Journal Article

51 Outcomes with single-coil versus dual-coil implantable cardioverter-defibrillators: a meta-analysis

Scott, Paul, Sunderland, Nicholas, Murgatroyd, Francis, Kaura, Amit, Dhillon, Para

2017

Overview

AimsDual-coil implantable cardioverter defibrillator (ICD) leads have traditionally been used over single-coil leads due to concerns regarding high defibrillation thresholds (DFT) and consequent poor shock efficacy. However, accumulating evidence suggests that this position may be unfounded and that dual-coil leads may also be associated with higher complication rates during lead extraction. This meta-analysis collates data comparing dual- and single-coil ICD leads.Methods and resultsElectronic databases were systematically searched for randomised controlled trials (RCT) and non-randomised studies comparing single-coil and dual-coil leads. The mean differences in DFT and summary estimates of the odds-ratio (OR) for first-shock efficacy and the hazard-ratio (HR) for all-cause mortality were calculated using random effects models. Eighteen studies including a total of 1 38 124 patients were identified. Dual-coil leads were associated with a lower DFT compared to single coil leads (mean difference –0.83J; 95% confidence interval [CI] –1.39–−0.27; p=0.004). There was no difference in the first-shock success rate with dual-coil compared to single-coil leads (OR 0.74; 95% CI 0.45–1.21; p=0.22). There was a significantly lower risk of all-cause mortality associated with single-coil leads (HR 0.91; 95% CI 0.86–0.95; p<0.0001).ConclusionThis meta-analysis suggests that single-coil leads have a marginally higher DFT but that this may be clinically insignificant as there appears to be no difference in first-shock efficacy when compared to dual-coil leads. The mortality benefit with single-coil leads most likely represents patient selection bias. Given the increased risk and complexity of extracting dual-coil leads, centres should strongly consider single-coil ICD leads as the lead of choice for routine new left-sided ICD implants.

• Publisher: BMJ Publishing Group LTD