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The International Commission on Radiological Protection (ICRP) issued its Publication 137, Occupational Intakes of Radionuclides: Part 3 in which the radon equilibrium factor is fixed as 0.4 for tourist caves; however, several studies have reported a different value for the factor and its seasonal variation has also been observed. In this study, the radon concentration, equilibrium equivalent radon concentration and meteorological data were measured, and the equilibrium factor was evaluated in a tourist cave, Gyokusen-do Cave located in the southern part of Okinawa Island in southwestern Japan. Radon concentrations were measured with an AlphaGUARD and their corresponding meteorological data were measured with integrated sensors. Equilibrium equivalent radon concentration was measured with a continuous air monitor. The measured radon concentrations tended to be low in winter and high in summer, which is similar to previously obtained results. By contrast, the equilibrium factor tended to be high in winter (0.55 ± 0.09) and low in summer (0.24 ± 0.15), with a particularly large fluctuation in summer. It was concluded that measurements in different seasons are necessary for proper evaluation of radon equilibrium factor.

Many studies have supported the efficacy of multi-sensory environment (MSE) interventions in reducing behavioral and psychological symptoms and improving the quality of life for disabled patients. However, it is difficult to identify the groups that are helped and those who are harmed. This study verified the effect of multi-sensory environment interventions on disabled patients by using thermal images, then addressed the precaution using electrocardiography (ECG). Twenty disabled patients participated in experiments for 12 min: ten with muscular dystrophy (MD) and ten with severe motor and intellectual disabilities (SMID). The continuous measurement of nasal temperature evaluated the emotional arousal after facial detection. The QT-RR relation was used to assess the risk degree. It was found that the continuous measurement of nasal temperature enabled us to evaluate the emotional arousal of disabled patients in MSE with the comparison of ECG. Through the QT-RR relation, it was found that the risk assessment for the patient with SMID was 11 times higher than those with MD because the QT was below 300 ms. Therefore, it was concluded that the specification for the risky group was related to the kind of prescribed medication through continuous measurement.

We present a formulation of measurement-based feedback control of a single quantum particle in one spatial dimension to consider arbitrary linear combinations of the position and momentum of the particle used as observables for monitoring and as generators of unitary feedback with strength proportional to the measured signal. We derive a feedback master equation and discuss a general approach to computing the steady-state solutions for arbitrary potentials. For a quantum harmonic oscillator or a free particle, we show that it is possible to cool and confine the system using feedback that simultaneously damps the measured observable and its conjugate momentum. Our general approach allows to identify a combination of measurement and feedback variables that, under certain circumstances, completely mitigates the noise induced by the measurement. The resulting deterministic evolution of expectation values in each realisation of the measurement resembles the dynamics of a damped classical oscillator, leading to a stationary state centred at the minimum of the potential, which becomes the ground state in the weak measurement limit. Remarkably, this stabilisation can be achieved using a fixed generator of feedback that is determined by the asymptotic values of the second-order moments of the steady state. In addition, we demonstrate that appropriate feedback adds a quadratic term in the measured observable to the Hamiltonian of the system. Moreover, we provide an argument for the possibility to cool systems with arbitrary potentials, provided that the measurement is strong enough to localise the particle on an interval smaller than the characteristic length scale of the potential.

Reliable and timely assessment of bone union between vertebrae is considered a key challenge after spinal fusion surgery. Recently, a novel sensor concept demonstrated the ability to objectively assess posterolateral fusion based on continuous implant load monitoring. The aim of this study was to investigate systematically the concept in a mono-segmental fusion model using an updated sensor setup. Three sheep underwent bilateral facetectomy at level L2-L3 and L4-L5. The segments were stabilized using two unconnected pedicle-screw-rod constructs per level. Sensing devices were attached to the rods between each pedicle screw pair and the loads were continuously monitored over 16 weeks. After euthanasia, the spines were biomechanically tested for their range of motion and high-resolution CT scans were performed to confirm the fusion success. After an initial increase in implant load until reaching a maximum (100 %) at approximately week 4, eleven out of twelve sensors measured a constant decrease in implant load to 52 ± 9 % at euthanasia. One sensor measurement was compromised by newly forming bone growing against the sensor clamp. Bridging bone at each facet and minor remnant segmental motion (<0.7°) confirmed the fusion of all motion segments. Data obtained by continuous measurement of implant loading of spinal screw-rod constructs enables objective monitoring of spinal fusion progression. The sensor concept provides valuable real-time information, offering quantifiable data as an alternative to traditional imaging techniques. However, the design of the current sensor concept needs to be matured, tailored to, and validated for the human spine.

Temperature estimation plays a vital role across natural sciences. A standard approach is provided by probe thermometry, where a probe is brought into contact with the sample and examined after a certain amount of time has passed. In situations where, for example, preparation of the probe is non-trivial or total measurement time of the experiment is the main resource that must be optimized, continuously monitoring the probe may be preferred. Here, we consider a minimal model, where the probe is provided by a two-level system coupled to a thermal reservoir. Monitoring thermally activated transitions enables real-time estimation of temperature with increasing accuracy over time. Within this framework we comprehensively investigate thermometry in both bosonic and fermionic environments employing a Bayesian approach. Furthermore, we explore adaptive strategies and find a significant improvement on the precision. Additionally, we examine the impact of noise and find that adaptive strategies may suffer more than non-adaptive ones for short observation times. While our main focus is on thermometry, our results are easily extended to the estimation of other environmental parameters, such as chemical potentials and transition rates.

Introduction: Intra-abdominal pressure (IAP) monitoring is crucial for the detection and prevention of intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS). In the 1970s, air-filled catheters (AFCs) for urodynamic studies were introduced as a solution to overcome the limitations of water-perfused catheters. Recent studies have shown that for correct IAP measurement with traditional AFC, the bladder needs to be primed with 25 mL of saline solution to allow pressure wave transmission to the transducer outside of the body, which limits continuous IAP monitoring. Methods: In this study, a novel triple balloon, air-filled TraumaGuard (TG) catheter system from Sentinel Medical Technologies (Jacksonville, FL, USA) with a unique balloon-in-balloon design was evaluated in a porcine and cadaver model of IAH via laparoscopy (IAPgold). Results: In total, 27 and 86 paired IAP measurements were performed in two pigs and one human cadaver, respectively. The mean IAPTG was 20.7 ± 10.7 mmHg compared to IAPgold of 20.3 ± 10.3 mmHg in the porcine study. In the cadaver investigation, the mean IAPTG was 15.6 ± 10.8 mmHg compared to IAPgold of 14.4 ± 10.4 mmHg. The correlation, concordance, bias, precision, limits of agreement, and percentage error were all in accordance with the WSACS (Abdominal Compartment Society) recommendations and guidelines for research. Conclusions: These findings support the use of the TG catheter for continuous IAP monitoring, providing early detection of elevated IAP, thus enabling the potential for prevention of IAH and ACS. Confirmation studies with the TraumaGuard system in critically ill patients are warranted to further validate these findings.

Respiration rate (RR) is 1 of the physiological responses used to gauge the level of heat stress in cattle. Respiration rate is usually measured by counting chest movement of the animal. This procedure has some disadvantages including that the person who is doing the counting must be trained to ensure accurate results, the animals must be preconditioned to the presence of the observer, and the presences of the observer may influence the behavior and activity of the animals or their position in the pen. In this study, a device that continuously records RR without restraining the animal was developed. The device is lightweight, cheap, easy to install, and more importantly, does not interfere with the activities of the animal. The device is mounted in a halter and is placed around the neck of the subject. The device measures air temperature near the nostrils of the animal and RR is calculated as the number of oscillations of the temperature. The RR measured by the device were compared against RR observed by counting the flank movement (for 60 s, repeated every 10 min) of 5 Nellore cattle, 1 animal per d, and the results show no statistical difference ( = 0.45) between the 2 methods. This demonstrates that this device can be used to continuously measure RR of cattle under field conditions.

Excess CO2 accumulated in soils is typically transported to the atmosphere through molecular diffusion along a concentration gradient. Because of the slow and constant nature of this process, a steady state between peat CO2 production and emissions is often established. However, in peatland ecosystems, high peat porosity could foster additional non-diffusive transport processes, whose dynamics may become important to peat CO2 storage, transport and emission. Based on a continuous record of in situ peat pore CO2 concentration within the unsaturated zone of a raised bog in southern Canada, we show that changes in wind speed create large diel fluctuations in peat pore CO2 store. Peat CO2 builds up overnight and is regularly flushed out the following morning. Persistently high wind speed during the day maintains the peat CO2 with concentrations close to that of the ambient air. At night, wind speed decreases and CO2 production overtakes the transport rate leading to the accumulation of CO2 in the peat. Our results indicate that the effective diffusion coefficient fluctuates based on wind speed and generally exceeds the estimated molecular diffusion coefficient. The balance between peat CO2 accumulation and transport is most dynamic within the range of 0–2 m s−1 wind speeds, which occurs over 75% of the growing season and dominates night-time measurements. Wind therefore drives considerable temporal dynamics in peat CO2 transport and storage, particularly over sub-daily timescales, such that peat CO2 emissions can only be directly related to biological production over longer timescales.

Many of the most fundamental observables—position, momentum, phase point, and spin direction—cannot be measured by an instrument that obeys the orthogonal projection postulate. Continuous-in-time measurements provide the missing theoretical framework to make physical sense of such observables. The elements of the time-dependent instrument define a group called the instrumental group (IG). Relative to the IG, all of the time dependence is contained in a certain function called the Kraus-operator density (KOD), which evolves according to a classical Kolmogorov equation. Unlike the Lindblad master equation, the KOD Kolmogorov equation is a direct expression of how the elements of the instrument (not just the total quantum channel) evolve. Shifting from continuous measurements to sequential measurements more generally, the structure of combining instruments in sequence is shown to correspond to the convolution of their KODs. This convolution promotes the IG to an involutive Banach algebra (a structure that goes all the way back to the origins of POVM and C*-algebra theory), which will be called the instrumental group algebra (IGA). The IGA is the true home of the KOD, similar to how the dual of a von Neumann algebra is the true home of the density operator. Operators on the IGA, which play the analogous role for KODs as superoperators play for density operators, are called ultraoperators and various important examples are discussed. Certain ultraoperator–superoperator intertwining relationships are also considered throughout, including the relationship between the KOD Kolmogorov equation and the Lindblad master equation. The IGA is also shown to have actually two distinct involutions: one respected by the convolution ultraoperators and the other by the quantum channel superoperators. Finally, the KOD Kolmogorov generators are derived for jump processes and more general diffusive processes.

The authors report their initial clinical results with a novel wireless ocular telemetry sensor (OTS) (Sensimed AG, Switzerland) for continuous intraocular pressure (IOP) monitoring in patients with open angle glaucoma. This was a prospective, observational cohort of 15 patients. The OTS is a disposable silicone contact lens with an embedded micro-electromechanical system, which measures changes in corneal curvature induced by variations in IOP. An antenna, mounted around the eye, receives the data, which are then transmitted to a recorder. A signal was recorded in all patients. Thirteen (87%) patients completed 24-h IOP monitoring: one patient discontinued IOP monitoring due to device intolerance, and incomplete recordings were obtained in a second patient due to technical device malfunction. In 9/13 (69%) patients, the highest signals were recorded during the nocturnal period. No serious adverse events were recorded. The OTS shows good safety and functionality to monitor IOP fluctuations in patients over 24 h. This technology has the potential to provide hitherto unobtainable data on the chronobiology of IOP, possibly leading to improved care of glaucoma patients.