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Intravenous lipid emulsion for a life-threatening prothipendyl intoxication
by
Deville, Marine
, Demaret, Pierre
, Meunier, Anne
, Goffin, Pierre
in
Adult intensive care
/ Anesthesia & intensive care
/ Anesthésie & soins intensifs
/ Antipsychotic Agents
/ Antipsychotics
/ Cardiac arrhythmia
/ Cardiovascular system
/ Case reports
/ Case Reports: Adverse drug reactions and complications
/ Drug interactions
/ Drug overdose
/ Drug testing
/ Drugs and medicines
/ Enzymes
/ Fat Emulsions, Intravenous
/ Fat Emulsions, Intravenous - therapeutic use
/ Human health sciences
/ Humans
/ Intensive care
/ Intoxication
/ Lipids
/ Medicine (all)
/ Metabolism
/ Metabolites
/ Patients
/ Pharmacokinetics
/ Plasma
/ Poisoning
/ prothipendyl
/ Sciences de la santé humaine
/ Thiazines
/ Toxicology
2024
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Intravenous lipid emulsion for a life-threatening prothipendyl intoxication
by
Deville, Marine
, Demaret, Pierre
, Meunier, Anne
, Goffin, Pierre
in
Adult intensive care
/ Anesthesia & intensive care
/ Anesthésie & soins intensifs
/ Antipsychotic Agents
/ Antipsychotics
/ Cardiac arrhythmia
/ Cardiovascular system
/ Case reports
/ Case Reports: Adverse drug reactions and complications
/ Drug interactions
/ Drug overdose
/ Drug testing
/ Drugs and medicines
/ Enzymes
/ Fat Emulsions, Intravenous
/ Fat Emulsions, Intravenous - therapeutic use
/ Human health sciences
/ Humans
/ Intensive care
/ Intoxication
/ Lipids
/ Medicine (all)
/ Metabolism
/ Metabolites
/ Patients
/ Pharmacokinetics
/ Plasma
/ Poisoning
/ prothipendyl
/ Sciences de la santé humaine
/ Thiazines
/ Toxicology
2024
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Intravenous lipid emulsion for a life-threatening prothipendyl intoxication
by
Deville, Marine
, Demaret, Pierre
, Meunier, Anne
, Goffin, Pierre
in
Adult intensive care
/ Anesthesia & intensive care
/ Anesthésie & soins intensifs
/ Antipsychotic Agents
/ Antipsychotics
/ Cardiac arrhythmia
/ Cardiovascular system
/ Case reports
/ Case Reports: Adverse drug reactions and complications
/ Drug interactions
/ Drug overdose
/ Drug testing
/ Drugs and medicines
/ Enzymes
/ Fat Emulsions, Intravenous
/ Fat Emulsions, Intravenous - therapeutic use
/ Human health sciences
/ Humans
/ Intensive care
/ Intoxication
/ Lipids
/ Medicine (all)
/ Metabolism
/ Metabolites
/ Patients
/ Pharmacokinetics
/ Plasma
/ Poisoning
/ prothipendyl
/ Sciences de la santé humaine
/ Thiazines
/ Toxicology
2024
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Intravenous lipid emulsion for a life-threatening prothipendyl intoxication
Journal Article
Intravenous lipid emulsion for a life-threatening prothipendyl intoxication
2024
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Overview
Prothipendyl, a lipophilic neuroleptic drug, requires a careful dosage regimen due to its potential side effects, including life-threatening arrhythmias.This report outlines a case of severe prothipendyl intoxication, its management and the successful utilisation of Intralipid, an intravenous lipid emulsion, in treating ventricular arrhythmia postmassive prothipendyl ingestion. Additionally, the mechanism of action of Intralipid and the rebound concentration of the lipophilic drug in such scenarios are discussed.
Publisher
BMJ Publishing Group Ltd,BMJ Publishing Group LTD,BMJ Publishing Group
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