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A new series of styryl hemicyanine dyes featuring substituted -phenylpiperazine end groups was synthesized using an environmentally friendly procedure. The photophysical properties of the dyes were systematically investigated in organic solvents of varying polarity and when bound to DNA, using a combination of spectroscopic techniques. The dyes show strong negative solvatochromism and exhibit fluorescence quenching upon DNA binding. The dyes are definitely halochromic, exhibiting pronounced fluorescent acidochromism, accompanied by a photoinduced electron transfer (PET) effect. Titration with acid of the dye-DNA complexes restores fluorescence, indicating suppression of the PET and, at the same time, rigidizing of the chemical structure. UV/VIS and fluorescence titration, circular dichroism spectroscopy, and molecular docking methods were used to investigate the interaction mode between the dyes and DNA. Density functional theory (DFT) and time-dependent density functional theory (TDDFT) quantum chemical calculations were employed in deciphering the observed spectroscopic behavior and PET-related effects. The obtained results suggest the dyes' potential as pH-responsive fluorescent probes for nucleic acid environments.

There is substantial evidence from psychology and medicine that pets are associated with better health and higher life satisfaction of their human companions. Yet whether this relationship is causal or purely a correlation remains largely unknown. We use an instrumental variable approach to overcome this, specifically exploiting relationships in which neighbours ask individuals to look over their property when traveling, which is correlated with pet companionship. We control for baseline relationships with neighbours as well as various other potential sources of bias. Using the Innovation Panel as part of the UK Household Longitudinal Survey, we find that a pet companion increases life satisfaction by 3 to 4 points on a scale of 1 to 7. Moreover, we estimate the size of the impact of pets on human life satisfaction and wellbeing in monetary units. We find that having a pet companion is worth up to £70,000 a year in terms of life satisfaction, similar to values obtained in the literature for meeting with friends and relatives on a regular basis.

Dog owners often ascribe human qualities to their dogs and, as such, view them as close others and a source of need support that fosters psychological well-being—this is called the pet effect. In this work, we went beyond the effect of what owners receive from their dogs and examined the benefits of giving need support. Applying self-determination theory’s conceptualization of basic psychological needs for autonomy, relatedness, and competence, we designed a 21-daily diary study (n = 104). Results showed giving need support to a dog contributed to owners’ well-being, lessened their psychological distress, and led to greater closeness to the dog, beyond the contribution of receiving need support. Similar to previous research, we observed benefits for receiving need support. In addition, well-being and closeness increased the tendency to care for a dog. These results support the notion that giving daily need support to a close other, a dog in this case, is beneficial to psychological wellness.

Companion animals have been identified as a unique source of social support and as contributors to mental wellbeing. This study uses the Experience Sampling Method to test whether this effect is due to stress-buffering. A total of 159 dog and cat owners responded to a series of randomly scheduled questionnaires on their smartphones. At each measurement moment, they reported in whether a pet is present at that moment and to what extent they have interacted with the pet. They also reported on stressful activities and events and on their current positive (PA) and negative (NA) affect. Multilevel regression analyses showed that when a companion animal was present (vs. absent) the negative association between stress and PA is less pronounced (event stress: B = 0.13, p = 0.002, 95% CI = 0.05; 0.21 activity stress: B = 0.08, p < 0.001, 95% CI = 0.04; 0.12). No additional main effect was revealed when tested in a subsample of records that reported low or no stress. Main effects were found for the presence of a companion animal on negative affect (B = 0.08, p < 0.001; 95% CI = 0.12; 0.05) and for interacting with a companion animal on positive affect (B = 0.06, p < 0.001; 95% CI = 0.04; 0.08). This shows that the presence of a companion animal buffers against the negative consequences of stress on positive affect, indicating stress-buffering as a mechanism behind the pet-effect. It is, however, not the only mechanism and more research is required to further elucidate how companion animals contribute to human wellbeing.

Pet dogs, therapy dogs, and service dogs can be seen in workplaces with increasing frequency. Although dogs may provide many benefits to employees and employers, their presence may introduce additional hazards and concerns to the work environment. Therefore, decisions to accept dogs in the workplace may include many considerations including the health, safety, and well-being of employees, legal and cultural sensitivities, and animal welfare. The present paper serves to introduce the issue of dogs in the workplace and outline the potential benefits and challenges to their presence. The legal accommodations afforded to certain types of dogs in workplace settings are discussed, and the research findings pertaining to the potential benefits of dogs on human health and well-being are summarized. The paper concludes with considerations for human resource management personnel in the areas of diversity, employee relations, ethics and corporate responsibility, organizational and employee development, safety and security, and legal considerations, as well as suggested topics for future research.

Studies in the field of human–animal interaction tend to highlight the positive results of the influence of animals on humans, which supports the popular belief that the human–animal bond positively affects humans’ well-being (“pet-effect”). Nevertheless, contradictory results exist that seem especially visible since the COVID-19 pandemic, a prominent external stressor. Despite critical findings, individuals seem to want to believe in the beneficial effects of the human–animal relationship (“pet-effect paradox”). Based on this background, the present study aims to investigate this phenomenon using a mixed-method design. Therefore, animal caregivers were surveyed online and compared using psychometric measurements and open-ended questions. In this context, a special focus was placed on the additional stressor of Long-Covid and related concerns. The results demonstrate once more the existence of the “pet-effect paradox” due to a contradiction in the quantitative and qualitative results. At a quantitative level, the findings show additional burdens on animal caregivers who are confronted with multiple loads. However, the qualitative results indicate a belief in the beneficial effects of pets at the biopsychosocial level. Additionally, the data demonstrate a shift in focus away from the environment to oneself when affected by Long-Covid, which might affect the ability to care for an animal.

Compatibility in activity preferences refers to the shared enjoyment of daily activities, such as walking and interacting with others, and it is an indicator of the behavioral dimension of compatibility, which mainly refers to exercise and play. It has been found that individuals who are more compatible with their dogs have a better relationship with them, which can explain some of the benefits of human-dog interaction. However, research to explain how and why human-animal relationships are potentially therapeutic is still needed. The objective of this quantitative study was to compare the benefits of human-dog interaction for both humans and dogs between people who were and were not compatible with their dogs. Ninety people with scores of 50% or less on the compatibility index and 110 people with 100% compatibility participated in the study. The groups were compared using the Mann-Whitney U test. The people in the group with greater compatibility reported more subjective happiness and less perceived stress, a stable dog-feeding routine, and more frequent daily walks and playing sessions; additionally, for their dogs, they reported a lower frequency of aggressive and fearful behaviors and higher trainability scores. In conclusion, compatibility in activity preferences helps explain the benefits of human–animal interaction.

A pharmacologist and a veterinarian pull back the curtain on the human and animal health effects of hydraulic fracturing, or ';fracking' Across the country, frackingthe extraction of natural gas by hydraulic fracturingis being touted as the nation's answer to energy independence and a fix for a flagging economy. Drilling companies assure us that the process is safe, politicians push through drilling legislation without a serious public-health debate, and those who speak out are marginalized, their silence purchased by gas companies and their warnings about the dangers of fracking stifled. The Real Cost of Fracking pulls back the curtain on how this toxic process endangers the environment and harms people, pets, and livestock. Michelle Bamberger, a veterinarian, and Robert Oswald, a pharmacologist, combine their expertise to show how contamination at drilling sites translates into ill health and heartbreak for families and their animals. By giving voice to the people at ground zero of the fracking debate, the authors vividly illustrate the consequences of fracking and issue an urgent warning to all of us: fracking poses a dire threat to the air we breathe, the water we drink, and even our food supply. Bamberger and Oswald reveal the harrowing experiences of small farmers who have lost their animals, their livelihoods, and their peace of mind, and of rural families whose property values have plummeted as their towns have been invaded by drillers. At the same time, these stories give us hope, as people band together to help one another and courageously fight to reclaim their communities. The debate over fracking speaks to a core dilemma of contemporary life: we require energy to live with modern conveniences, but what degree of environmental degradation, health risks, and threats to our food supply are we willing to accept to obtain that energy? As these stories demonstrate, the stakes couldn't be higher, and this is an issue that none of us can afford to ignore.From the Hardcover edition.

Whether they see themselves as King of the Wild Things or protector of Toto, children live in a world filled with animals--both real and imaginary.From Black Beauty to Barney, animal characters romp through children's books, cartoons, videos, and computer games.