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Sensitivity Analysis for Healthcare Models Fitted to Data by Statistical Methods
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Sensitivity Analysis for Healthcare Models Fitted to Data by Statistical Methods
Sensitivity Analysis for Healthcare Models Fitted to Data by Statistical Methods
Journal Article

Sensitivity Analysis for Healthcare Models Fitted to Data by Statistical Methods

2002
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Overview
After fitting complex models to data using statistical methods, a sensitivity analysis can be carried out. This determines which parts of a model are causing the bulk of the uncertainty in the model predictions (model \"output\"), and is a decision-support tool for the modeller who contemplates refining a model further or collecting additional data. A simple methodology for carrying out a sensitivity analysis is described. It is envisaged that such a relatively quick insight-generating step would precede the use of a more formal decision-theoretic approach that would address specific questions. Its use is illustrated using a model for breast cancer screening previously published in this journal. A simpler 3-parameter screening model is used in a simulation study of the error of the method as a function of sample size.