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The paper describes guidelines for the planning, organization, and successful execution of virtual, global scientific conferences for global audiences. The guidelines are based on experience and lessons learned during the organization of the 3‐day 2020 Virtual Systems Chemistry Symposium hosted on Zoom webinar and Twitter, held on May 2020 with over 1000 registered participants from 46 different countries. This planning guide outlines ten steps that academic organizers can follow to successfully organize and execute virtual, global scientific symposia for global audiences. The authors have also included instructional guides, videos, and PowerPoint slides that can be used as templates or inspiration for hosting virtual symposia with oral presentations on Zoom webinar and poster presentations on Twitter.