2/show/NCT03459183 .