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P51 Spot the difference? Comparison of clinical characteristics of patients with inducible laryngeal obstruction (ILO) and asthma referred to a severe asthma and airways tertiary centre
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P51 Spot the difference? Comparison of clinical characteristics of patients with inducible laryngeal obstruction (ILO) and asthma referred to a severe asthma and airways tertiary centre
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P51 Spot the difference? Comparison of clinical characteristics of patients with inducible laryngeal obstruction (ILO) and asthma referred to a severe asthma and airways tertiary centre
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Journal Article
P51 Spot the difference? Comparison of clinical characteristics of patients with inducible laryngeal obstruction (ILO) and asthma referred to a severe asthma and airways tertiary centre
2021
Overview
Introduction and ObjectivesPatients referred our tertiary airways service are assessed for potential causation of complex breathlessness, including differential diagnosis of asthma and inducible laryngeal obstruction (ILO).Newman et al (1995) found associations between particular patient variables when comparing patients with asthma and ILO. Further investigation of these and other variables may aid in differential diagnosis and understanding triggers and characterisation of ILO compared to asthma.MethodsRecords for 70 patients with sole diagnoses of either asthma (n=34) or ILO (n=36) were reviewed to investigate patterns of association between a large range of variables relating to these conditions, including demographics, co-morbidities, hospital utilisation and medical treatment. Non-parametric statistics were used to compare diagnosis against categorical, interval and ratio data relating to these variables.ResultsA number of significant associations were found between diagnosis and patient characteristics, summarised in table 1.Results showed that certain demographic variables, co-morbidities and medical treatments differentiated these two groups.Abstract P51 Table 1Patient characistics according to diagnosisConclusionsBy continuing to characterise common clinical characteristics of ILO in comparison to asthma, it is hoped that differentiation from asthma and index of suspicion for ILO will be highlighted to help further understand this clinical condition that co-exists and can mimic asthma.It is of particular interest in the ILO only group that documented symptoms of anxiety were lower than in the group with only asthma, which may help to dispel a common held belief that people with ILO have high anxiety burden.
Publisher
BMJ Publishing Group Ltd and British Thoracic Society,BMJ Publishing Group LTD
