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肺鳞癌驱动基因研究进展
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肺鳞癌驱动基因研究进展
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Journal Article
肺鳞癌驱动基因研究进展
2014
Overview
肺癌在癌症相关死亡中是居于首位的恶性肿瘤。鳞癌是仅次于腺癌的非小细胞肺癌（non-small cell lung cancer, NSCLC）最常见的组织学类型。一些负责恶性肿瘤的发生和维持相关分子改变被称为驱动基因。近来研究证实肺鳞癌也具有与致癌作用及靶向药物疗效有关的独特分子特征。目前发现约40%肺鳞癌已经找到驱动基因，其中纤维母细胞生长因子受体1（ifbroblast growth factor receptor 1, FGFR1）起重要作用。本文将对肺鳞癌驱动基因进行综述。
Publisher
310022杭州，浙江省肿瘤医院，浙江省胸部肿瘤诊治技术研究重点实验室,中国肺癌杂志编辑部
Subject
