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Coronary Stents: The Impact of Technological Advances on Clinical Outcomes
by
Pagnotta, Paolo A.
, Mennuni, Marco G.
, Stefanini, Giulio G.
in
Antiproliferatives
/ Arteries
/ Biochemistry
/ Biodegradation
/ Biological and Medical Physics
/ Biomedical and Life Sciences
/ Biomedical Engineering and Bioengineering
/ Biomedicine
/ Biophysics
/ Classical Mechanics
/ Clinical outcomes
/ Coronary Vessels - physiopathology
/ Coronary Vessels - surgery
/ Durability
/ Graft Occlusion, Vascular - physiopathology
/ Graft Occlusion, Vascular - prevention & control
/ Humans
/ Medical equipment
/ Medical services
/ Medical Stents: State of the Art and Future Directions
/ Percutaneous Coronary Intervention - methods
/ Percutaneous Coronary Intervention - trends
/ Polymers
/ Risk
/ Stents
/ Stents - trends
/ Surgical implants
2016
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Coronary Stents: The Impact of Technological Advances on Clinical Outcomes
by
Pagnotta, Paolo A.
, Mennuni, Marco G.
, Stefanini, Giulio G.
in
Antiproliferatives
/ Arteries
/ Biochemistry
/ Biodegradation
/ Biological and Medical Physics
/ Biomedical and Life Sciences
/ Biomedical Engineering and Bioengineering
/ Biomedicine
/ Biophysics
/ Classical Mechanics
/ Clinical outcomes
/ Coronary Vessels - physiopathology
/ Coronary Vessels - surgery
/ Durability
/ Graft Occlusion, Vascular - physiopathology
/ Graft Occlusion, Vascular - prevention & control
/ Humans
/ Medical equipment
/ Medical services
/ Medical Stents: State of the Art and Future Directions
/ Percutaneous Coronary Intervention - methods
/ Percutaneous Coronary Intervention - trends
/ Polymers
/ Risk
/ Stents
/ Stents - trends
/ Surgical implants
2016
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Coronary Stents: The Impact of Technological Advances on Clinical Outcomes
by
Pagnotta, Paolo A.
, Mennuni, Marco G.
, Stefanini, Giulio G.
in
Antiproliferatives
/ Arteries
/ Biochemistry
/ Biodegradation
/ Biological and Medical Physics
/ Biomedical and Life Sciences
/ Biomedical Engineering and Bioengineering
/ Biomedicine
/ Biophysics
/ Classical Mechanics
/ Clinical outcomes
/ Coronary Vessels - physiopathology
/ Coronary Vessels - surgery
/ Durability
/ Graft Occlusion, Vascular - physiopathology
/ Graft Occlusion, Vascular - prevention & control
/ Humans
/ Medical equipment
/ Medical services
/ Medical Stents: State of the Art and Future Directions
/ Percutaneous Coronary Intervention - methods
/ Percutaneous Coronary Intervention - trends
/ Polymers
/ Risk
/ Stents
/ Stents - trends
/ Surgical implants
2016
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Coronary Stents: The Impact of Technological Advances on Clinical Outcomes
Journal Article
Coronary Stents: The Impact of Technological Advances on Clinical Outcomes
2016
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Overview
Percutaneous coronary interventions (PCI) were proposed in the late 1970s as an alternative to surgical coronary artery bypass grafting for the treatment of coronary artery disease. Important technological progress has been made since. Balloon angioplasty was replaced by bare metal stents, which allowed to permanently scaffold the coronary vessel avoiding acute recoil and abrupt occlusion. Thereafter, the introduction of early generation drug-eluting stents (DES) has significantly improved clinical outcomes, primarily by markedly reducing the risk of restenosis. New generation DES with thinner stent struts, novel durable or biodegradable polymer coatings, and new limus antiproliferative agents, have further improved upon the safety and efficacy profile of early generation DES. The present article aims to review the impact of technological advances on clinical outcomes in the field of PCI with coronary stents, and to provide a brief overview on clinical margins of improvement and unmet needs of available DES.
Publisher
Springer US,Springer Nature B.V
Subject
/ Arteries
/ Biological and Medical Physics
/ Biomedical and Life Sciences
/ Biomedical Engineering and Bioengineering
/ Coronary Vessels - physiopathology
/ Graft Occlusion, Vascular - physiopathology
/ Graft Occlusion, Vascular - prevention & control
/ Humans
/ Medical Stents: State of the Art and Future Directions
/ Percutaneous Coronary Intervention - methods
/ Percutaneous Coronary Intervention - trends
/ Polymers
/ Risk
/ Stents
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