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Rare presentation of cutaneous cryptococcosis in advanced HIV
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Rare presentation of cutaneous cryptococcosis in advanced HIV
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Journal Article
Rare presentation of cutaneous cryptococcosis in advanced HIV
2018
Overview
Cryptococcus neoformans is an encapsulated yeast which causes opportunistic infection in the context of immunosuppression, including advanced HIV infection. Cryptococcal infection is systemic and can result in a fatal meningoencephalitis. Cutaneous lesions occur in 15% of those with systemic cryptococcosis and may be the first indicator of infection. Identification of these lesions may therefore expedite diagnosis and access to treatment. Cutaneous lesions typically present as papulonodular molluscum-like lesions; however, may vary significantly in appearance. We describe a rare case of extraneuronal cryptococcal infection manifesting as large subcutaneous tumours in a patient with advanced HIV-related immune deficiency.
Publisher
BMJ Publishing Group LTD,BMJ Publishing Group
Subject
Acquired immune deficiency syndrome
/ AIDS
/ AIDS-Related Opportunistic Infections - diagnosis
/ AIDS-Related Opportunistic Infections - drug therapy
/ Antifungal Agents - administration & dosage
/ Antifungal Agents - therapeutic use
/ Antigens
/ Cryptococcosis - drug therapy
/ Cryptococcus neoformans - isolation & purification
/ Fluconazole - administration & dosage
/ Fluconazole - therapeutic use
/ HIV
/ Human immunodeficiency virus
/ Humans
/ Male
/ Patients
