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Silos are used worldwide to store granular and powdered materials. Agricultural, food and feed products are commonly stored in silos. However, many questions remain unanswered about how to estimate the pressures applied by the bulk material, which are needed to design and calculate the structure of the silo. The complexity of the laws that govern the mechanical behavior of the stored material along with the low number of experimental stations in the world hinder progress in this field. The aim of this study was to elucidate the relationship of the hopper angle, flow pattern and vertical stress at the cylinder-to-hopper transition in slender silos. Therefore, a set of experiments was conducted on a test station to measure the vertical stress produced by maize at the cylinder-to-hopper transition. Five different hopper angles were used. The experiments comprised the filling, the static phase and the discharge. The results obtained show that the hopper angle influences the vertical stress at the cylinder-to-hopper transition. Some bottom configurations (flat bottom and bottom with an angle of 30°) led to vertical stresses that exceeded the value calculated according to Eurocode 1. It is clear that further experimental studies are still necessary to understand the underlying physical phenomena and the relations between pressures, silo geometry and flow pattern of the stored material.

Conservation of summer forage excess represents a management strategy to meet animals' needs for dry matter in the shortage period, but has been poorly studied. Silage can be used for this purpose. This study analyzed the production of palisade grass silage from pasture subjected to different grazing intensities with and without additive, determining losses by gases and effluents and chemical composition of silage. The experiment was a 4 x 3 factorial completely randomized design, with four replications. The factors were: 1st - herbage allowance of 5% (5 kg dry matter 100 kg-1 of animal weight day-1), 10, 15 and 20%. The pasture was managed under rotational stocking with 35-day grazing cycles (7 days of occupation and 28 days of rest) and 2nd - additives: a) control; b) citrus pulp pellets; c) biological inoculant for grass silage. The forage of palisade grass harvested from pastures subjected to low-intensity grazing showed quantitative and qualitative characteristics for ensiling. However, high humidity and low fermentable carbohydrate require the use of additive, favor the fermentation process and increase the nutritional quality of silage.

Três diferentes tipos de silos de laboratório, confeccionados a partir de baldes plásticos, sacos plásticos e manilhas de concreto com revestimento plástico, em dois diferentes graus de compactação (400 ou 600 kg de silagem/m3), foram comparados com o silo comercial tipo trincheira amostrado a 0, 50 e 100 cm da sua superfície. A planta de milho (27,3% de MS e 8,4% de PB) foi picada, homogeneizada e utilizada para encher quatro silos por tratamento. Depois de abertos, estes foram amostrados para análise da composição bromatológica e perfil fermentativo. Os teores de MS e PB variaram entre os diferentes extratos do silo comercial e foram intermediários nos silos laboratoriais, indicando maior translocação de água e nutrientes naquele do que nestes. Os silos laboratoriais representaram bem os comerciais, quanto aos componentes da parede celular, amido, carboidratos solúveis e DIVMS. O pH foi menor na silagem obtida no extrato médio, intermediário no profundo e maior na superfície do silo comercial. Silagens obtidas no extrato médio também apresentaram maiores teores de nitrogênio amoniacal e ácido lático, enquanto que as obtidas no extrato profundo apresentaram as concentrações mais elevadas de ácido acético. De forma geral, os silos laboratoriais representaram bem o perfil de fermentação dos silos comerciais (pH, concentração de etanol, acético, propiônico, butírico, lático e N amoniacal), já que a maior variabilidade de resposta foi observada entre os extratos do silo comercial

Background The European Reference Network for rare Inherited Congenital Anomalies, ERNICA, guidelines for gastroschisis cover perinatal period to help teams to improve care. Method A systematic literature search including 136 publications was conducted. Research findings were assessed following the GRADE methodology. The evidence to decision framework was used to determine the strength and direction of recommendations. Results The mode or timing of delivery do not impact neonatal mortality, risk of NEC or time on parenteral nutrition (PN). Intra or extra abdominal bowel dilatation predict complex gastroschisis and longer length of hospital stay but not increased perinatal mortality. Outcomes after Bianchi procedure and primary fascia closure under anesthesia are similar. Sutureless closure decreases the rate of surgical site infections and duration of ventilation compared to surgical closure . Silo-staged closure with or without intubation results in similar outcomes. Outcomes of complex gastroschisis (CG) undergoing early or delayed surgical repair are similar. Early enteral feeds starting within 14 days is associated with lower risk of surgical site infection. Recommendations The panel suggests vaginal birth between 37 and 39 w in cases of uncomplicated gastroschisis. Bianchi’s approach is an option in simple gastroschisis. Sutureless closure is suggested when general anesthesia can be avoided, sutured closure. If anesthesia is required. Silo treatment without ventilation and general anesthesia can be considered. In CG with atresia primary intestinal repair can be attempted if the condition of patient and intestine allows. Enteral feeds for simple gastroschisis should start within 14 days.

Purpose Due to the abundant use of granular materials in chemical industries, it is inevitable to store raw materials and products in bulk in silos. For this reason, much research has been carried out in the field of construction, operation and maintenance of silos. One of the important issues that must be investigated in silos is the behavior of their structure when the materials inside them are unloaded. Structural vibrations and the creation of normal noise usually discharge the granular of material from the silo. Both of phenomena are undesirable due to the problems they can cause to the structure and its surroundings. According to the said issues, this paper aims to investigate the vibration problem of the sulfur storage silo of the first refinery during discharge with the help of measuring experimental vibration data and simulating the silo model. Design/methodology/approach In the experimental investigation, the main cause of the vibration of the 400-ton silo in the refinery is used. The mass asymmetry phenomenon when the silo is filled is also considered. The experimental results are authenticated by software analysis too. Findings The results showed that the natural frequency of the ninth mode is almost equal to the natural frequency of sulfur discharge from the silos and has the largest shape change in the structure and vibration range. It is also concluded that the larger sulfur silo (400 tons) should be prioritized over the smaller sulfur silo (200 tons) in the emptying program, and the 400 tons silo should never be emptied even through the 200 tons silo is empty. Originality/value An attempt is made to investigate the issue of vibration in sulfur storage silos in the first refinery of South Pars in the form of experimental investigation and modal analysis.

We present an experimental study of the discharge of a monolayer of a ferromagnetic granular medium in a quasi-2D silo surrounded by vertical uniform magnetic field. We observe that the cohesion induced by the vertical magnetic field tends to canalize the flow above the outlet, modifying its morphology with little incidence on the mass flow rate. Using a direct measurement method of velocities based on particle tracking, we are able to extract an altitude-dependent diffusion length of the granular medium, previously introduced in the kinetic model, and propose a qualitative interpretation of its decay with cohesion.

Blast loadings have become the subject of research in recent decades due to the threats they pose to the surrounding medium. On 4 August 2020, a huge explosion occurred in the Port of Beirut that led to massive damages in the medium surrounding it. Researchers have conducted studies in order to estimate the equivalent explosive mass as well as the damage extent left on structures; however, the studies considered the soil–structure interaction by simple methods. For that, this paper aims to understand the effect of explosion on the grain silo structure present at the port with an emphasis on the soil–structure interaction effects. The structure consists of a group of silos resting on a raft footing that is supported by group of driven piles. A soil–structure model analysis is performed in order to investigate the soil behavior, the damage extent in piles, and the soil–structure interaction due to the Beirut explosion using the CEL (Coupled Eulerian–Lagrangian) approach that suits events involving large deformation. The analysis is performed using the ABAQUS/Explicit FEM software (version 6.14) taking into account the properties of soil medium, the contact algorithm at the soil–structure interface, and the boundary conditions in order to better simulate the real field conditions and ensure accurate results. The work is primarily validated through site data such as the crater size and silo damage.

Interference effects of two adjacent foundations include changing failure mechanism, load settlement, and stress distribution behavior; this can result damages such as differential settlement, tilting, cracking, reduction of serviceability, and even failure. To address these issues, the present study aims to assess the effect of the number of new adjacent building stories on settlement and the tilt of the existing building. The study evaluates the interference effects of two adjacent foundations on sand and fill by finite-element Plaxis 3D in two groups. The first numerical modeling group is conducted in a small scale and compared with laboratory tests that are performed on a 1 g chamber with a height and diameter of 1 m, thickness of 0.01 m, revealing a similar settlement and tilting pattern. The second group is modeled two closely circular footings in full scale. The results showed that the induced settlement increases as the number of stories increases, from 7.5 to 23.5 mm for sand and 25.6 to 38.2 mm for fill, respectively, when the applied load increases from 40 to 100 kN/m 2 . Moreover, in the fill soil, the settlement of the foundation's center was, on average, 167% more than that of sand, with an increase in the number of stories from 4 to 6, and this difference reduced to about 77% in higher stories. Finally, three real cases include “Guilan Residential Building, Grain Silos and Athens Buildings” are evaluated by numerical modeling and induced complications assessed.

The Clinical and Translational Science Award (CTSA) program aims to enhance the quality, efficiency, and impact of translation from discovery to interventions that improve human health. CTSA program hubs at medical research institutions across the United States develop and test innovative tools, methods, and processes, offering core resources and training for the clinical and translational research (CTR) workforce. Hubs have developed services across different domains, such as informatics and pilot studies, to provide expertise and staffing for local research teams. Although these services can provide efficient, cost-effective ways to cover skills gaps and implement rigorous studies, three CTSAs of varying size found the majority of investigators were single domain service users, likely missing opportunities to further enhance their work. Through interviews with CTSA service users and a survey of CTSA service managers, this exploratory study aims to identify barriers to using services from multiple modules and solutions to overcome those barriers. Barriers include challenges in finding information about services, unclear or unknown user needs, and users' lack of funding to engage in services. More issues were identified for the largest CTSA. Although this study represents a small subset of CTSA hubs, we anticipate that our findings and proposed solutions will be relevant to the broader CTSA community. This study provides foundational information can use in their own efforts to increase service utilization and methods that can be used for more comprehensive studies that focus on explaining the relationship between CTSA features and rates of single versus cross-module service use.

Objectives This study aimed to evaluate the efficacy of integrating the open-source large language model (LLM) DeepSeek into problem-based learning (PBL) curriculum for hematology residency training. Methods This non-randomized controlled trial included two groups of 30 s-year hematology residents each. One group received traditional PBL instruction, while the other’s PBL was assisted by DeepSeek. Both groups participated in in-person PBL sessions across two identical hematology courses. The DeepSeek-assisted PBL group utilized DeepSeek V3 and R1 models, along with an AI-facilitated web search and integrated output after automatic information filtering and analysis during their in-person PBL sessions. Learning outcomes were assessed via a post-course survey evaluating effectiveness, credibility, reliability, and engagement. Students also completed five standardized examinations covering analysis and diagnostic decision-making, procedural skills, communication, interdisciplinary integration, and emergency management/ethical considerations. Results The study demonstrated significant advantages of DeepSeek-assisted PBL over traditional PBL across multiple competency domains, including case analysis effectiveness, feedback quality, course structure, and clinical reasoning. Participants also reported stronger curriculum alignment with current guidelines and enhanced capacity for generating clinical insights during discussions. Academically, the DeepSeek-assisted PBL group outperformed in four out of five competency domains (Exams I, III, IV, V), achieving higher total examination scores. However, no significant difference emerged in clinical skills (Exam II), nor did DeepSeek enhance interactive elements based on survey results. Notably, the DeepSeek-assisted PBL group also expressed greater concerns about the potential inaccuracies in artificial intelligence-generated medical advice. Conclusion Integrating DeepSeek into the PBL curriculum may improve clinical competence, diagnostic reasoning, and learner engagement in hematology residency training. These findings suggest that open-source LLMs like DeepSeek may offer scalable and cost-effective support tools to augment traditional medical education. Further study is needed to explore artificial intelligence tools for enhancing interactive elements and procedural skills.