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368,663 result(s) for "tomography"
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Implant Restorations
The fourth edition of Implant Restorations: A Step-by-Step Guide provides a wealth of updated and expanded coverage on detailed procedures for restoring dental implants. Focusing on the most common treatment scenarios, it offers concise literature reviews for each chapter and easy-to-follow descriptions of the techniques, along with high-quality clinical photographs demonstrating each step. Comprehensive throughout, this practical guide begins with introductory information on incorporating implant restorative dentistry in clinical practice. It covers diagnosis and treatment planning and digital dentistry, and addresses advances in cone beam computerized tomography (CBCT), treatment planning software, computer generated surgical guides, rapid prototype printing and impression-less implant restorative treatments, intra-oral scanning, laser sintering, and printing/milling polymer materials. Record-keeping, patient compliance, hygiene regimes, and follow-up are also covered. * Provides an accessible step-by-step guide to commonly encountered treatment scenarios, describing procedures and techniques in an easy-to-follow, highly illustrated format * Offers new chapters on diagnosis and treatment planning and digital dentistry * Covers advances in cone beam computerized tomography (CBCT), computer generated surgical guides, intra-oral scanning, laser sintering, and more An excellent and accessible guide on a burgeoning subject in modern dental practice by one of its most experienced clinicians, Implant Restorations: A Step-by-Step Guide, Fourth Edition will appeal to prosthodontists, general dentists, implant surgeons, dental students, dental assistants, hygienists, and dental laboratory technicians.
5 Impact of preprocedural computer tomography versus transoesophageal echocardiography for left atrial appendage occlusion procedure planning
BackgroundThe left atrial appendage (LAA) is the central anatomical structure implicated in the pathogenesis of nonvalvular atrial fibrillation related strokes. Where long-term oral anticoagulation is contraindicated, percutaneous transcatheter left atrial appendage occlusion (LAAO) may be considered. Due to wide variation in LAA anatomy, preprocedural imaging is a key step for procedure planning. While transoesophageal echocardiography (TOE) remains the gold standard for procedure planning, high quality 3-dimensional images from cardiac computer tomography (CT) may provide more accurate sizing parameters, resulting in improvements to device selection and procedural efficiency. We compare the outcomes of preprocedural CT versus TOE for LAAO procedure planning.MethodsA single-centre retrospective cohort study of all LAAO procedures was performed. Patients received either preprocedural CT or TOE and were divided into CT or TOE group respectively. The primary outcome was procedure success and major adverse event rate. The secondary outcome was total procedure time, rate of device size change, and LAA sizing parameters.Results64 patients underwent LAAO in our centre. 39 (60.9%) and 25 (39.1%) had preprocedural CT and TOE respectively. There was no statistically significant difference in procedure success rate (100% vs 96.0%, P = 0.39) and major adverse event rate (5.1% vs 4.0%, P = 1.00) when CT was compared to TOE (table 1). Preprocedural CT was associated with significantly shorter total procedure time (mean, 104.6 minutes vs 139.6 minutes, P = 0.009) and lower rate of device size change (7.7% vs 28.0%, P = 0.039) when compared to TOE (table 2). The percentage device oversizing from measured landing zone was significantly lower in the CT group when compared to TOE (mean, 12.6% vs 18.6%, P = 0.02), suggesting CT parameters correlated more closely to anatomical dimensions. Preprocedural TOE was associated with significantly lower measured maximum landing zone diameter (mean, 20.8 mm vs 25.8 mm, P < 0.001) and higher rate of device upsizing (24.0% vs 2.6%, P = 0.01) when compared to CT.Abstract 5 Table 1Baseline patient characteristicsAbstract 5 Table 2Procedure outcomes, characteristics and left atrial appendage characteristicsConclusionLAAO preprocedural CT is associated with shorter total procedure time, lower rate of device size change, and is less likely to underestimate LAA sizing parameters when compared to preprocedural TOE.
Exposure to low dose computed tomography for lung cancer screening and risk of cancer: secondary analysis of trial data and risk-benefit analysis
Objective To estimate the cumulative radiation exposure and lifetime attributable risk of cancer incidence associated with lung cancer screening using annual low dose computed tomography (CT).Design Secondary analysis of data from a lung cancer screening trial and risk-benefit analysis.Setting 10 year, non-randomised, single centre, low dose CT, lung cancer screening trial (COSMOS study) which took place in Milan, Italy in 2004-15 (enrolment in 2004-05). Secondary analysis took place in 2015-16.Participants High risk asymptomatic smokers aged 50 and older, who were current or former smokers (≥20 pack years), and had no history of cancer in the previous five years.Main outcome measures Cumulative radiation exposure from low dose CT and positron emission tomography (PET) CT scans, calculated by dosimetry software; and lifetime attributable risk of cancer incidence, calculated from the Biological Effects of Ionizing Radiation VII (BEIR VII) report.Results Over 10 years, 5203 participants (3439 men, 1764 women) underwent 42 228 low dose CT and 635 PET CT scans. The median cumulative effective dose at the 10th year of screening was 9.3 mSv for men and 13.0 mSv for women. According to participants’ age and sex, the lifetime attributable risk of lung cancer and major cancers after 10 years of CT screening ranged from 5.5 to 1.4 per 10 000 people screened, and from 8.1 to 2.6 per 10 000 people screened, respectively. In women aged 50-54, the lifetime attributable risk of lung cancer and major cancers was about fourfold and threefold higher than for men aged 65 and older, respectively. The numbers of lung cancer and major cancer cases induced by 10 years of screening in our cohort were 1.5 and 2.4, respectively, which corresponded to an additional risk of induced major cancers of 0.05% (2.4/5203). 259 lung cancers were diagnosed in 10 years of screening; one radiation induced major cancer would be expected for every 108 (259/2.4) lung cancers detected through screening.Conclusion Radiation exposure and cancer risk from low dose CT screening for lung cancer, even if non-negligible, can be considered acceptable in light of the substantial mortality reduction associated with screening.
18FFDG PET/CT performs better than CT in determining the bone biopsy site : randomized controlled clinical trial
Background Bone biopsy is the gold standard for diagnosing bone metastases. However, there is no clinical consensus regarding the optimal imaging test for determining the puncture site. Methods We compared the performance of [ 18 F]FDG PET/CT with CT in detecting bone metastases to achieve the highest biopsy efficiency. This registered prospective study enrolled 273 patients with bone lesions who were treated between January 2020 and March 2021. Patients were randomly assigned to undergo [ 18 F]FDG PET/CT or CT to determine the puncture site before bone biopsy. The accuracy, sensitivity, specificity, second biopsy rate, diagnostic time and cost-effectiveness of the two imaging tests were compared. Results The accuracy and sensitivity of [ 18 F]FDG PET/CT group in detecting bone metastases were significantly higher than CT group(97.08% vs. 90.44%, 98.76% vs. 92.22%, P  < 0.05). The second biopsy rate was significantly lower in the [ 18 F]FDG PET/CT group (2.19% vs. 5.15%; P  < 0.05). The diagnostic time of [ 18 F]FDG PET/CT was 18.33 ± 2.08 days, which was significantly shorter than 21.28 ± 1.25 days in CT group ( P  < 0.05). The cost of [ 18 F] FDG PETCT is 11428.35 yuan, and the cost of CT is 13287.52 yuan; the incremental cost is 1859.17 yuan. SUVmax > 6.3 combined with ALP > 103 U/L showed a tendency for tumor metastases with an AUC of 0.901 (95%CI 0.839 to 0.946, P  < 0.001). Conclusion [ 18 F]FDG PET/CT has better performance and cost-effectiveness than CT in determining the bone biopsy site for suspect bone metastases. Trial registration The prospective study was registered on 2018-04-10, and the registration number is ChiCTR1800015540.
Dual-Source Photon-Counting Computed Tomography—Part I: Clinical Overview of Cardiac CT and Coronary CT Angiography Applications
The photon-counting detector (PCD) is a new computed tomography detector technology (photon-counting computed tomography, PCCT) that provides substantial benefits for cardiac and coronary artery imaging. Compared with conventional CT, PCCT has multi-energy capability, increased spatial resolution and soft tissue contrast with near-null electronic noise, reduced radiation exposure, and optimization of the use of contrast agents. This new technology promises to overcome several limitations of traditional cardiac and coronary CT angiography (CCT/CCTA) including reduction in blooming artifacts in heavy calcified coronary plaques or beam-hardening artifacts in patients with coronary stents, and a more precise assessment of the degree of stenosis and plaque characteristic thanks to its better spatial resolution. Another potential application of PCCT is the use of a double-contrast agent to characterize myocardial tissue. In this current overview of the existing PCCT literature, we describe the strengths, limitations, recent applications, and promising developments of employing PCCT technology in CCT.
EANM procedure guidelines for brain PET imaging using 18FFDG, version 3
The present procedural guidelines summarize the current views of the EANM Neuro-Imaging Committee (NIC). The purpose of these guidelines is to assist nuclear medicine practitioners in making recommendations, performing, interpreting, and reporting results of [ 18 F]FDG-PET imaging of the brain. The aim is to help achieve a high-quality standard of [ 18 F]FDG brain imaging and to further increase the diagnostic impact of this technique in neurological, neurosurgical, and psychiatric practice. The present document replaces a former version of the guidelines that have been published in 2009. These new guidelines include an update in the light of advances in PET technology such as the introduction of digital PET and hybrid PET/MR systems, advances in individual PET semiquantitative analysis, and current broadening clinical indications (e.g., for encephalitis and brain lymphoma). Further insight has also become available about hyperglycemia effects in patients who undergo brain [ 18 F]FDG-PET. Accordingly, the patient preparation procedure has been updated. Finally, most typical brain patterns of metabolic changes are summarized for neurodegenerative diseases. The present guidelines are specifically intended to present information related to the European practice. The information provided should be taken in the context of local conditions and regulations.