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Dysfunctional missense variant of OAT10/SLC22A13 decreases gout risk and serum uric acid levels

Dysfunctional missense variant of OAT10/SLC22A13 decreases gout risk and serum uric acid levels

by Kawaguchi, Makoto , Yamamoto, Ken , Toyoda, Yu , Takada, Tappei , Ueno, Miki , Ito, Toshimitsu , Suzuki, Hiroshi , Nakayama, Akiyoshi , Ooyama, Keiko , Morimoto, Keito , Osada, Naoki , Shinomiya, Nariyoshi , Naito, Mariko , Kawai, Yosuke , Tamura, Takashi , Matsuo, Hirotaka , Ooyama, Hiroshi , Shimizu, Seiko , Kawamura, Yusuke , Nakashima, Hiroshi , Shimizu, Toru , Ichida, Kimiyoshi , Inoue, Ituro , Higashino, Toshihide , Hosomichi, Kazuyoshi , Nakaoka, Hirofumi , Takao, Mikiya , Nakamura, Takahiro

in Adult / Asian People - genetics / Brush border membranes / Case-Control Studies / Clear cell-type renal cell carcinoma / epidemiology / Epithelium / gene polymorphism / Genetic Predisposition to Disease / Gout / Gout - blood / Gout - genetics / Humans / Hyperuricemia - blood / Hyperuricemia - genetics / Japan / Letter / Localization / Male / Middle Aged / Mutation, Missense / Organic Anion Transporters - genetics / Physiology / Protective Factors / Proteins / Rheumatism / Uric acid / Uric Acid - blood / Urine

2020

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Dysfunctional missense variant of OAT10/SLC22A13 decreases gout risk and serum uric acid levels

by Kawaguchi, Makoto , Yamamoto, Ken , Toyoda, Yu , Takada, Tappei , Ueno, Miki , Ito, Toshimitsu , Suzuki, Hiroshi , Nakayama, Akiyoshi , Ooyama, Keiko , Morimoto, Keito , Osada, Naoki , Shinomiya, Nariyoshi , Naito, Mariko , Kawai, Yosuke , Tamura, Takashi , Matsuo, Hirotaka , Ooyama, Hiroshi , Shimizu, Seiko , Kawamura, Yusuke , Nakashima, Hiroshi , Shimizu, Toru , Ichida, Kimiyoshi , Inoue, Ituro , Higashino, Toshihide , Hosomichi, Kazuyoshi , Nakaoka, Hirofumi , Takao, Mikiya , Nakamura, Takahiro

in Adult / Asian People - genetics / Brush border membranes / Case-Control Studies / Clear cell-type renal cell carcinoma / epidemiology / Epithelium / gene polymorphism / Genetic Predisposition to Disease / Gout / Gout - blood / Gout - genetics / Humans / Hyperuricemia - blood / Hyperuricemia - genetics / Japan / Letter / Localization / Male / Middle Aged / Mutation, Missense / Organic Anion Transporters - genetics / Physiology / Protective Factors / Proteins / Rheumatism / Uric acid / Uric Acid - blood / Urine

2020

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Dysfunctional missense variant of OAT10/SLC22A13 decreases gout risk and serum uric acid levels

Dysfunctional missense variant of OAT10/SLC22A13 decreases gout risk and serum uric acid levels

by Kawaguchi, Makoto , Yamamoto, Ken , Toyoda, Yu , Takada, Tappei , Ueno, Miki , Ito, Toshimitsu , Suzuki, Hiroshi , Nakayama, Akiyoshi , Ooyama, Keiko , Morimoto, Keito , Osada, Naoki , Shinomiya, Nariyoshi , Naito, Mariko , Kawai, Yosuke , Tamura, Takashi , Matsuo, Hirotaka , Ooyama, Hiroshi , Shimizu, Seiko , Kawamura, Yusuke , Nakashima, Hiroshi , Shimizu, Toru , Ichida, Kimiyoshi , Inoue, Ituro , Higashino, Toshihide , Hosomichi, Kazuyoshi , Nakaoka, Hirofumi , Takao, Mikiya , Nakamura, Takahiro

in Adult / Asian People - genetics / Brush border membranes / Case-Control Studies / Clear cell-type renal cell carcinoma / epidemiology / Epithelium / gene polymorphism / Genetic Predisposition to Disease / Gout / Gout - blood / Gout - genetics / Humans / Hyperuricemia - blood / Hyperuricemia - genetics / Japan / Letter / Localization / Male / Middle Aged / Mutation, Missense / Organic Anion Transporters - genetics / Physiology / Protective Factors / Proteins / Rheumatism / Uric acid / Uric Acid - blood / Urine

2020

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Dysfunctional missense variant of OAT10/SLC22A13 decreases gout risk and serum uric acid levels

Journal Article

Dysfunctional missense variant of OAT10/SLC22A13 decreases gout risk and serum uric acid levels

Kawaguchi, Makoto,

Yamamoto, Ken,

Toyoda, Yu,

Takada, Tappei,

Ueno, Miki,

Ito, Toshimitsu,

Suzuki, Hiroshi,

Nakayama, Akiyoshi,

Ooyama, Keiko,

Morimoto, Keito,

Osada, Naoki,

Shinomiya, Nariyoshi,

Naito, Mariko,

Kawai, Yosuke,

Tamura, Takashi,

Matsuo, Hirotaka,

Ooyama, Hiroshi,

Shimizu, Seiko,

Kawamura, Yusuke,

Nakashima, Hiroshi,

Shimizu, Toru,

Ichida, Kimiyoshi,

Inoue, Ituro,

Higashino, Toshihide,

Hosomichi, Kazuyoshi,

Nakaoka, Hirofumi,

Takao, Mikiya,

Nakamura, Takahiro

2020

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Publisher

BMJ Publishing Group Ltd and European League Against Rheumatism,Elsevier Limited,BMJ Publishing Group

Subject

/ Asian People - genetics

/ Brush border membranes

/ Case-Control Studies

/ Clear cell-type renal cell carcinoma

/ gene polymorphism

/ Genetic Predisposition to Disease

/ Gout - genetics

/ Hyperuricemia - blood

/ Hyperuricemia - genetics

/ Mutation, Missense

/ Organic Anion Transporters - genetics

/ Protective Factors

/ Uric Acid - blood

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