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Placental transmogrification of the lung presenting as progressive symptomatic bullous emphysema
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Placental transmogrification of the lung presenting as progressive symptomatic bullous emphysema
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Journal Article
Placental transmogrification of the lung presenting as progressive symptomatic bullous emphysema
2017
Overview
PLT is regarded as a rare variant of bullous emphysema that mainly affects young to middle-aged subjects. 1 Clinical symptoms include dyspnoea, coughing, pneumonia, chest pain and pneumothorax. 2 Due to the slowly progressive nature of the disease, PLT may lead to functional impairment and adverse events, including infections or, as in the present case, compression of the contralateral lung due to mediastinal displacement. The clear cell proliferation mimics perivascular epithelioid cell-related disorders, including lymphangioleiomyomatosis or clear cell 'sugar' tumours, whereas from the clinical-radiological presentation, the characteristic histology and CD10 expression in the absence of HMB-45 immunoreactivity favour PLT.
Publisher
BMJ Publishing Group LTD
