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Every time I go on vacation, someone dies : a novel
\"Ten days, eight suspects, six cities, five authors, three bodies . . . one trip to die for. All that bestselling author Eleanor Dash wants is to get through her book tour in Italy and kill off her main character, Connor Smith, in the next in her Vacation Mysteries series--is that too much to ask? Clearly, because when an attempt is made on the real Connor's life--the handsome but infuriating con man she got mixed up with ten years ago and now can't get out of her life--Eleanor's enlisted to help solve the case. Contending with literary rivals, rabid fans, a stalker--and even her ex, Oliver, who turns up unexpectedly--theories are bandied about, and rivalries, rifts, and broken hearts are revealed. But who's really trying to get away with murder? Every Time I Go on Vacation, Someone Dies is the irresistible and hilarious series debut from Catherine Mack, introducing bestselling fictional author Eleanor Dash on her Italian book tour that turns into a real-life murder mystery, as her life starts to imitate the world in her books\"-- Provided by publisher.
Book
Effectiveness of DASH Diet versus Other Diet Modalities in Patients with Metabolic Syndrome: A Systematic Review and Meta-Analysis
Background: Metabolic syndrome refers to the coexistence of several known cardiovascular risk factors, including insulin resistance, obesity, atherogenic dyslipidemia, and hypertension. These conditions are interrelated and share underlying mediators, mechanisms, and pathways. Improvement in dietary habits has been shown to improve metabolic parameters in patients undergoing treatment with different diets. Methods: A systematic search in different databases was realized using the keywords “Metabolic syndrome”, “X syndrome”, “Dash dietary” and “Dash diet”. Finally, six studies were included in this meta-analysis. Results: All articles comparing the DASH diet vs. other diet modalities reported significant differences in favor of the DASH diet on Systolic blood pressure (SBP) (standardized mean difference [SMD] = −8.06, confidence interval [CI] = −9.89 to −7.32, and p < 0.00001), Diastolic blood pressure (SMD = −6.38, CI = −7.62 to −5.14, and p < 0.00001), Cholesterol HDL (SMD = 0.70, CI = 0.53 to 0.88, and p < 0.00001) and Cholesterol LDL (SMD = −1.29, CI = −1.73 to −0.85, and p < 0.00001) scales. Conclusions: The DASH diet has been shown to be beneficial in altered parameters in patients with MS, and the resulting improvements can significantly affect the daily health of these patients. We therefore recommend that professionals who manage these pathologies promote the use of the DASH diet for the management of specific symptoms.
Journal Article
The relation between MIND diet with psychological disorders and psychological stress among Iranian adults
Background
Given the role of dietary antioxidants in relieving depression, anxiety, and stress, as well as studies on the beneficial effects of the Mediterranean and Dash diets separately on these problems, in this study, we examine the relationship between the MIND index (Mediterranean- DASH diet Intervention for Neurodegenerative Delay) as a combined indicator of the Mediterranean and DASH diet with psychological disorders such as depression, anxiety, and psychological stress among a large sample of the Iranian adult population.
Methods
This cross-sectional study was performed on 7165 participants of the enrollment phase of Yazd Health Study (YaHS) and Yazd Nutrition Study (TAMYZ) a valid 178-item semi-quantitative food frequency questionnaire (FFQ) was used to assess participants’ food intake. The MIND diet score was calculated based on participants’ dietary intakes obtained from FFQ. Also, the valid Iranian version of the Depression, Anxiety, and Stress Scale (DASS 21) was used to assess psychological disorders and stress. In addition, the association between the MIND diet and psychological disorders and stress was assessed through logistic regression.
Results
The mean ± SD score was 3.33 ± 3.79 for depression, 2.99 ± 3.65 for anxiety, and 5.93 ± 4.70 for psychological stress. The mean score of MIND in this study was 7.56. After adjustment for after adjusting for age, gender, intake of energy, BMI, history of chronic disease, marital status, education level, smoking history, physical activity level, pregnancy or lactation, intakes of dietary EPA, DHA, and fiber, individuals in highest compared to the lowest quartile of MIND diet score had significantly lower odds of depression (OR = 0.62, 95% CI 0.40 – 0.96; P-trend = 0.02) and anxiety (OR = 0.61, 95% CI 0.41 – 0.91; P-trend = 0.01). However, no significant association was observed for psychological stress (OR = 0.57, 95% CI 0.28 – 1.14; P-trend = 0.83).
Conclusion
Therefore, it seems that following the MIND diet can prevent the possibility of these psychological problems. However, there is a need to design studies with more robust methodologies such as clinical trial studies.
Journal Article
Validation of a MIND diet screener in older adults
INTRODUCTION Higher adherence to the Mediterranean‐DASH (Dietary Approaches to Stop Hypertension) Intervention for Neurodegenerative Delay (MIND) diet has been associated with reduced Alzheimer's disease (AD) risk. This study assessed the validity of a brief 15‐item MIND diet screener compared to a comprehensive food frequency questionnaire (FFQ). METHODS The validity of an adapted MIND diet screener relative to the VioScreen FFQ was evaluated in 92 older adults from the Indiana Alzheimer's Disease Research Center (IADRC). Correlation coefficients and tertile‐based classification statistics were used, and FFQ nutrient profiles were examined across screener‐based MIND diet tertiles. RESULTS MIND diet scores from the screener showed strong positive correlation (r = 0.71, ρ = 0.70, p < 0.001) and comparable ranking ability (63% correctly classified, 1% grossly misclassified, kw = 0.67) compared to those from the FFQ, as well as significant associations with nutrient profiles. CONCLUSION The MIND diet screener is an acceptable, time‐efficient tool for estimating MIND diet scores in older adults. Highlights The MIND diet screener effectively differentiated participants by diet quality. Agreement between instrument scores was consistent across diagnostic groups. Reliability of the screener over approximately 1 year was comparable to the FFQ. The MIND diet screener is an acceptable tool for use in time‐constrained settings. Future studies should confirm validity using objective biomarkers.
Journal Article
Cryptozoo , dir. Dash Shaw
This is a flm review of Cryptozoo (2021), directed by Dash Shaw. Keywords Mythological creatures, Environmentalism
Journal Article
Dietary Strategies for Metabolic Syndrome: A Comprehensive Review
Metabolic syndrome is a cluster of metabolic risk factors, characterized by abdominal obesity, dyslipidemia, low levels of high-density lipoprotein cholesterol (HDL-c), hypertension, and insulin resistance. Lifestyle modifications, especially dietary habits, are the main therapeutic strategy for the treatment and management of metabolic syndrome, but the most effective dietary pattern for its management has not been established. Specific dietary modifications, such as improving the quality of the foods or changing macronutrient distribution, showed beneficial effects on metabolic syndrome conditions and individual parameters. On comparing low-fat and restricted diets, the scientific evidence supports the use of the Mediterranean Dietary Approaches to Stop Hypertension (DASH) diet intervention as the new paradigm for metabolic syndrome prevention and treatment. The nutritional distribution and quality of these healthy diets allows health professionals to provide easy-to-follow dietary advice without the need for restricted diets. Nonetheless, energy-restricted dietary patterns and improvements in physical activity are crucial to improve the metabolic disturbances observed in metabolic syndrome patients.
Journal Article
Adherence to Mediterranean, DASH, Mediterranean-DASH intervention for neurodegenerative delay
This study examined the association of psychological symptoms with adherence to Mediterranean (MED), dietary approach to stop hypertension (DASH), and Mediterranean-DASH intervention for neurodegenerative delay (MIND) diets, and serum 25(OH)D levels in Iranian adults. In this cross-sectional study, 527 adults aged 20-65 years were assessed. Dietary intake was collected using a validated 168-item food frequency questionnaire. Serum 25-hydroxy vitamin D levels were measured, and psychological symptoms were evaluated using standard questionnaires. Multivariable logistic regression was conducted with adjustment for confounders. In the fully-adjusted model, subjects in the highest vs. lowest tertile of MED (OR = 0.21; 95%CI: 0.08-0.48), DASH (OR = 0.35; 95%CI: 0.16-0.78), and MIND (OR = 0.20; 95%CI: 0.09-0.45) diets had lower odds of reporting depressive symptoms. Participants in the top vs. bottom tertile of MED (OR = 0.12; 95%CI: 0.02-0.67), DASH (OR = 0.16; 95%CI: 0.03-0.85), and MIND (OR = 0.07; 95%CI: 0.01-0.63) diets also exhibited 88%, 84%, and 93% lower odds of reporting anxiety symptoms. An inverse significant association has been found between the MED diet and odds of distress (OR = 0.39; 95%CI: 0.21-0.72). However, no significant relationship has been found between the DASH and MIND diets with psychological distress. Serum vitamin D, classified as sufficient, insufficient, deficient, or severely deficient, showed no significant association with psychological symptoms in crude or adjusted analyses. Adherence to healthy dietary patterns was associated to lower odds of depressive and anxiety symptoms. No significant link was found for vitamin D. Causality cannot be inferred due to the cross-sectional design.
Journal Article
Anti-Inflammatory Nutrients and Obesity-Associated Metabolic-Inflammation: State of the Art and Future Direction
Growing evidence supports the hypothesis that dietary factors may play a role in systemic low-grade chronic inflammation. Summary evidence from randomized controlled trials has shown substantial effects on biomarkers of inflammation following the adoption of plant-based diets (including, but not limited to, the Mediterranean diet), while consistent findings have been reported for higher intakes of whole grains, fruits, and vegetables and positive trends observed for the consumption of legumes, pulses, nuts, and olive oil. Among animal food groups, dairy products have been shown to have the best benefits on biomarkers of inflammation, while red meat and egg have been shown to have neutral effects. The present review provides an overview of the mechanisms underlying the relation between dietary factors and immune system, with a focus on specific macronutrient and non-nutrient phytochemicals (polyphenols) and low-grade inflammation. Substantial differences within each macronutrient group may explain the conflicting results obtained regarding foods high in saturated fats and carbohydrates, underlying the role of specific subtypes of molecules (i.e., short-chain fatty acids or fiber vs. long chain fatty acids or free added sugars) when exploring the relation between diet and inflammation, as well as the importance of the food matrix and the commixture of foods in the context of whole dietary patterns. Dietary polyphenols and oligopeptides have been hypothesized to exert several functions, including the regulation of the inflammatory response and effects on the immune system. Overall, evidence suggests that dietary factors may affect the immune system regardless of obesity-related inflammation.
Journal Article
Association between adherence to Dietary Approach to Stop Hypertension (DASH) diet with sleep quality, sleep duration, inflammation, and oxidative stress among Iranian adults
Background
We aimed to evaluate the relationship between Dietary Approach to Stop Hypertension (DASH) diet adherence and sleep quality, quantity, inflammation, and oxidative stress in Iranian adults.
Methods
This cross-sectional research was carried out in 2021 and 535 individuals contributed to the present analysis. Using a standardized 168-item food frequency questionnaire, we assessed the subjects’ typical dietary intakes and estimated DASH score. Pittsburgh Sleep Quality Index (PSQI) was employed to assess both quantity and quality of sleep. Serum inflammatory and oxidative stress biomarkers were measured through fasting blood sampling.
Results
Higher adherence to DASH (vs. lower adherence) was inversely associated with poor sleep quality and short sleeping [fully-adjusted model for poor sleep quality: OR
T3 vs. T1
= 0.64; 95%CI: 0.44–0.94; for short sleeping: OR
T3 vs. T1
= 0.66; 95%CI: 0.45–0.96]. These relations were observed particularly in women [fully-adjusted model for poor sleep quality: OR
T3 vs. T1
= 0.14; 95%CI: 0.04–0.56; for short sleeping: OR
T3 vs. T1
= 0.12; 95%CI: 0.03–0.55]. Moreover, moderate and higher adherences to DASH diet were respectively linked to a lower odds of two sleep quality domains: delay in falling asleep [fully-adjusted model: OR
T2 vs. T1
= 0.39; 95%CI: 0.15–0.98], and sleep disorders [fully-adjusted model: OR
T3 vs. T1
= 0.26; 95%CI: 0.08–0.84]. In the fully adjusted model, no link was found between adherence to the DASH diet and biomarkers of inflammation or oxidative stress (
p
≥ 0.05).
Conclusion
Among studied middle-aged Iranian population, adherence to DASH dietary pattern was associated with improved sleep quality and quantity, especially in women. None of the biomarkers acted as mediators in these relationships.
Trial registration
Not applicable.
Journal Article