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Mobile Crowd Sensing (MCS) is a novel IoT paradigm where sensor data, as collected by the user’s mobile devices, are integrated with user-generated content, e.g., annotations, self-reports, or images. While providing many advantages, the human involvement also brings big challenges, where the most critical is possibly the poor quality of human-provided content, most often due to the inaccurate input from non-expert users. In this paper, we propose Skeptical Learning, an interactive machine learning algorithm where the machine checks the quality of the user feedback and tries to fix it when a problem arises. In this context, the user feedback consists of answers to machine generated questions, at times defined by the machine. The main idea is to integrate three core elements, which are (i) sensor data, (ii) user answers, and (iii) existing prior knowledge of the world, and to enable a second round of validation with the user any time these three types of information jointly generate an inconsistency. The proposed solution is evaluated in a project focusing on a university student life scenario. The main goal of the project is to recognize the locations and transportation modes of the students. The results highlight an unexpectedly high pervasiveness of user mistakes in the university students life project. The results also shows the advantages provided by Skeptical Learning in dealing with the mislabeling issues in an interactive way and improving the prediction performance.