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A complete illustrated history of one of the most popular rock bands of all time, Pink Floyd. With more than 250 images and a complete discography.

This book reveals the Conservative Party’s relationship with the extreme right between 1945 and 1975. For the first time, this book shows how the Conservative Party, realising that its well known pre-Second World War connections with the extreme right were now embarrassing, used its bureaucracy to implement a policy of investigating extreme right groups and taking action to minimise their chances of success.The book focuses on the Conservative Party’s investigation of right-wing groups, and shows how its perception of their nature determined the party bureaucracy’s response. The book draws a comparison between the Conservative Party machine’s negative attitude towards the extreme right and its support for progressive groups. It concludes that the Conservative Party acted as a persistent block to the external extreme right in a number of ways, and that the Party bureaucracy persistently denied the extreme right within the party assistance, access to funds, and representation within party organisations. It reaches a climax with the formulation of ‘plan’ threatening its own candidate if he failed to remove the extreme right from the Conservative Monday Club.

This book reveals the Conservative Party's relationship with the extreme right between 1945 and 1975. Commentators frequently cite the relationship between the Conservative Party and the extreme right. For the first time, this book shows how the Conservative Party, realising that its wel-documented pre-Second World War connections with the extreme right were now embarrassing, used its bureaucracy to implement a policy of investigating extreme right groups and taking action to minimise their chances of success. The book focuses on the Conservative Party's investigation of right-wing groups, and shows how its perception of their nature determined the party bureaucracy's response. It draws on extensive information from the Conservative Party Archive, supported by other sources, including interviews with leading players in the events of the 1970s. The book draws a comparison between the Conservative Party machine's negative attitude towards the extreme right and its support for progressive groups. It concludes that the Conservative Party acted as a persistent block to the external extreme right in a number of ways, and that the Party bureaucracy persistently denied the extreme right within the party assistance, access to funds, and representation within party organisations. It reaches a climax with the formulation of a 'plan' threatening its own candidate if he failed to remove the extreme right from the Conservative Monday Club. This book examines a topic that is of enduring interest. It will appeal to students and enthusiasts alike, and become a standard textbook for undergraduates and postgraduates. Summary reprinted by permission of Manchester University Press

The self-to-other model of empathy (SOME) states that a key reason for the empathic deficiency in autistic individuals is the imbalance of the self–other switch. The existing interventions of theory of mind contain training of self–other transposition ability but combined with other cognitive trainings. The self–other distinction brain areas of autistic individuals have been revealed, but the brain areas of the self–other transposition ability and its intervention have not been investigated. There are normalized amplitudes of low-frequency fluctuations (mALFFs) within 0.01–0.1 Hz and many normalized amplitudes of frequency fluctuations (mAFFs) within 0–0.01, 0.01–0.05, 0.05–0.1, 0.1–0.15, 0.15–0.2, and 0.2–0.25 Hz. Therefore, the current study established a progressive self–other transposition group intervention to specifically and systematically improve autistic children’s self–other transposition abilities. The transposition test with a three mountains test, an unexpected location test, and a deception test was used to directly measure autistic children’s transposition abilities. The Interpersonal Responsiveness Index Empathy Questionnaire with perspective-taking and fantasy subscales (IRI-T) was used to indirectly measure autistic children’s transposition abilities. The Autism Treatment Evaluation Checklist (ATEC) was used to measure autistic children’s autism symptoms. The experiment was designed with two (intervention: experimental group vs. control group) independent variables and two (test time: pretest vs. posttest or tracking test) × three (test: transposition test vs. IRI-T test vs. ATEC test) dependent variables. Furthermore, it used eyes-closed resting-state functional magnetic resonance imaging to investigate and compare the relevant maternal mALFFs and average energy rank and energy rank variability of mAFFs of autistic children’s transposition abilities, autism symptoms, and intervention effects. The results showed the following: (1) There were many improvements (pretest vs. posttest or tracking test) greater than chance 0 in the experimental group, such as the three mountains, lie, transposition, PT, IRI-T, PT tracking, cognition, behavior, ATEC, language tracking, cognition tracking, behavior tracking, and ATEC tracking improvements. However, there was no improvement greater than chance 0 in the control group. (2) The maternal mALFFs and maternal average energy rank and energy rank variability of mAFFs could predict the autistic children’s transposition abilities, autism symptoms, and intervention effects with some overlap and some difference in maternal self–other distinction, sensorimotor, visual, facial expression recognition, language, memory and emotion, and self-consciousness networks. These results indicated that the progressive self–other transposition group intervention successfully improved autistic children’s transposition abilities and reduced their autism symptoms; the intervention effects could be applied to daily life and last up to a month. The maternal mALFFs, average energy rank, and energy rank variability of mAFFs were three effective neural indictors of autistic children’s transposition abilities, autism symptoms, and intervention effects, and the average energy rank and energy rank variability of mAFFs were two new neural indictors established in the current study. The maternal neural markers of the progressive self–other transposition group intervention effects for autistic children were found in part.

This chapter contains sections titled: References

This chapter focuses on the rise of left caucuses and their battle with the New York City Teachers Union's (TU) social democratic leadership. Communist control of the TU can be traced to the battles of the American left, especially the early schism between the Communist Party of the United States of America (CPUSA) and those associated with Jay Lovestone's American Communist Opposition (ACO) in 1929. The conflict between ACO and CPUSA would lead to the formation of the two major caucuses in the TU: the Rank and File, affiliated with the Communist Party, and the Progressive Group, made up of followers of Lovestone and the ACO. The chapter examines the ideological divide between the Communist caucuses and the TU leadership, Henry Linville and Abraham Lefkowitz's unsuccessful attempt to remove the Communists from the union, the 1935 schism, and the formation of the Teachers Guild. After the 1935 walkout of Linville, Lefkowitz, and 700 members of the TU, the Communists gained control of the union.

Throughout Bermuda’s 400-year history, power in Bermuda has been tightly vested in the island’s White elite. Through piracy, racketeering, and the enslavement of African people, these “Forty Thieves” generated an insurmountable quantity of eco-political power that allowed them to continue to dominate the island’s Black majority well after the abolition of chattel slavery. A 1834 Voting Act was one of the most crippling methods employed by Whites to maintain political control of the island well into the twentieth century. It was based on a dramatic increase of already rigid property qualifications for participation in civil matters such as voting, serving on juries, and standing for elections.1

A randomized, double-blind, placebo-controlled, 52-week study (no. NCT03068468) evaluated gosuranemab, an anti-tau monoclonal antibody, in the treatment of progressive supranuclear palsy (PSP). In total, 486 participants dosed were assigned to either gosuranemab ( n  = 321) or placebo ( n  = 165). Efficacy was not demonstrated on adjusted mean change of PSP Rating Scale score at week 52 between gosuranemab and placebo (10.4 versus 10.6, P  = 0.85, primary endpoint), or at secondary endpoints, resulting in discontinuation of the open-label, long-term extension. Unbound N-terminal tau in cerebrospinal fluid decreased by 98% with gosuranemab and increased by 11% with placebo ( P  < 0.0001). Incidences of adverse events and deaths were similar between groups. This well-powered study suggests that N-terminal tau neutralization does not translate into clinical efficacy. In the phase 2 PASSPORT study, treatment with the anti-tau antibody gosuranemab did not show clinical benefit in participants with supranuclear palsy, suggesting that N-terminal tau neutralization does not translate into clinical efficacy.

Background Fatigue is a common and troubling symptom for people with multiple sclerosis (MS). Aim To evaluate the effectiveness and cost-effectiveness of a six-session group-based programme for managing MS-fatigue (Fatigue: Applying Cognitive behavioural and Energy effectiveness Techniques to lifeStyle (FACETS)). Methods Three-centre parallel arm randomised controlled trial with economic evaluation. Patients with MS and significant fatigue were randomised to FACETS plus current local practice (FACETS) or current local practice alone (CLP), using concealed computer-generated randomisation. Participant blinding was not possible. Primary outcomes were fatigue severity (Fatigue Assessment Instrument), self-efficacy (Multiple Sclerosis-Fatigue Self-Efficacy) and disease-specific quality of life (Multiple Sclerosis Impact Scale (MSIS-29)) at 1 and 4 months postintervention (follow-up 1 and 2). Quality adjusted life years (QALYs) were calculated (EuroQoL 5-Dimensions questionnaire and the Short-form 6-Dimensions questionnaire). Results Between May 2008 and November 2009, 164 patients were randomised; primary outcome data were available for 146 (89%). Statistically significant differences favour the intervention group on fatigue self-efficacy at follow-up 1 (mean difference (MD) 9, 95% CI (4 to 14), standardised effect size (SES) 0.54, p=0.001) and follow-up 2 (MD 6, 95% CI (0 to 12), SES 0.36, p=0.05) and fatigue severity at follow-up 2 (MD −0.36, 95% CI (−0.63 to −0.08), SES −0.35, p=0.01) but no differences for MSIS-29 or QALYs. No adverse events reported. Estimated cost per person for FACETS is £453; findings suggest an incremental cost-effectiveness ratio of £2157 per additional person with a clinically significant improvement in fatigue. Conclusions FACETS is effective in reducing fatigue severity and increasing fatigue self-efficacy. However, it is difficult to assess the additional cost in terms of cost-effectiveness (ie, cost per QALY) as improvements in fatigue are not reflected in the QALY outcomes, with no significant differences between FACETS and CLP. The strengths of this trial are its pragmatic nature and high external validity. Trial registration: Current Controlled Trials ISRCTN76517470.