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"Women in medicine Juvenile literature."
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Bold women of medicine : 21 stories of astounding discoveries, daring surgeries, and healing breakthroughs
Meet determined women who have dedicated their lives to saving others! From bold pioneers such as Florence Nightingale and Mary Edwards Walker, to modern-day medical heroines, readers will meet women who inspire with t heir courage and persistence.
Book
A randomized controlled efficacy trial of an electronic screening and brief intervention for alcohol misuse in adolescents and young adults vulnerable to HIV infection: step up, test up study protocol
Background
Young people account for more than a quarter of new HIV infections in the US, with the majority of cases among young men who have sex with men; young transgender women are also vulnerable to infection. Substance use, particularly alcohol misuse, is a driver of sexual transmission and a potential barrier to engagement in the HIV prevention and care continuum, however vulnerable youth are difficult to reach for substance use services due, in part, to complex social and structural factors and limited access to health care. The Community Prevention Services Task Force recommends electronic screening and brief intervention as an evidence-based intervention for the prevention of excessive alcohol consumption; however, no prior studies have extended this model to community-based populations of youth that are susceptible to HIV infection. This paper describes the study protocol for an electronic screening and brief intervention to reduce alcohol misuse among adolescents and young adults vulnerable to HIV infection in community-based settings.
Methods
This study, Step Up, Test Up, is a randomized controlled trial of an electronic alcohol screening and brief intervention among youth, ages 16–25, who are vulnerable to HIV infection. Individuals who present for HIV testing at one of three community-based locations are recruited for study participation. Eligibility includes those aged 16–25 years, HIV-negative or unknown HIV status, male or trans female with a history of sex with men, and English-speaking. Participants who screen at moderate to high risk for alcohol misuse on the Alcohol Use Disorders Identification Test (AUDIT) are randomized (1:1) to either an electronic brief intervention to reduce alcohol misuse or a time-and attention-matched control. The primary outcome is change in the frequency/quantity of recent alcohol use at 1, 3, 6 and 12-month follow-up.
Discussion
Testing of evidence-based interventions to reduce alcohol misuse among youth vulnerable to HIV infection are needed. This study will provide evidence to determine feasibility and efficacy of a brief electronically-delivered intervention to reduce alcohol misuse for this population.
Trial registration
ClinicalTrials.gov number,
NCT02703116
, registered March 9, 2016.
Journal Article
Magnificent minds : sixteen pioneering women of science and medicine
\"...introduces the lives, sayings, and dreams of sixteen women over four centuries and chronicles their contributions to mathematics, physics, chemistry, astronomy, computer science, and medicine.\"--Amazon.com.
Book
Remission of HPV-Related Diseases by Antivirals for Herpesvirus: Clinical Cases and a Literature Review
Epidemiological studies have shown that HPV-related diseases are the most prevalent sexually transmitted infections. In this context, this report will present various clinical cases demonstrating the effectiveness of Acyclovir (ACV) or its prodrug Valaciclovir (VCV), both acyclic guanosine analogs commonly used for the treatment of HHV-1 and HHV-2, for the treatment of HPV-related diseases. The report shows the remission of five cases of penile condyloma and a case of remission in a woman affected by cervical and vaginal condylomas and a vulvar giant condyloma acuminate of Buschke and Lowenstein. The literature review shows that ACV is effective in treating skin warts when administered orally, topically, and intralesionally, suggesting its therapeutic potential in other diseases associated with HPV. ACV was also used successfully as an adjuvant therapy for juvenile and adult forms of laryngeal papillomatosis, also known as recurrent respiratory papillomatosis, prolonging the patient’s symptom-free periods. Although the prevention of HPV infections is certainly achieved with the HPV vaccine, ACV and VCV have shown to be effective even against genotypes not included in the current vaccine and can be helpful for those problematic clinical cases involving unvaccinated individuals, immunocompromised patients, people who live with HIV, or non-responders to the vaccine. We and others concluded that randomized clinical trials are necessary to determine the efficacy of ACV and VCV for HPV-related diseases.
Journal Article
Ovarian Gynandroblastoma with a Juvenile Granulosa Cell Tumor Component in a Postmenopausal Woman
Ovarian gynandroblastoma (GAB) is an extremely rare sex cord-stromal tumor showing morphological evidence of both female (granulosa cell tumor) and male (Sertoli–Leydig cell tumor (SLCT)) components. Almost all GAB cases have been reported in children, adolescents, or women of reproductive age, and most of them typically have adult granulosa cell tumors as the female component. In contrast, GAB with a juvenile granulosa cell tumor (JGCT) component is a very rare condition; to the best of our knowledge, only one case of GAB with JGCT in a postmenopausal woman has been reported. In this report, we present an extremely rare case of ovarian GAB with JGCT in an elderly patient. A 65-year-old woman presented with an abdominal mass. Abdominopelvic magnetic resonance imaging revealed a large multiseptated cystic mass measuring 20 cm. No peritoneal seeding, lymph node enlargement, or hematogenous metastasis was identified. Laboratory test showed a slight elevation of serum CA 125 level (37.1 U/mL). Based on the preoperative clinical impression of ovarian cancer, she underwent a total hysterectomy with bilateral salpingo-oophorectomy. Grossly, the ovarian mass had a smooth and glistening surface without excrescences. The cut sections showed yellow-to-tan solid areas with foci of necrosis, myxoid degeneration, and hemorrhage, as well as multilocular cystic cavities filled with serosanguinous fluid. Histologically, the female component was characterized by JGCT displaying nodular growth patterns with follicle-like structures of various shapes and sizes. Most of the microcysts contained eosinophilic or basophilic secretions. The JGCT cells had indistinct cell borders, an abundant eosinophilic cytoplasm, and round-to-oval hyperchromatic nuclei with many mitotic figures. The SLCT component consisted predominantly of intermediately differentiated Sertoli cells forming lobulated solid nodules. They were arranged in cords, solid tubules, or nests, and possessed oval-to-spindle-shaped darkly stained nuclei and scant cytoplasm. In several foci, well-formed Sertoli cell tubules were loosely aggregated within areas of moderately differentiated SLCT. In summary, we described GAB in a postmenopausal woman with JGCT and SLCT as the female and male components, respectively. This is the second case of GAB with JGCT occurring in an elderly patient. Our findings can help pathologists and clinicians make accurate histological diagnoses of GAB with a JGCT component and plan an adequate treatment strategy for this rare tumor.
Journal Article
Barriers to abortion facing Mexican immigrants in North Carolina: Choosing folk healers versus standard medical options
Abortion is among the most stigmatized reproductive health issues faced by women in the United States. Using the reproductive justice framework, we discuss the numerous obstacles Mexican immigrant women and teens living in North Carolina face in seeking abortions and the ways in which the barriers experienced by these women are the product of intersecting forms of oppression based on race, gender, sexuality, class, ability, age, immigration status and linguistic abilities, among others. These struggles are depicted through ethnographic data as well as interviews with midwives, program directors, folk healers (
curanderas/os
) and Mexican immigrant women and girls making decisions about abortion. Their experiences are analyzed to highlight that Mexican immigrant women and teens are restricted by legal and medical institutions. The findings focus on how these women ultimately receive abortion services in the face of structural barriers to formal care and why women often seek abortion care outside of the formal health-care sector.
Journal Article
The Atlanta Journal-Constitution, Life with Gracie column
Not only do we still get to enjoy the emotional support of parents and other family members, we can count on their financial backing as well and well past the age of 18. In addition to providing supportive services for children in foster care, including recreation, mentoringand a residential group home, the foundation hosts a weeklong residential camp and partners with the Atlanta Hawks to provide a basketball mentoring program.
Newsletter
Ventura County Star, Calif., Business Briefs Column
JUSTCHEX LLC SIGNS DOMINO'S PARTNERSHIP: OXNARD, Calif.-- Justchex LLC, a provider of online returned check recovery services, has signed an affinity partnership agreement with the Domino's Franchisee Association, an organization of Domino's Pizza restaurant owners, Oxnard based Justchex announced. Domino's franchise owners were among Justchex's earliest customers, said Richard McShirley, director of business development for Justchex. With Justchex automated processing of returned checks, clients recover an increased percentage of the face value of bad checks. Justchex makes money by deducting its fee from the state-allowed returned check fee that can be collected from the check writer.
Newsletter