Asset Details
Do you wish to reserve the book?
Low Molecular Weight Modifications of Anthracycline Antibiotics. Part II. Reactions by Other Positions (A Review)
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Low Molecular Weight Modifications of Anthracycline Antibiotics. Part II. Reactions by Other Positions (A Review)
Do you wish to request the book?
Low Molecular Weight Modifications of Anthracycline Antibiotics. Part II. Reactions by Other Positions (A Review)
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Low Molecular Weight Modifications of Anthracycline Antibiotics. Part II. Reactions by Other Positions (A Review)
2024
Overview
Abstract―This review continues the discussion of known chemical transformations of anthracyclines, with a primary focus on daunorubicin and doxorubicin. In the first part, various modifications involving the amino group in the amino sugar moiety were explored. The second part shifts attention to modifications occurring at other sites within the anthracycline molecule. These include alterations at the C-13 keto group of the aglycone, such as deoxygenation and imine formation, as well as reactions involving the hydroxy groups at the C-9 and C-14 positions. Additionally, modifications to the A, B, C, and D rings of the anthraquinone nucleus are discussed in detail. Separate consideration is given to anthracyclines with non-classical structures, such as nogalomycin. For each modified anthracycline, data are provided regarding changes in biological activity, particularly with respect to antitumor efficacy and the cardiotoxicity commonly associated with anthracyclines.
Publisher
Springer Nature B.V
We currently cannot retrieve any items related to this title. Kindly check back at a later time.