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Bayesian Adaptive Methods for Clinical Trials
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eBook
Bayesian Adaptive Methods for Clinical Trials
2010,2011
Overview
Written by leading pioneers of Bayesian clinical trial designs, this book explores the growing role of Bayesian thinking in clinical trial analysis. Covering Phase I, II, and III clinical trials, it establishes the basic principles before extending them to specific phases and endpoints. The authors also discuss special topics that span different phases of the process, including the use of historical data, equivalence studies, multiplicity and multiple comparisons, and subgroup analysis. They provide many detailed examples drawing on real data sets. Along with other materials, the R and WinBUGS codes used throughout are available on supporting websites.
Publisher
CRC Press,Taylor & Francis Group
Subject
ISBN
1439825483, 9781439825488
