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Relationship between Phenolic Compounds and Antioxidant Activity of Some Moroccan Date Palm Fruit Varieties (Phoenix dactylifera L.): A Two-Year Study
In Morocco, the abundance of low-value varieties in the oases may provide an opportunity to capitalize on this richness to create new nutraceutical food products. In this context, the phenolic profile and antioxidant capacity of four Moroccan date varieties were analyzed. Our results indicate that the levels of total polyphenols, total flavonoids and total condensed tannins vary, respectively, from 91.86 to 364.35 mg GAE/100 g of dry weight (DW), 46.59 to 111.80 mg QE/100 g DW and 16.10 to 42.03 mg CE/100 g DW during the 2021 harvest season. Furthermore, during the 2022 harvest season, these contents vary, respectively, from 119.13 to 410.39 mg GAE/100 g DW, 59.30 to 110.85 mg QE/100 g DW and 21.93 to 53.95 mg CE/100 g DW. The results of the HPLC-UV-VIS analysis revealed that, in all four varieties, gallic acid was and remained one of the major compounds in the date extracts. In addition, a high antioxidant activity of date extracts was particularly observed in the three tests, namely ferric reducing power (FRAP), ferrous ion chelating capacity (FIC) and the phosphomolybdate test. This richness in phenolic compounds makes low-value dates a source of active ingredient that can replace the synthetic antioxidants used in the food and pharmaceutical industries.
Journal Article
Crop planting dates: an analysis of global patterns
To assemble a data set of global crop planting and harvesting dates for 19 major crops, explore spatial relationships between planting date and climate for two of them, and compare our analysis with a review of the literature on factors that drive decisions on planting dates. Global. We digitized and georeferenced existing data on crop planting and harvesting dates from six sources. We then examined relationships between planting dates and temperature, precipitation and potential evapotranspiration using 30-year average climatologies from the Climatic Research Unit, University of East Anglia (CRU CL 2.0). We present global planting date patterns for maize, spring wheat and winter wheat (our full, publicly available data set contains planting and harvesting dates for 19 major crops). Maize planting in the northern mid-latitudes generally occurs in April and May. Daily average air temperatures are usually c. 12-17 °C at the time of maize planting in these regions, although soil moisture often determines planting date more directly than does temperature. Maize planting dates vary more widely in tropical regions. Spring wheat is usually planted at cooler temperatures than maize, between c. 8 and 14 °C in temperate regions. Winter wheat is generally planted in September and October in the northern mid-latitudes. In temperate regions, spatial patterns of maize and spring wheat planting dates can be predicted reasonably well by assuming a fixed temperature at planting. However, planting dates in lower latitudes and planting dates of winter wheat are more difficult to predict from climate alone. In part this is because planting dates may be chosen to ensure a favourable climate during a critical growth stage, such as flowering, rather than to ensure an optimal climate early in the crop's growth. The lack of predictability is also due to the pervasive influence of technological and socio-economic factors on planting dates.
Journal Article
Statistical Inference of Prehistoric Demography from Frequency Distributions of Radiocarbon Dates: A Review and a Guide for the Perplexed
The last decade saw a rapid increase in the number of studies where time–frequency changes of radiocarbon dates have been used as a proxy for inferring past population dynamics. Although its universal and straightforward premise is appealing and undoubtedly offers some unique opportunities for research on long-term comparative demography, practical applications are far from trivial and riddled with issues pertaining to the very nature of the proxy under examination. Here I review the most common criticisms concerning the nature of radiocarbon time–frequency data as a demographic proxy, focusing on key statistical and inferential challenges. I then examine and compare recent methodological advances in the field by grouping them into three approaches: reconstructive, null-hypothesis significance testing, and model fitting. I will then conclude with some general recommendations for applying these techniques in archaeological and paleo-demographic research.
Journal Article
Vehicle routing problems over time: a survey
In vehicle routing problems (VRPs) the decisions to be taken concern the assignment of customers to vehicles and the sequencing of the customers assigned to each vehicle. Additional decisions may need to be jointly taken, depending on the specific problem setting. In this paper, after discussing the different kinds of decisions taken in different classes of VRPs, the class where the decision about when the routes start from the depot has to be taken is considered and the related literature is reviewed. This class of problems, that we call VRPs over time, includes the periodic routing problems, the inventory routing problems, the vehicle routing problems with release dates, and the multi-trip vehicle routing problems.
Journal Article
Polyphenol-Rich Date Palm Fruit Seed (Phoenix Dactylifera L.) Extract Inhibits Labile Iron, Enzyme, and Cancer Cell Activities, and DNA and Protein Damage
Date palm fruit seed (Phoenix dactylifera L.) extract (DSE), an under-utilized resource, is a rich source of polyphenols with high potency for disease prevention and antioxidative activities. For the first time, the present study demonstrated that DSE inhibits labile iron activity and DNA and BSA damage and inhibits acetylcholinesterase and tyrosinase activities. Moreover, DSE reduces the proliferation of hepatic, colorectal, and breast cancer cells dose-dependently through apoptotic mechanisms. Furthermore, DSE significantly suppressed the expression of both BCl-2 and P21 genes and increased the P53 expression level when compared with the untreated cells and the 5-FU treated cells. These findings suggest a strong potential for DSE in protecting against the iron-catalyzed ferroptosis that results in programmed cell death. The results also confirm the efficacy of DSE against cancer cells. Therefore, DSE constitutes a valuable candidate for developing functional foods and for natural compound-based chemotherapy for the pharmaceutical and nutraceutical industries.
Journal Article