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Overview of the Development of Planar Motor Technology
2024
With the rapid development of the semiconductor chip and precision machining industry, there is a growing demand for high-performance planar drive devices, leading to an increasing depth of research on planar motors. Variable reluctance planar motors, induction planar motors, permanent-magnet synchronous planar motors and DC planar motors are discussed in this paper along with their working principles and current research status. The theory of planar motors remains incomplete and immature despite the extensive research conducted by scholars and research institutions on crucial aspects like magnetic field analysis and electromagnetic force calculations. The objective of this paper is to provide a comprehensive review of the research and development status of planar motors in order to positively impact future advancements in this field.
Journal Article
Self-feeding MUSE: A robust method for high resolution diffusion imaging using interleaved EPI
2015
Single-shot echo planar imaging (EPI) with parallel imaging techniques has been well established as the most popular method for clinical diffusion imaging, due to its fast acquisition and motion insensitivity. However, this approach is limited by the relatively low spatial resolution and image distortion. Interleaved EPI is able to break the limitations but the phase variations among different shots must be considered for artifact suppression. The introduction of multiplexed sensitivity-encoding (MUSE) can address the phase issue using sensitivity encoding (SENSE) for self-navigation of each interleave. However, MUSE has suboptimal results when the number of shots is high. To achieve higher spatial resolution and lower geometric distortion, we introduce two new schemes into the MUSE framework: 1) a self-feeding mechanism is adopted by using prior information regularized SENSE in order to obtain reliable phase estimation; and 2) retrospective motion detection and data rejection strategies are performed to exclude unusable data corrupted by severe pulsatile motions. The proposed method is named self-feeding MUSE (SF-MUSE). Experiments on healthy volunteers demonstrate that this new SF-MUSE approach provides more accurate motion-induced phase estimation and fewer artifacts caused by data corruption when compared with the original MUSE method. SF-MUSE is a robust method for high resolution diffusion imaging and suitable for practical applications with reasonable scan time.
•More accurate phase variation estimation•Corrupt data detection and rejection for motion artifact suppression•Navigator-free and thus high acquisition efficiency•Better image quality with reduced artifacts than the conventional MUSE approach
Journal Article
Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial
by
Schultz, David
,
Davis, Stephen M
,
De Silva, Deidre A
in
Aged
,
Aged, 80 and over
,
Double-Blind Method
2008
Whether intravenous tissue plasminogen activator (alteplase) is effective beyond 3 h after onset of acute ischaemic stroke is unclear. We aimed to test whether alteplase given 3–6 h after stroke onset promotes reperfusion and attenuates infarct growth in patients who have a mismatch in perfusion-weighted MRI (PWI) and diffusion-weighted MRI (DWI).
We prospectively and randomly assigned 101 patients to receive alteplase or placebo 3–6 h after onset of ischaemic stroke. PWI and DWI were done before and 3–5 days after therapy, with T2-weighted MRI at around day 90. The primary endpoint was infarct growth between baseline DWI and the day 90 T2 lesion in mismatch patients. Major secondary endpoints were reperfusion, good neurological outcome, and good functional outcome. Patients, caregivers, and investigators were unaware of treatment allocations. Primary analysis was per protocol. This study is registered with
ClinicalTrials.gov, number
NCT00238537.
We randomly assigned 52 patients to alteplase and 49 patients to placebo. Mean age was 71·6 years, and median score on the National Institutes of Health stroke scale was 13. 85 of 99 (86%) patients had mismatch of PWI and DWI. The geometric mean infarct growth (exponential of the mean log of relative growth) was 1·24 with alteplase and 1·78 with placebo (ratio 0·69, 95% CI 0·38–1·28; Student's
t test p=0·239); the median relative infarct growth was 1·18 with alteplase and 1·79 with placebo (ratio 0·66, 0·36–0·92; Wilcoxon's test p=0·054). Reperfusion was more common with alteplase than with placebo and was associated with less infarct growth (p=0·001), better neurological outcome (p<0·0001), and better functional outcome (p=0·010) than was no reperfusion.
Alteplase was non-significantly associated with lower infarct growth and significantly associated with increased reperfusion in patients who had mismatch. Because reperfusion was associated with improved clinical outcomes, phase III trials beyond 3 h after treatment are warranted.
National Health and Medical Research Council, Australia; National Stroke Foundation, Australia; Heart Foundation of Australia.
Journal Article
A robust multi-shot scan strategy for high-resolution diffusion weighted MRI enabled by multiplexed sensitivity-encoding (MUSE)
by
Guidon, Arnaud
,
Chang, Hing-Chiu
,
Chen, Nan-kuei
in
Biological and medical sciences
,
Diffusion weighted imaging
,
Fundamental and applied biological sciences. Psychology
2013
Diffusion weighted magnetic resonance imaging (DWI) data have been mostly acquired with single-shot echo-planar imaging (EPI) to minimize motion induced artifacts. The spatial resolution, however, is inherently limited in single-shot EPI, even when the parallel imaging (usually at an acceleration factor of 2) is incorporated. Multi-shot acquisition strategies could potentially achieve higher spatial resolution and fidelity, but they are generally susceptible to motion-induced phase errors among excitations that are exacerbated by diffusion sensitizing gradients, rendering the reconstructed images unusable. It has been shown that shot-to-shot phase variations may be corrected using navigator echoes, but at the cost of imaging throughput. To address these challenges, a novel and robust multi-shot DWI technique, termed multiplexed sensitivity-encoding (MUSE), is developed here to reliably and inherently correct nonlinear shot-to-shot phase variations without the use of navigator echoes. The performance of the MUSE technique is confirmed experimentally in healthy adult volunteers on 3Tesla MRI systems. This newly developed technique should prove highly valuable for mapping brain structures and connectivities at high spatial resolution for neuroscience studies.
► Our multi-shot EPI reconstruction strategy enables DWI of high spatial-resolution. ► Motion-induced phase errors can be removed inherently with a novel MUSE algorithm. ► The new algorithm produces data with higher SNR than conventional parallel imaging.
Journal Article
Arbitrary spin-to–orbital angular momentum conversion of light
by
Ambrosio, Antonio
,
Mueller, J. P. Balthasar
,
Rubin, Noah A.
in
Angular momentum
,
Atmospheric pressure
,
Electron beams
2017
Optical elements that convert the spin angular momentum (SAM) of light into vortex beams have found applications in classical and quantum optics. These elements—SAM-to–orbital angular momentum (OAM) converters—are based on the geometric phase and only permit the conversion of left- and right-circular polarizations (spin states) into states with opposite OAM. We present a method for converting arbitrary SAM states into total angular momentum states characterized by a superposition of independent OAM. We designed a metasurface that converts left- and right-circular polarizations into states with independent values of OAM and designed another device that performs this operation for elliptically polarized states. These results illustrate a general material-mediated connection between SAM and OAM of light and may find applications in producing complex structured light and in optical communication.
Journal Article
Assessing methods for geometric distortion compensation in 7 T gradient echo functional MRI data
2021
Echo planar imaging (EPI) is widely used in functional and diffusion‐weighted MRI, but suffers from significant geometric distortions in the phase encoding direction caused by inhomogeneities in the static magnetic field (B0). This is a particular challenge for EPI at very high field (≥7 T), as distortion increases with higher field strength. A number of techniques for distortion correction exist, including those based on B0 field mapping and acquiring EPI scans with opposite phase encoding directions. However, few quantitative comparisons of distortion compensation methods have been performed using human EPI data, especially at very high field. Here, we compared distortion compensation using B0 field maps and opposite phase encoding scans in two different software packages (FSL and AFNI) applied to 7 T gradient echo (GE) EPI data from 31 human participants. We assessed distortion compensation quality by quantifying alignment to anatomical reference scans using Dice coefficients and mutual information. Performance between FSL and AFNI was equivalent. In our whole‐brain analyses, we found superior distortion compensation using GE scans with opposite phase encoding directions, versus B0 field maps or spin echo (SE) opposite phase encoding scans. However, SE performed better when analyses were limited to ventromedial prefrontal cortex, a region with substantial dropout. Matching the type of opposite phase encoding scans to the EPI data being corrected (e.g., SE‐to‐SE) also yielded better distortion correction. While the ideal distortion compensation approach likely varies depending on methodological differences across experiments, this study provides a framework for quantitative comparison of different distortion compensation methods. We compared distortion compensation using B0 field maps and opposite phase encoding scans in two different software packages (FSL and AFNI) applied to 7 T gradient echo (GE) echo planar imaging data from 31 human participants. We assessed distortion compensation quality by quantifying alignment to anatomical reference scans using Dice coefficients and mutual information. In our whole‐brain analyses, we found superior distortion compensation using GE scans with opposite phase encoding directions, versus B0 field maps or spin echo opposite phase encoding scans.
Journal Article
Dynamic multi-coil technique (DYNAMITE) shimming for echo-planar imaging of the human brain at 7 Tesla
by
Nixon, Terence W.
,
Juchem, Christoph
,
Umesh Rudrapatna, S.
in
Acquisitions & mergers
,
Adult
,
Brain
2015
Gradient-echo echo-planar imaging (EPI) is the primary method of choice in functional MRI and other methods relying on fast MRI to image brain activation and connectivity. However, the high susceptibility of EPI towards B0 magnetic field inhomogeneity poses serious challenges. Conventional magnetic field shimming with low-order spherical harmonic (SH) functions is capable of compensating shallow field distortions, but performs poorly for global brain shimming or on specific areas with strong susceptibility-induced B0 distortions such as the prefrontal cortex (PFC). Excellent B0 homogeneity has been demonstrated recently in the human brain at 7 Tesla with the DYNAmic Multi-coIl TEchnique (DYNAMITE) for magnetic field shimming (J Magn Reson (2011) 212:280–288). Here, we report the benefits of DYNAMITE shimming for multi-slice EPI and T2* mapping.
A standard deviation of 13Hz was achieved for the residual B0 distribution in the human brain at 7 Tesla with DYNAMITE shimming and was 60% lower compared to conventional shimming that employs static zero through third order SH shapes. The residual field inhomogeneity with SH shimming led to an average 8mm shift at acquisition parameters commonly used for fMRI and was reduced to 1.5-3mm with DYNAMITE shimming. T2* values obtained from the prefrontal and temporal cortices with DYNAMITE shimming were 10-50% longer than those measured with SH shimming. The reduction of the confounding macroscopic B0 field gradients with DYNAMITE shimming thereby promises improved access to the relevant microscopic T2* effects.
The combination of high spatial resolution and DYNAMITE shimming allows largely artifact-free EPI and T2* mapping throughout the brain, including prefrontal and temporal lobe areas. DYNAMITE shimming is expected to critically benefit a wide range of MRI applications that rely on excellent B0 magnetic field conditions including EPI-based fMRI to study various cognitive processes and assessing large-scale brain connectivity in vivo. As such, DYNAMITE shimming has the potential to replace conventional SH shim systems in human MR scanners.
[Display omitted]
•DYNAMITE shimming provides high level B0 homogeneity throughout the human brain.•DYNAMITE shimming outperforms conventional spherical harmonics shimming.•Signal dropout and pixel misregistration of echo-planar imaging (EPI) are minimized.•Removal of macroscopic field gradients improves mapping of microscopic T2* effects.•DYNAMITE shimming is expected to benefit a wide range of brain MRI applications.
Journal Article
Accelerating acquisition of readout-segmented echo planar imaging with a simultaneous multi-slice (SMS) technique for diagnosing breast lesions
by
Liu, Wei
,
Hu, Yiqi
,
Zhang, Xiaoyong
in
Breast
,
Breast cancer
,
Breast Neoplasms - diagnostic imaging
2021
Objectives
To investigate the feasibility and effectiveness of SMS rs-EPI for evaluating breast lesions.
Methods
This prospective study was approved by IRB. Ninety-six patients had 102 histopathologically verified lesions (80 malignant and 22 benign) that were evaluated. Conventional rs-EPI and SMS rs-EPI data were acquired on a 3T scanner. Mean kurtosis (MK), mean diffusion (MD), and apparent diffusion coefficient (ADC) values were quantitatively calculated for each lesion on both sequences. Images were qualitatively and quantitatively analyzed with respect to image sharpness, geometric distortion, lesion conspicuity, anatomic structure, overall image quality, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR). Student’s
t
test, Pearson correlation, receiver operating characteristic curve, Wilcoxon rank sum test, and paired-sample
t
tests were used for statistical analysis.
Results
Compared to conventional rs-EPI, the acquisition time of SMS rs-EPI was markedly reduced (2:17 min vs 4:27 min). Pearson’s correlations showed excellent linear relationships for each parameter between conventional rs-EPI and SMS rs-EPI (MK,
r
= 0.908; MD,
r
= 0.938; and ADC,
r
= 0.975;
p
< 0.01 for all). Furthermore, SMS rs-EPI had similar diagnostic performance compared with conventional rs-EPI. SMS rs-EPI had comparable visual image quality as conventional rs-EPI, with excellent inter-reader reliability (ICC = 0.851–0.940). No differences existed between conventional rs-EPI and SMS rs-EPI for either SNR or CNR (
p
> 0.05).
Conclusions
Applying the SMS technique can significantly reduce the acquisition time and produce similar diagnostic accuracy while generating comparable image quality as the conventional rs-EPI.
Key Points
• SMS rs-EPI reduces scan time from 4:27 min to 2:17 min compared with conventional rs-EPI.
• SMS rs-EPI has a comparable diagnostic performance to conventional rs-EPI in the differentiation between malignant and benign breast lesions.
• SMS rs-EPI demonstrates comparable image quality to conventional rs-EPI with shorter scan time.
Journal Article
High-fidelity mesoscale in-vivo diffusion MRI through gSlider-BUDA and circular EPI with S-LORAKS reconstruction
by
Tian, Qiyuan
,
Yarach, Uten
,
Cao, Xiaozhi
in
Brain - diagnostic imaging
,
Computer Simulation
,
Diffusion Magnetic Resonance Imaging - methods
2023
•We developed complementary 2D partial Fourier and circular-BUDA-EPI to achieve high-resolution diffusion MRI with reduced TE.•We utilized phase constrained low-rank reconstruction to account for phase variations and enable high-fidelity partial Fourier filling.•We demonstrated the effectiveness of our proposed method by producing high-fidelity diffusion MRI with 500 µm-isotropic resolution.
To develop a high-fidelity diffusion MRI acquisition and reconstruction framework with reduced echo-train-length for less T2* image blurring compared to typical highly accelerated echo-planar imaging (EPI) acquisitions at sub-millimeter isotropic resolution.
We first proposed a circular-EPI trajectory with partial Fourier sampling on both the readout and phase-encoding directions to minimize the echo-train-length and echo time. We then utilized this trajectory in an interleaved two-shot EPI acquisition with reversed phase-encoding polarity, to aid in the correction of off-resonance-induced image distortions and provide complementary k-space coverage in the missing partial Fourier regions. Using model-based reconstruction with structured low-rank constraint and smooth phase prior, we corrected the shot-to-shot phase variations across the two shots and recover the missing k-space data. Finally, we combined the proposed acquisition/reconstruction framework with an SNR-efficient RF-encoded simultaneous multi-slab technique, termed gSlider, to achieve high-fidelity 720 µm and 500 µm isotropic resolution in-vivo diffusion MRI.
Both simulation and in-vivo results demonstrate the effectiveness of the proposed acquisition and reconstruction framework to provide distortion-corrected diffusion imaging at the mesoscale with markedly reduced T2*-blurring. The in-vivo results of 720 µm and 500 µm datasets show high-fidelity diffusion images with reduced image blurring and echo time using the proposed approaches.
The proposed method provides high-quality distortion-corrected diffusion-weighted images with ∼40% reduction in the echo-train-length and T2* blurring at 500µm-isotropic-resolution compared to standard multi-shot EPI.
Journal Article
Optical Sensors for Multi-Axis Angle and Displacement Measurement Using Grating Reflectors
2019
In dimensional metrology it is necessary to carry out multi-axis angle and displacement measurement for high-precision positioning. Although the state-of-the-art linear displacement sensors have sub-nanometric measurement resolution, it is not easy to suppress the increase of measurement uncertainty when being applied for multi-axis angle and displacement measurement due to the Abbe errors and the influences of sensor misalignment. In this review article, the state-of-the-art multi-axis optical sensors, such as the three-axis autocollimator, the three-axis planar encoder, and the six-degree-of-freedom planar encoder based on a planar scale grating are introduced. With the employment of grating reflectors, measurement of multi-axis translational and angular displacement can be carried out while employing a single laser beam. Fabrication methods of a large-area planar scale grating based on a single-point diamond cutting with the fast tool servo technique and the interference lithography are also presented, followed by the description of the evaluation method of the large-area planar scale grating based on the Fizeau interferometer.
Journal Article