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To understand a city fully, writes Di Wang, we must observe its most basic units of social life. InThe Teahouse under Socialism, Wang does just that, arguing that the teahouses of Chengdu, the capital of Sichuan Province, are some of the most important public spaces-perfect sites for examining the social and economic activities of everyday Chinese. Wang looks at the transformation of these teahouses from private businesses to collective ownership and how state policy and the proprietors' response to it changed the overall economic and social structure of the city. He uses this transformation to illuminate broader trends in China's urban public life from 1950 through the end of the Cultural Revolution and into the post-Mao reform era. In doing so,The Teahouse under Socialismcharts the fluctuations in fortune of this ancient cultural institution and analyzes how it survived, and even thrived, under bleak conditions. Throughout, Wang asks such questions as: Why and how did state power intervene in the operation of small businesses? How was \"socialist entertainment\" established in a local society? How did the well-known waves of political contestation and struggle in China change Chengdu's teahouses and public life? In the end, Wang argues, the answers to such questions enhance our understanding of public life and political culture in the Communist state.

\"An elite police squad hunts a manipulative mastermind out to publically execute criminals the law cannot reach\"-- Provided by publisher.

Who exactly are China's new rich? This pioneering investigation introduces readers to the private lives—and the nightlives—of the powerful entrepreneurs and managers redefining success and status in the city of Chengdu. Over the course of more than three years, anthropologist John Osburg accompanied, and in some instances assisted, wealthy Chinese businessmen as they courted clients, partners, and government officials. Drawing on his immersive experiences, Osburg invites readers to join him as he journeys through the new, highly gendered entertainment sites for Chinese businessmen, including karaoke clubs, saunas, and massage parlors—places specifically designed to cater to the desires and enjoyment of elite men. Within these spaces, a masculinization of business is taking place. Osburg details the complex code of behavior that governs businessmen as they go about banqueting, drinking, gambling, bribing, exchanging gifts, and obtaining sexual services. These intricate social networks play a key role in generating business, performing social status, and reconfiguring gender roles. But many entrepreneurs feel trapped by their obligations and moral compromises in this evolving environment. Ultimately, Osburg examines their deep ambivalence about China's future and their own complicity in the major issues of post-Mao Chinese society—corruption, inequality, materialism, and loss of trust.

Photothermal therapy (PTT) has great potential in the clinical treatment of tumors. However, most photothermal materials are difficult to apply due to their insufficient photothermal conversion efficiencies (PCEs), poor photostabilities and short circulation times. Furthermore, tumor recurrence is likely to occur using PTT only. In the present study, we prepared cyclo (Arg-Gly-Asp-d-Phe-Cys) [c(RGD)] conjugated doxorubicin (DOX)-loaded Fe3O4@polydopamine (PDA) nanoparticles to develop a multifunctional-targeted nanocomplex for integrated tumor diagnosis and treatment.BACKGROUNDPhotothermal therapy (PTT) has great potential in the clinical treatment of tumors. However, most photothermal materials are difficult to apply due to their insufficient photothermal conversion efficiencies (PCEs), poor photostabilities and short circulation times. Furthermore, tumor recurrence is likely to occur using PTT only. In the present study, we prepared cyclo (Arg-Gly-Asp-d-Phe-Cys) [c(RGD)] conjugated doxorubicin (DOX)-loaded Fe3O4@polydopamine (PDA) nanoparticles to develop a multifunctional-targeted nanocomplex for integrated tumor diagnosis and treatment.Cytotoxicity of Fe3O4@PDA-PEG-cRGD-DOX against HCT-116 cells was determined by cck-8 assay. Cellular uptake was measured by confocal laser scanning microscope (CLSM). Pharmacokinetic performance of DOX was evaluated to compare the differences between free DOX and DOX in nanocarrier. Performance in magnetic resonance imaging (MRI) and antitumor activity of complex nanoparticles were evaluated in tumor-bearing nude mice.MATERIALS AND METHODSCytotoxicity of Fe3O4@PDA-PEG-cRGD-DOX against HCT-116 cells was determined by cck-8 assay. Cellular uptake was measured by confocal laser scanning microscope (CLSM). Pharmacokinetic performance of DOX was evaluated to compare the differences between free DOX and DOX in nanocarrier. Performance in magnetic resonance imaging (MRI) and antitumor activity of complex nanoparticles were evaluated in tumor-bearing nude mice.Fe3O4@PDA-PEG-cRGD-DOX has a particle size of 200-300 nm and a zeta potential of 22.7 mV. Further studies in vitro and in vivo demonstrated their excellent capacity to target tumor cells and promote drug internalization, and significantly higher cytotoxicity with respect to that seen in a control group was shown for the nanoparticles. In addition, they have good thermal stability, photothermal conversion efficiencies (PCEs) and pH responsiveness, releasing more DOX in a mildly acidic environment, which is very conducive to their chemotherapeutic effectiveness in the tumor microenvironment. Fe3O4@PDA-PEG-cRGD-DOX NPs were used in a subcutaneous xenograft tumor model of nude mouse HCT-116 cells showed clear signal contrast in T2-weighted images and effective anti-tumor chemo-photothermal therapy under NIR irradiation.RESULTSFe3O4@PDA-PEG-cRGD-DOX has a particle size of 200-300 nm and a zeta potential of 22.7 mV. Further studies in vitro and in vivo demonstrated their excellent capacity to target tumor cells and promote drug internalization, and significantly higher cytotoxicity with respect to that seen in a control group was shown for the nanoparticles. In addition, they have good thermal stability, photothermal conversion efficiencies (PCEs) and pH responsiveness, releasing more DOX in a mildly acidic environment, which is very conducive to their chemotherapeutic effectiveness in the tumor microenvironment. Fe3O4@PDA-PEG-cRGD-DOX NPs were used in a subcutaneous xenograft tumor model of nude mouse HCT-116 cells showed clear signal contrast in T2-weighted images and effective anti-tumor chemo-photothermal therapy under NIR irradiation.According to our results, Fe3O4@PDA-PEG-cRGD-DOX had a satisfactory antitumor effect on colon cancer in nude mice and could be further developed as a potential integrated platform for the diagnosis and treatment of cancer to improve its antitumor activity against colon cancer.CONCLUSIONAccording to our results, Fe3O4@PDA-PEG-cRGD-DOX had a satisfactory antitumor effect on colon cancer in nude mice and could be further developed as a potential integrated platform for the diagnosis and treatment of cancer to improve its antitumor activity against colon cancer.

Granny has built a splendid vegetable garden from scratch on the rooftop of her Chengdu apartment building, and when harvest time comes she gives the extra produce to her neighbors and cooks a delicious feast for her family.

Urban agglomeration, an established urban spatial pattern, contributes to the spatial association and dependence of city-level CO2 emission distribution while boosting regional economic growth. Exploring this spatial association and dependence is conducive to the implementation of effective and coordinated policies for regional level CO2 reduction. This study calculated CO2 emissions from 2005–2016 in the Chengdu-Chongqing urban agglomeration with the IPAT model, and empirically explored the spatial structure pattern and association effect of CO2 across the area leveraged by the social network analysis. The findings revealed the following: (1) The spatial structure of CO2 emission in the area is a complex network pattern, and in the sample period, the CO2 emission association relations increased steadily and the network stabilization remains strengthened; (2) the centrality of the cities in this area can be categorized into three classes: Chengdu and Chongqing are defined as the first class, the second class covers Deyang, Mianyang, Yibin, and Nanchong, and the third class includes Zigong, Suining, Meishan, and Guangan—the number of cities in this class is on the rise; (3) the network is divided into four subgroups: the area around Chengdu, south Sichuan, northeast Sichuan, and west Chongqing where the spillover effect of CO2 is greatest; and (4) the higher density of the global network of CO2 emission considerably reduces regional emission intensity and narrows the differences among regions. Individual networks with higher centrality are also found to have lower emission intensity.

With rapid urbanization and industrialization, ecological disorders and environmental degradation have become serious, and the promotion of the coordinated development of the social economy and ecological environment is not only a pressing problem to be solved, but also an important step towards sustainable development. The coordinated development of the social economy and eco-environment is conducive to sustainable development. Considering the Chengdu–Chongqing urban agglomeration as a case study, this paper adopts panel data and establishes an index system to evaluate the coupling coordination degree (CCD) between the social economy and ecological environment based on the concept of high-quality development. From the perspective of time and space, the changing laws and characteristics of the CCD are analyzed, and the key factors affecting it are determined using regression analysis. The results show the following: (1) the CCD between the social economy and ecological environment of the Chengdu–Chongqing urban agglomeration presents a low level overall; (2) the CCD in more developed regions is significantly higher than that in less developed regions; thus, the characteristics of spatial differences are obvious; (3) the urbanization rate, ratio of actual use of foreign capital and GDP, ratio of total export-import volume and GDP, proportion of days with good air quality, and per capita public green space area are the main factors affecting the coordinated development of the social economy and ecological environment in the Chengdu–Chongqing urban agglomeration; and (4) Chongqing has obvious endogeneity. Finally, corresponding policy recommendations are provided aimed at promoting rapid economic development in the Chengdu–Chongqing urban agglomeration while focusing on environmental protection and promoting high-quality economic development with ecological environmental protection, while putting forward decision-making suggestions for high-quality development of urban agglomerations.

In the context of uneven development studies of China, urban built-up area changes are the index of the impact of power, as the local government is the only party that is able to acquire agricultural land and convert it to construction urban land. Existing studies generally use statistical data to describe the built-up area changes and struggle to meet the requirement of an updated and inexpensive monitoring of uneven development, especially for western cities with tight budgets. Open access NPP-VIIRS (Suomi National Polar-orbiting Partnership Visible Infrared Imaging Radiometer Suite), NDVI (Normalized Difference Vegetation Index), and nighttime LST (Land Surface Temperature) data ranging from 2015 to 2019 were analyzed with a stratified SVM (Support Vector Machine) method in this study to track urban built-up area changes in Chengdu, one of the biggest cities in Western China. The SDE (Standard Deviation Ellipse) and Moran’s I were then applied to evaluate the spatial variations of the built-up area changes. It was revealed that the spatial evolution of built-up area change in Chengdu over the period 2015–2019 demonstrated a “northwest-southeast” spatial expansion pattern, and the change distance in the center of gravity in 2018 and 2019 was greater than that from 2015 to 2017, which reflected the faster uneven development in 2018 and 2019 in Chengdu. The results were verified with finer resolution Landsat-8 OLI images; the high OA (all larger than 92%) and KAPPA (all larger than 0.6) values showed the accuracy of the method. The methodology proposed in this study offers a practical way for cities with tight budgets to monitor uneven development, and this study suggests a further adaption using higher-resolution remote sensing images and field experiments.