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Staphylococcus aureus can degrade exogenous fatty acids through β-oxidation
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Journal Article
Staphylococcus aureus can degrade exogenous fatty acids through β-oxidation
2026
Overview
There have been limited studies on the fatty acid degradation (Fad) pathway of Staphylococcus aureus . The fadXDEBA operon has been shown to contain all the genes necessary for β-oxidation, and the FadD and FadBA proteins have been shown to perform their canonical functions. This study demonstrates that the full S. aureus Fad pathway is functional and capable of degrading exogenous fatty acids. These data bring to light a second exogenous fatty acid utilization pathway, expanding our knowledge on how this pathogen metabolizes environmental fatty acids.
Publisher
American Society for Microbiology,American Society for Microbiology (ASM)
Subject
/ Bacterial Proteins - genetics
/ Bacterial Proteins - metabolism
/ Fatty Acid Degradation (Beta-Oxidation)
/ Gene Expression Regulation, Bacterial
/ Metabolic Networks and Pathways - genetics
/ Microbial Pathogenesis and Immunology
/ Microbial Physiology and Genetics
/ MRSA
/ Operon
/ Regulation of Lipid Metabolism
/ Staphylococcus aureus - genetics
/ Staphylococcus aureus - metabolism
