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Improved, High Yield Synthesis of 3H-Quinazolin-4-ones, the Key Intermediates of Recently Developed Drugs
by
Istvan Varga
, Janos Pato
, Frigyes Waczek
, Gyorgy Ker
, Laszlo Orfi
, Balint Hegymegi-Barakonyi
, Richard Houghten
in
antiproliferative agents
/ Biological and medical sciences
/ Drugs, Investigational - chemical synthesis
/ Drugs, Investigational - metabolism
/ formamidine-acetate
/ imidoyl-chlorides
/ Lung cancer
/ Medical sciences
/ Miscellaneous
/ Pharmacology. Drug treatments
/ phosphodiesterase V inhibitors
/ protein kinase inhibitors
/ purine analogs
/ Pyrimidines
/ quinazolin-4-ones
/ Quinazolines - chemical synthesis
/ Quinazolines - metabolism
/ Tritium - chemistry
/ Tritium - metabolism
2004
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Improved, High Yield Synthesis of 3H-Quinazolin-4-ones, the Key Intermediates of Recently Developed Drugs
by
Istvan Varga
, Janos Pato
, Frigyes Waczek
, Gyorgy Ker
, Laszlo Orfi
, Balint Hegymegi-Barakonyi
, Richard Houghten
in
antiproliferative agents
/ Biological and medical sciences
/ Drugs, Investigational - chemical synthesis
/ Drugs, Investigational - metabolism
/ formamidine-acetate
/ imidoyl-chlorides
/ Lung cancer
/ Medical sciences
/ Miscellaneous
/ Pharmacology. Drug treatments
/ phosphodiesterase V inhibitors
/ protein kinase inhibitors
/ purine analogs
/ Pyrimidines
/ quinazolin-4-ones
/ Quinazolines - chemical synthesis
/ Quinazolines - metabolism
/ Tritium - chemistry
/ Tritium - metabolism
2004
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Improved, High Yield Synthesis of 3H-Quinazolin-4-ones, the Key Intermediates of Recently Developed Drugs
by
Istvan Varga
, Janos Pato
, Frigyes Waczek
, Gyorgy Ker
, Laszlo Orfi
, Balint Hegymegi-Barakonyi
, Richard Houghten
in
antiproliferative agents
/ Biological and medical sciences
/ Drugs, Investigational - chemical synthesis
/ Drugs, Investigational - metabolism
/ formamidine-acetate
/ imidoyl-chlorides
/ Lung cancer
/ Medical sciences
/ Miscellaneous
/ Pharmacology. Drug treatments
/ phosphodiesterase V inhibitors
/ protein kinase inhibitors
/ purine analogs
/ Pyrimidines
/ quinazolin-4-ones
/ Quinazolines - chemical synthesis
/ Quinazolines - metabolism
/ Tritium - chemistry
/ Tritium - metabolism
2004
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Improved, High Yield Synthesis of 3H-Quinazolin-4-ones, the Key Intermediates of Recently Developed Drugs
Journal Article
Improved, High Yield Synthesis of 3H-Quinazolin-4-ones, the Key Intermediates of Recently Developed Drugs
2004
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Overview
Purine bases and their bioisosteric analogs are widely used as building blocks in combinatorial chemistry. Recently a great number of fused pyrimidine derivatives became known as potential drug molecules against various types of proliferative diseases, caused by over-expression of protein kinases [1]. One of the most important compound
Publisher
Bentham Science Publishers Ltd,Bentham Science Publishers,Bentham Science
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