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With Christina Snyder’s essay on removals, we are excited to launch a new regular series for the Journal of the Early Republic: “Engaging Historiography.” The series is an effort to bring more expansive and meaningful discussion of historiography into the journal’s main pages. We are hoping that the pieces we publish will become anchor essays for graduate seminars; provide new ideas for scholars to bring into their classrooms, public exhibits, and research; and ultimately help steer the field. At a time when so much good scholarship is being published in our field, we expect that “Engaging Historiography” will help our readers take stock and participate in valuable conversations.

During the last decade the field of cancer immunotherapy has witnessed impressive progress. Highly effective immunotherapies such as immune checkpoint inhibition, and T-cell engaging therapies like bispecific T-cell engaging (BiTE) single-chain antibody constructs and chimeric antigen receptor (CAR) T cells have shown remarkable efficacy in clinical trials and some of these agents have already received regulatory approval. However, along with growing experience in the clinical application of these potent immunotherapeutic agents comes the increasing awareness of their inherent and potentially fatal adverse effects, most notably the cytokine release syndrome (CRS). This review provides a comprehensive overview of the mechanisms underlying CRS pathophysiology, risk factors, clinical presentation, differential diagnoses, and prognostic factors. In addition, based on the current evidence we give practical guidance to the management of the cytokine release syndrome.

The current study investigates how supervisors’ engaging leadership, as perceived by their employees, increases employees’ job outcomes at the individual and team level, as mediated by (team) work engagement. Job outcome indicators at the team level are team performance, team learning, and team innovation; and at the individual level, job performance, employee learning, and innovative work behavior. The novel concept of engaging leadership is presented as the specific type of leadership to foster (team) work engagement. A multi-level longitudinal study is conducted among 224 blue collar employees nested in 54 teams in an Indonesian state-owned holding company in the agricultural industry using a one-year time lag. The findings show, as expected, that at the team level, engaging leadership at time 1 predicted team learning and team innovation (but not team performance) at time 2, via team work engagement at time 2. Additionally, an expected cross-level effect was observed from engaging leadership at the team level at time 1 predicting individual job performance (but not employee learning and innovative work behavior) at time 2, via team work engagement at time 2. Finally, an expected second cross-level effect was observed for engaging leadership at the team level at time 1, which predicted individual job performance, employee learning, and innovative work behavior at time 2, via work engagement at time 2.

Science is a search for evidence, but science communication must be a search for meaning. General audiences will only care about science if it is presented in a meaningful context. One of the most effective ways to do this is through storytelling. Stories are integral to all cultures. Studies indicate that stories even help audiences to process and recall new information. Scientists sometimes worry that storytelling will conflate empirical evidence with fabrication. But when telling non-fiction stories, it is a process of recognizing the story elements already present in the subject material and distilling the most concise and compelling account for a target audience. In this paper, I review literature, offer examples, and draw from my experience as a scientist and a communication trainer to explore how storytelling makes science comprehensible and meaningful for general audiences.

This study quantified the strain development after inserting implant‐borne fixed dental prosthesis (FDP) to various implant–abutment joints. Two bone‐level implants (∅ = 4.1 mm, RC, SLA 10 mm, Ti, Straumann) were inserted in polyurethane models (N = 3) in the area of tooth nos 44 and 47. Four‐unit veneered zirconium dioxide FDPs (n = 2) were fabricated, one of which was fixed on engaging (E; RC Variobase, ∅ = 4.5 mm, H = 3.5 mm) and the other on non‐engaging (NE) abutments (RC Variobase, ∅ = 4.5 mm, H = 5.5 mm). One strain gauge was bonded to the occlusal surface of pontic no. 46 on the FDP and the other two on the polyurethane model. Before (baseline) and after torque (35 Ncm), strain values were recorded three times. Data were analyzed using Kruskal–Wallis and Mann–Whitney U tests (α = 0.05). Mean strain values presented significant increase after torque for both E and NE implant–abutment connection type (baseline: E = 4.33 ± 4.38; NE = 4.85 ± 4.85; torque: E = 196.56 ± 188.02; NE = 275.63 ± 407.7; p < .05). Mean strain values based on implant level presented significant increase after torque for both E and NE implant–abutment connection (baseline: E = 4.94 ± 5.29; NE = 5.78 ± 5.69; torque: E = 253.78 ± 178.14; NE = 347.72 ± 493.06; p < .05). The position of the strain gauge on implants (p = .895), FDP (p = .275), and abutment connection type (p = .873) did not significantly affect the strain values. Strain levels for zirconium dioxide implant‐borne FDPs were not affected by the implant–abutment connection type.

Background Social participation (SP) may be an effective measure for decreasing frailty risks. This study investigated whether frequency and type of SP is associated with decreased frailty risk among Chinese middle-aged and older populations. Methods Data were derived from the China Health and Retirement Longitudinal Study (CHARLS). Frailty was assessed using the Rockwood’s Cumulative Deficit Frailty Index. SP was measured according to frequency (none, occasional, weekly and daily) and type (interacting with friends [IWF]; playing mah-jong, chess, and cards or visiting community clubs [MCCC], going to community-organized dancing, fitness, qigong and so on [DFQ]; participating in community-related organizations [CRO]; voluntary or charitable work [VOC]; using the Internet [INT]). Smooth curves were used to describe the trend for frailty scores across survey waves. The fixed-effect model ( N  = 9,422) was applied to explore the association between the frequency/type of SP and frailty level. For baseline non-frail respondents ( N  = 6,073), the time-varying Cox regression model was used to calculate relative risk of frailty in different SP groups. Results Weekly (β =  − 0.006; 95%CI: [− 0.009, − 0.003]) and daily (β =  − 0.009; 95% CI: [− 0.012, − 0.007]) SP is associated with lower frailty scores using the fixed-effect models. Time-varying Cox regressions present lower risks of frailty in daily SP group (HR = 0.76; 95% CI: [0.69, 0.84]). SP types that can significantly decrease frailty risk include IWF, MCCC and DFQ. Daily IWF and daily DFQ decreases frailty risk in those aged < 65 years, female and urban respondents, but not in those aged ≥ 65 years, male and rural respondents. The impact of daily MCCC is significant in all subgroups, whereas that of lower-frequent MCCC is not significant in those aged ≥ 65 years, male and rural respondents. Conclusion This study demonstrated that enhancing participation in social activities could decrease frailty risk among middle-aged and older populations, especially communicative activities, intellectually demanding/engaging activities and community-organized physical activities. The results suggested very accurate, operable, and valuable intervening measures for promoting healthy ageing.