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WE HAVE GOOD NEWS TO SHARE
With the generous donors and the commitment of the Board of Trustees, the TMS Foundation successfully navigated a volatile economy in 2022, with its year-end appeal efforts posting $186.155-the third best year on record and a marked increase from 2021. While every donation in 2022 made a difference, the Foundation also greatly benefited from acts of extraordinary generosity. In particular, Cady would like to recognize the support of Robyn and Rob Wagoner, TMS Foundation Diamond members, who donated $50,000 in 2022. This is the latest testament to their long-standing, exceptional commitment to the foundation and its important work. It is the belief in the TMS Foundation's mission, as exemplified by Robyn and Rob, that has enabled them to make progress on their strategic goals, which the TMS Foundation Board of Trustees adopted in Feb 2020, just weeks before the global pandemic shutdown. In Nov 2022, the Board of Trustees announced significant progress on two of those goals.
Journal Article
Never let me go
\"As children Kathy, Ruth, and Tommy were students at Hailsham, an exclusive boarding school secluded in the English countryside. It was a place of mercurial cliques and mysterious rules where teachers were constantly reminding their charges of how special they were. Now, years later, Kathy is a a young woman. Ruth and Tommy have reentered her life. And for the first time she is beginning to look back at their shared past and understand just what it is that makes them special--and how that gift will shape the rest of their time together.
Book
Reproductive donation : practice, policy, and bioethics
\"Reproductive donation is the most contentious area of assisted reproduction. Even within Europe there are wide variations in what is permitted in each country. This multidisciplinary book takes a fresh look at the practices of egg, sperm and embryo donation and surrogacy, bringing together ethical analysis and empirical research. New evidence is offered on aspects of assisted reproduction and the families these create, including non-traditional types. One of the key issues addressed is should children be told of their donor origin? If they do learn the identity of their donor, what kinds of relationships may be forged between families, the donor and other donor sibling families? Should donation involve a gift relationship? Is intra-familial donation too close for comfort? How should we understand the growing trend for 'reproductive tourism'? This lively and informed discussion offers new insights into reproductive donation and the resulting donor families\"--Provided by publisher.
Book
Editor's Note
First the tears and the talking, then the rage. Screaming into a pillow, then screaming into the sky, barefoot and throwing dirty snow at the house, the fence, the shed. Mary Clark· Rebecca Cook Marie K. & Lee Dixson· Susan Ferraro Fidelity Charitable Gift Fund· Stephen & Emmie Donadio· Castle Freeman Jr.· Ann Gateley David Griffith Gwendolyn S. Haley· Lindsay Hill· Mary Golding Hogya Lindsey & David Huddle Thomas R. Hummel Lucy & Simeon Hutner· Ann Jones-Weinstock & David Weinstock· Fajer Alexander Khansa Joann Kobin· Michael B. Ledbetter Roxanne M. Leighton· Charles Logan & Abigail G. Mitchell· Emily Mitchell David & Elizabeth Muhlbaum· Charles S. Nelson Paul Northrup· Oaktree Capital Management Anne K. O'Brien· Nancy M. O'Connor Larry I. Palmer· Jared S. Pomerance· Marcia Pomerance Christopher Ross· Jay R. Silverman J. Lea H. Simonds Wanda Smith· Robert B. Stepto Michele M. Surat Sarah D. Thomas Janet Towle Joshua M. Tyree· Nancy Zafris Elizabeth A. Zogby· For more about giving, visit www.nereview.com/support-NER. * True Blue donors who have given for a minimum of three consecutive years.
Journal Article
Mapping Ethical, Legal, and Social Implications (ELSI) of gamete donation
Research questionThis scoping review investigates the Ethical, Legal, and Social Implications (ELSI) of gamete donation, a critical facet of Assisted Reproductive Technologies, by analyzing the evolving research scope, methodological approaches, and the geographical skew in the literature. Despite the increased global uptake of donor gametes, current scholarship predominantly emanates from Western contexts and focuses on majoritized groups. This bias constrains the universality of research findings and limits their applicability across varied legal, cultural, and social contexts, underscoring a need for broader inclusivity.DesignWe addressed 867 pivotal articles published between 1999 and 2019.ResultsOur analysis reveals a discernible escalation in research volume, with 62% based on empirical research. The intellectual landscape unfolds into four dominant clusters: Regulatory Frameworks, Incentives, and Access; Family Dynamics and Genetic Linkages; Identity and Privacy in Donor Conception; and Cultural and Societal Attitudes towards GD. Each cluster highlights nuanced dimensions of gamete donation, from regulatory intricacies and psychological welfare to identity ethics and cultural perceptions.ConclusionOur findings advocate for a shift towards more globally representative and methodologically inclusive research. By integrating diverse cultural narratives and expanding geographical breadth, future research can offer holistic understandings of gamete donation, fostering equitable and culturally resonant practices and policies worldwide.
Journal Article
The story of a heart
The first of our organs to form, the last to die, the heart is both a simple pump and the symbol of all that makes us human: as long as it continues to beat, we hope. One summer day, nine-year-old Keira suffered catastrophic injuries in a car accident. Though her brain and the rest of her body began to shut down, her heart continued to beat. In an act of extraordinary generosity, Keira's parents and siblings agreed that she would have wanted to be an organ donor. Meanwhile nine-year-old Max had been hospitalised for nearly a year with a virus that was causing his young heart to fail. When Max's parents received the call they had been hoping for, they knew it came at a terrible cost to another family. This is the unforgettable story of how one family's grief transformed into a lifesaving gift.
BOOK
Organ donation after circulatory death: current status and future potential
The continuing shortage of deceased donor organs for transplantation, and the limited number of potential donors after brain death, has led to a resurgence of interest in donation after circulatory death (DCD). The processes of warm and cold ischemia threaten the viability of DCD organs, but these can be minimized by well-organized DCD pathways and new techniques of in situ organ preservation and ex situ resuscitation and repair post-explantation. Transplantation survival after DCD is comparable to donation after brain death despite higher rates of primary non-function and delayed graft function. Countries with successfully implemented DCD programs have achieved this primarily through the establishment of national ethical, professional and legal frameworks to address both public and professional concerns with all aspects of the DCD pathway. It is unlikely that expanding standard DCD programs will, in isolation, be sufficient to address the worldwide shortage of donor organs for transplantation. It is therefore likely that reliance on extended criteria donors will increase, with the attendant imperative to minimize ischemic injury to candidate organs. Normothermic regional perfusion and ex situ perfusion techniques allow enhanced preservation, assessment, resuscitation and/or repair of damaged organs as a way of improving overall organ quality and preventing the unnecessary discarding of DCD organs. This review will outline exemplar controlled and uncontrolled DCD pathways, highlighting practical and logistical considerations that minimize warm and cold ischemia times while addressing potential ethical concerns. Future perspectives will also be discussed.
Journal Article