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3,169 result(s) for "journal club"
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Omicron entry route
Omicron entry route
by Luisanna, Pia , Rowland-Jones, Sarah in Severe acute respiratory syndrome coronavirus 2 , Tropism
2022
Three recent preprints investigate the entry route of SARS-CoV-2 Omicron variant into host cells and its cellular and host tropism.
Journal Article
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Mapping the developmental trajectory and recruitment of memory-phenotype Ly49+CD8+ T cells
Mapping the developmental trajectory and recruitment of memory-phenotype Ly49+CD8+ T cells
by van der Heide, Verena , Trusz, Guillaume J. in 631/136 , 631/250/38 , Biomedical and Life Sciences
2025
A preprint by Laubreton et al. suggests a role for agonist selection and cytokine-driven bystander activation in the differentiation and recruitment of memory-phenotype Ly49+CD8+ T cells.
Journal Article
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Neutrophils are dispensable for Shigella control: macrophages take centre stage
Neutrophils are dispensable for Shigella control: macrophages take centre stage
by Allison, James P. , Ağaç Çobanoğlu, Didem in 631/250/2504 , 631/250/255/1318 , Biomedical and Life Sciences
2025
A preprint by Eislmayr et al. shows that macrophages rather than neutrophils are a key factor in controlling Shigella infection.
Journal Article
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Type 1 immune response reduces seizure risk after traumatic brain injury
Type 1 immune response reduces seizure risk after traumatic brain injury
by Ahn, Jennifer S. Y. , Gommerman, Jennifer L. in 631/250/127/1212 , 692/617/375/364 , Biomedical and Life Sciences
2025
A preprint by Mroz et al. reports a role for IFNgamma in protecting against seizures after traumatic brain injury.
Journal Article
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Identifying memory genes in cancer drug tolerance
Identifying memory genes in cancer drug tolerance
by Chakrabarti, Shaon in 631/67/1813/1634 , 631/67/2329 , Biomedical and Life Sciences
2025
In this Journal Club, Chakrabarti discusses a method to dissect the molecular architecture of inheritable gene expression (memory) states that mark cells that transition into drug-tolerant persister cells in melanoma.
Journal Article
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Podoplanin mediates stromal–immune crosstalk in the lymph node
Podoplanin mediates stromal–immune crosstalk in the lymph node
by Buechler, Matthew B. , McCartney, Erika E. in 631/250/1620/1616 , 631/337/2019 , Biomedical and Life Sciences
2025
A preprint by Makris et al. shows that podoplanin is a key regulator of the functions of fibroblastic reticular cells in lymph nodes, by modulating interactions with immune cells.
Journal Article
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Characterization of the B cell receptor repertoire in melanoma
Characterization of the B cell receptor repertoire in melanoma
by Chung, Junho , Chae, Jisu in 631/250/580 , 631/67/69 , Biomedical and Life Sciences
2025
In this Journal Club, Chae and Chung discuss a study characterizing the differentiation and maturation of both tumour-resident and circulating B cells in patients with melanoma.
Journal Article
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In vivo enhancement of tumour-specific T cells via peptide–MHC-pseudotyped retroviral gene delivery
In vivo enhancement of tumour-specific T cells via peptide–MHC-pseudotyped retroviral gene delivery
by Borrow, Persephone , Kwong, Hugo in 631/61/2300/1850 , 631/67/1059/2325 , Biomedical and Life Sciences
2025
A preprint by Xu et al. shows that MHC-pseudotyped retroviruses can reprogramme, activate and expand tumour-specific T cell populations in vivo.
Journal Article
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Immunoproteasome as a biomarker for immunotherapy
Immunoproteasome as a biomarker for immunotherapy
by Sabarinathan, Radhakrishnan in 631/67/1813/1634 , 631/67/1857 , Biomedical and Life Sciences
2025
In this Journal Club, Sabarinathan discusses a study suggesting immunoproteasome expression as a potential biomarker of response to immune checkpoint inhibition in melanoma.
Journal Article
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Systematic identification of cell state-specific transcription factors in T cells
Systematic identification of cell state-specific transcription factors in T cells
by Ağaç Çobanoğlu, Didem in 631/114/129 , 631/250/580 , Biomedical and Life Sciences
2025
A preprint by Chung et al. presents a framework for the use of transcriptomic and epigenomic data to identify novel transcription factors driving CD8 + T cell states.
Journal Article
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